Motif ID: Hmbox1
Z-value: 0.920
Transcription factors associated with Hmbox1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hmbox1 | ENSMUSG00000021972.8 | Hmbox1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hmbox1 | mm10_v2_chr14_-_64949838_64949886 | 0.20 | 9.2e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.3 | 19.7 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
1.6 | 11.5 | GO:0000022 | mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256) |
1.5 | 15.5 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
1.3 | 5.3 | GO:2000668 | dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) |
0.6 | 2.6 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
0.6 | 1.7 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
0.6 | 3.4 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
0.5 | 1.6 | GO:0031627 | telomeric loop formation(GO:0031627) |
0.5 | 4.8 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.4 | 7.4 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
0.4 | 4.8 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.3 | 2.4 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.3 | 3.7 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
0.3 | 5.0 | GO:0051451 | myoblast migration(GO:0051451) |
0.3 | 3.4 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.3 | 3.5 | GO:0048664 | neuron fate determination(GO:0048664) |
0.3 | 2.0 | GO:0007343 | egg activation(GO:0007343) |
0.2 | 3.0 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.2 | 2.3 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.2 | 6.0 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.1 | 0.4 | GO:2000834 | androgen secretion(GO:0035935) testosterone secretion(GO:0035936) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845) |
0.1 | 3.4 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
0.1 | 4.7 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.1 | 2.2 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.1 | 0.9 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
0.1 | 0.7 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 1.7 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
0.1 | 0.3 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
0.1 | 0.3 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
0.1 | 1.1 | GO:0043248 | proteasome assembly(GO:0043248) |
0.1 | 1.9 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-dependent nucleosome organization(GO:0034723) DNA replication-independent nucleosome organization(GO:0034724) |
0.1 | 0.8 | GO:0046500 | S-adenosylmethionine metabolic process(GO:0046500) |
0.1 | 0.2 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.1 | 0.4 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 0.2 | GO:0032298 | positive regulation of DNA-dependent DNA replication initiation(GO:0032298) |
0.0 | 1.8 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 1.1 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
0.0 | 2.6 | GO:0002224 | toll-like receptor signaling pathway(GO:0002224) |
0.0 | 2.9 | GO:0006821 | chloride transport(GO:0006821) |
0.0 | 6.3 | GO:0022409 | positive regulation of cell-cell adhesion(GO:0022409) |
0.0 | 1.6 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.7 | GO:0043277 | apoptotic cell clearance(GO:0043277) |
0.0 | 3.8 | GO:0000910 | cytokinesis(GO:0000910) |
0.0 | 1.0 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.6 | GO:0030262 | cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262) |
0.0 | 0.7 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.9 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.0 | 1.3 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
0.0 | 1.0 | GO:0016574 | histone ubiquitination(GO:0016574) |
0.0 | 0.3 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.3 | GO:0045116 | protein neddylation(GO:0045116) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.9 | 15.5 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
1.1 | 3.4 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
0.7 | 3.4 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.5 | 2.5 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.4 | 2.3 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.3 | 5.3 | GO:0043657 | host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) |
0.2 | 1.6 | GO:0070187 | telosome(GO:0070187) |
0.2 | 10.6 | GO:0005871 | kinesin complex(GO:0005871) |
0.1 | 4.0 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.1 | 1.0 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 1.0 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.1 | 1.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 1.6 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.1 | 3.4 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 0.8 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.1 | 4.4 | GO:0016459 | myosin complex(GO:0016459) |
0.1 | 0.7 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.1 | 7.9 | GO:0030496 | midbody(GO:0030496) |
0.1 | 0.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.1 | 0.4 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.0 | 0.5 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 2.6 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 4.9 | GO:0005874 | microtubule(GO:0005874) |
0.0 | 7.4 | GO:0005681 | spliceosomal complex(GO:0005681) |
0.0 | 0.8 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
0.0 | 0.5 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
0.0 | 1.1 | GO:0090544 | BAF-type complex(GO:0090544) |
0.0 | 0.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.0 | 4.8 | GO:0005769 | early endosome(GO:0005769) |
0.0 | 1.4 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 2.8 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
0.0 | 1.7 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.6 | GO:0031526 | brush border membrane(GO:0031526) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 10.6 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.6 | 1.7 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) |
0.5 | 5.3 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.5 | 3.0 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.4 | 3.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.4 | 2.3 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.3 | 1.9 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.3 | 3.4 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.3 | 1.1 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.2 | 5.0 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.2 | 1.6 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
0.2 | 0.8 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.1 | 1.7 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 3.4 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.1 | 6.3 | GO:0030507 | spectrin binding(GO:0030507) |
0.1 | 0.9 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.1 | 3.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.1 | 0.7 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 4.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
0.1 | 1.2 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.1 | 1.2 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.1 | 17.3 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.1 | 17.4 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.1 | 0.3 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.1 | 1.1 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.1 | 1.2 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.1 | 0.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 6.2 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.0 | 2.2 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 2.9 | GO:0005254 | chloride channel activity(GO:0005254) |
0.0 | 0.4 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.0 | 0.7 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
0.0 | 4.7 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
0.0 | 0.2 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.0 | 4.2 | GO:0047485 | protein N-terminus binding(GO:0047485) |
0.0 | 1.8 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
0.0 | 0.5 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 3.2 | GO:0000287 | magnesium ion binding(GO:0000287) |
0.0 | 0.4 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.0 | 0.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.3 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.0 | 0.3 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.0 | 7.9 | GO:0044212 | transcription regulatory region DNA binding(GO:0044212) |