Motif ID: Hey2

Z-value: 0.678


Transcription factors associated with Hey2:

Gene SymbolEntrez IDGene Name
Hey2 ENSMUSG00000019789.8 Hey2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hey2mm10_v2_chr10_-_30842765_30842801-0.253.9e-02Click!


Activity profile for motif Hey2.

activity profile for motif Hey2


Sorted Z-values histogram for motif Hey2

Sorted Z-values for motif Hey2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hey2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 186 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_14523178 8.441 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr11_-_120348513 6.077 ENSMUST00000071555.6
 Actg1
actin, gamma, cytoplasmic 1
chr18_-_61911783 5.996 ENSMUST00000049378.8
ENSMUST00000166783.1
 Ablim3

actin binding LIM protein family, member 3

chr4_+_33924632 5.884 ENSMUST00000057188.6
 Cnr1
cannabinoid receptor 1 (brain)
chr6_-_88875035 5.719 ENSMUST00000145944.1
 Podxl2
podocalyxin-like 2
chr4_+_104367549 5.596 ENSMUST00000106830.2
 Dab1
disabled 1
chr6_+_54816906 5.558 ENSMUST00000079869.6
 Znrf2
zinc and ring finger 2
chr11_+_120721452 5.348 ENSMUST00000018156.5
 Rac3
RAS-related C3 botulinum substrate 3
chr16_-_18621366 5.039 ENSMUST00000051160.2
 Gp1bb
glycoprotein Ib, beta polypeptide
chr2_-_168741898 4.736 ENSMUST00000109176.1
ENSMUST00000178504.1
 Atp9a

ATPase, class II, type 9A

chr11_+_120721543 4.477 ENSMUST00000142229.1
 Rac3
RAS-related C3 botulinum substrate 3
chr2_-_85196697 4.381 ENSMUST00000099930.2
ENSMUST00000111601.1
 Lrrc55

leucine rich repeat containing 55

chr19_+_6418731 4.214 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
 Nrxn2


neurexin II


chr8_-_70700070 4.060 ENSMUST00000116172.1
 Gm11175
predicted gene 11175
chr9_+_21165714 3.924 ENSMUST00000039413.8
 Pde4a
phosphodiesterase 4A, cAMP specific
chr2_-_114013619 3.820 ENSMUST00000090275.4
 Gjd2
gap junction protein, delta 2
chr4_+_85205120 3.810 ENSMUST00000107188.3
 Sh3gl2
SH3-domain GRB2-like 2
chr4_-_11966368 3.739 ENSMUST00000056050.4
ENSMUST00000108299.1
ENSMUST00000108297.2
 Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr7_+_44384604 3.624 ENSMUST00000130707.1
ENSMUST00000130844.1
 Syt3

synaptotagmin III

chr11_-_120348475 3.318 ENSMUST00000062147.7
ENSMUST00000128055.1
 Actg1

actin, gamma, cytoplasmic 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 10.8 GO:0045214 sarcomere organization(GO:0045214)
1.1 9.8 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.2 9.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.6 8.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 8.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
1.5 5.9 GO:0031622 positive regulation of fever generation(GO:0031622)
1.9 5.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 5.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 4.9 GO:0007596 blood coagulation(GO:0007596)
0.1 3.9 GO:0007608 sensory perception of smell(GO:0007608)
0.1 3.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
1.2 3.7 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.3 3.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 3.6 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.2 3.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 3.3 GO:0007601 visual perception(GO:0007601)
0.8 3.2 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.3 3.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 3.2 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0 3.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 20.7 GO:0031941 filamentous actin(GO:0031941)
0.0 12.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 10.6 GO:0055037 recycling endosome(GO:0055037)
0.1 6.1 GO:0042734 presynaptic membrane(GO:0042734)
0.1 5.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 5.6 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 5.6 GO:0005903 brush border(GO:0005903)
0.0 4.0 GO:0070382 exocytic vesicle(GO:0070382)
0.3 3.8 GO:0005922 connexon complex(GO:0005922)
0.7 3.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5 3.2 GO:0005638 lamin filament(GO:0005638)
0.2 3.1 GO:0031209 SCAR complex(GO:0031209)
0.1 2.8 GO:0002102 podosome(GO:0002102)
0.8 2.4 GO:0044194 cytolytic granule(GO:0044194)
0.1 2.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.4 GO:0005902 microvillus(GO:0005902)
0.0 2.4 GO:0030016 myofibril(GO:0030016)
0.0 2.3 GO:0030118 clathrin coat(GO:0030118)
0.1 2.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.1 GO:0060077 inhibitory synapse(GO:0060077)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.7 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.2 12.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 9.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 7.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 5.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 4.8 GO:0008144 drug binding(GO:0008144)
0.1 4.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 3.9 GO:0030552 cAMP binding(GO:0030552)
0.9 3.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.7 3.7 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 3.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.6 3.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 3.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 3.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 3.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.0 2.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 2.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 2.7 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.2 2.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)