Motif ID: Hivep1

Z-value: 0.746


Transcription factors associated with Hivep1:

Gene SymbolEntrez IDGene Name
Hivep1 ENSMUSG00000021366.7 Hivep1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hivep1mm10_v2_chr13_+_42052015_420520720.515.2e-06Click!


Activity profile for motif Hivep1.

activity profile for motif Hivep1


Sorted Z-values histogram for motif Hivep1

Sorted Z-values for motif Hivep1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hivep1

PNG image of the network

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Top targets:


Showing 1 to 20 of 148 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_88000350 8.856 ENSMUST00000090971.5
 Bcan
brevican
chr10_-_27616895 5.846 ENSMUST00000092639.5
 Lama2
laminin, alpha 2
chr4_-_82505749 5.043 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr2_-_113758638 3.924 ENSMUST00000099575.3
 Grem1
gremlin 1
chr14_+_80000292 3.856 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr15_-_79164477 3.367 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr18_+_37496997 2.741 ENSMUST00000059571.5
 Pcdhb19
protocadherin beta 19
chr16_+_38089001 2.682 ENSMUST00000023507.6
 Gsk3b
glycogen synthase kinase 3 beta
chr5_-_134747241 2.450 ENSMUST00000015138.9
 Eln
elastin
chr1_-_156204998 2.448 ENSMUST00000015628.3
 Fam163a
family with sequence similarity 163, member A
chr7_+_99535652 2.448 ENSMUST00000032995.8
ENSMUST00000162404.1
 Arrb1

arrestin, beta 1

chr3_-_107760221 2.415 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
 Csf1


colony stimulating factor 1 (macrophage)


chr7_+_99535439 2.408 ENSMUST00000098266.2
ENSMUST00000179755.1
 Arrb1

arrestin, beta 1

chr2_-_5063996 2.272 ENSMUST00000114996.1
 Optn
optineurin
chr7_+_27653906 2.250 ENSMUST00000008088.7
 Ttc9b
tetratricopeptide repeat domain 9B
chr2_-_104257400 2.231 ENSMUST00000141159.1
 D430041D05Rik
RIKEN cDNA D430041D05 gene
chr6_-_97487801 2.169 ENSMUST00000113353.1
ENSMUST00000032146.7
 Frmd4b

FERM domain containing 4B

chr1_+_64532790 2.031 ENSMUST00000049932.5
ENSMUST00000087366.4
ENSMUST00000171164.1
 Creb1


cAMP responsive element binding protein 1


chr18_+_37477768 2.020 ENSMUST00000051442.5
 Pcdhb16
protocadherin beta 16
chr3_+_117575268 2.002 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.9 GO:0021766 hippocampus development(GO:0021766)
1.2 5.8 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.3 5.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 4.9 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
1.1 4.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 4.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
1.3 3.9 GO:1901228 regulation of osteoclast proliferation(GO:0090289) negative regulation of bone mineralization involved in bone maturation(GO:1900158) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.3 3.4 GO:0048484 enteric nervous system development(GO:0048484)
0.7 2.8 GO:0009597 detection of virus(GO:0009597)
0.2 2.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 2.8 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.9 2.7 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.3 2.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 2.5 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
1.2 2.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 2.2 GO:0098792 xenophagy(GO:0098792)
0.7 2.0 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.1 2.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.6 1.9 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.3 1.9 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.9 GO:0031225 anchored component of membrane(GO:0031225)
0.2 5.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 4.9 GO:0031143 pseudopodium(GO:0031143)
0.1 4.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 3.9 GO:0042581 specific granule(GO:0042581)
0.4 3.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 2.8 GO:0005923 bicellular tight junction(GO:0005923)
0.2 2.7 GO:1990909 Wnt signalosome(GO:1990909)
0.1 2.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.7 GO:0005802 trans-Golgi network(GO:0005802)
0.8 2.5 GO:0071953 elastic fiber(GO:0071953)
0.8 2.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 2.1 GO:0005605 basal lamina(GO:0005605)
0.0 2.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.0 GO:0060170 ciliary membrane(GO:0060170)
0.0 2.0 GO:0009986 cell surface(GO:0009986)
0.0 1.7 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.5 1.5 GO:0000802 transverse filament(GO:0000802)
0.2 1.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 8.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 5.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.6 4.9 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.5 4.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.4 3.9 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 3.9 GO:0045296 cadherin binding(GO:0045296)
0.1 3.4 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 2.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 2.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 2.7 GO:0005125 cytokine activity(GO:0005125)
0.5 2.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.9 GO:0042393 histone binding(GO:0042393)
0.1 1.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 1.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)