Motif ID: Hivep1
Z-value: 0.746
Transcription factors associated with Hivep1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hivep1 | ENSMUSG00000021366.7 | Hivep1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hivep1 | mm10_v2_chr13_+_42052015_42052072 | 0.51 | 5.2e-06 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 3.9 | GO:1901228 | regulation of osteoclast proliferation(GO:0090289) negative regulation of bone mineralization involved in bone maturation(GO:1900158) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
| 1.3 | 5.0 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 1.2 | 2.4 | GO:0002158 | osteoclast proliferation(GO:0002158) |
| 1.2 | 5.8 | GO:0032224 | positive regulation of synaptic transmission, cholinergic(GO:0032224) |
| 1.1 | 4.2 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.9 | 2.7 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.7 | 2.8 | GO:0009597 | detection of virus(GO:0009597) |
| 0.7 | 4.9 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.7 | 2.0 | GO:0032916 | positive regulation of transforming growth factor beta3 production(GO:0032916) |
| 0.6 | 1.9 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
| 0.4 | 1.3 | GO:1904884 | telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 0.4 | 0.8 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.4 | 1.5 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
| 0.3 | 0.9 | GO:0048352 | neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) |
| 0.3 | 1.9 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.3 | 0.9 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
| 0.3 | 3.4 | GO:0048484 | enteric nervous system development(GO:0048484) |
| 0.3 | 1.6 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.3 | 1.9 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.3 | 1.0 | GO:0061428 | positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.3 | 2.6 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.3 | 0.5 | GO:0046878 | positive regulation of saliva secretion(GO:0046878) |
| 0.2 | 0.7 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
| 0.2 | 2.8 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.2 | 0.9 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.1 | 0.4 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 0.1 | 1.5 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.1 | 2.5 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.1 | 0.8 | GO:1902373 | negative regulation of mRNA catabolic process(GO:1902373) |
| 0.1 | 1.1 | GO:0043084 | penile erection(GO:0043084) |
| 0.1 | 0.8 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.1 | 0.6 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
| 0.1 | 8.9 | GO:0021766 | hippocampus development(GO:0021766) |
| 0.1 | 1.5 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
| 0.1 | 1.1 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 2.0 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.9 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.1 | 1.2 | GO:0010748 | negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.1 | 1.2 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 4.1 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
| 0.1 | 0.5 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 0.6 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.6 | GO:1902287 | semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
| 0.0 | 0.2 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 1.3 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 1.0 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
| 0.0 | 0.6 | GO:0030575 | nuclear body organization(GO:0030575) |
| 0.0 | 0.4 | GO:0090331 | negative regulation of platelet aggregation(GO:0090331) |
| 0.0 | 0.5 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.0 | 0.9 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.0 | 0.1 | GO:0043652 | engulfment of apoptotic cell(GO:0043652) |
| 0.0 | 2.8 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
| 0.0 | 0.3 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.0 | 0.1 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 0.0 | 0.1 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 2.2 | GO:0098792 | xenophagy(GO:0098792) |
| 0.0 | 0.4 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.6 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 1.1 | GO:0006497 | protein lipidation(GO:0006497) |
| 0.0 | 0.1 | GO:1901409 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.5 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.8 | 2.4 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.5 | 1.5 | GO:0000802 | transverse filament(GO:0000802) |
| 0.4 | 3.4 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
| 0.3 | 4.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.3 | 3.9 | GO:0042581 | specific granule(GO:0042581) |
| 0.2 | 1.5 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
| 0.2 | 2.7 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.2 | 5.0 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.2 | 1.0 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.2 | 1.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.2 | 0.5 | GO:0032127 | dense core granule membrane(GO:0032127) |
| 0.1 | 1.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 1.5 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 4.2 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 1.3 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 0.6 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.1 | 2.1 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 8.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 1.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 0.6 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 1.3 | GO:0001741 | XY body(GO:0001741) |
| 0.1 | 2.7 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 0.6 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 2.1 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 2.0 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.5 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.8 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.5 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.0 | 0.9 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 2.8 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 2.0 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 0.2 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 1.6 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 1.7 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 0.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 2.7 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.9 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.9 | GO:0005901 | caveola(GO:0005901) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.9 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.5 | 4.2 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 0.5 | 2.5 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.5 | 8.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.4 | 3.9 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.3 | 1.0 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903) |
| 0.2 | 0.7 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
| 0.2 | 1.5 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.2 | 1.3 | GO:0032405 | MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407) |
| 0.2 | 0.7 | GO:0004096 | catalase activity(GO:0004096) |
| 0.2 | 0.9 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.2 | 0.5 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 0.1 | 2.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 1.5 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.1 | 5.0 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 2.0 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.1 | 1.1 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 2.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 1.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 3.9 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 1.8 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 0.6 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.1 | 0.5 | GO:0015168 | glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254) |
| 0.1 | 1.0 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.1 | 3.4 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.1 | 1.6 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.1 | 1.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.6 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 1.1 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 2.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 1.7 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 0.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.3 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 1.3 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 2.7 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.4 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.8 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 1.2 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.6 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.9 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 1.9 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 0.5 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.1 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.0 | 0.8 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.2 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 0.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
