Motif ID: Hmbox1

Z-value: 0.920


Transcription factors associated with Hmbox1:

Gene SymbolEntrez IDGene Name
Hmbox1 ENSMUSG00000021972.8 Hmbox1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmbox1mm10_v2_chr14_-_64949838_649498860.209.2e-02Click!


Activity profile for motif Hmbox1.

activity profile for motif Hmbox1


Sorted Z-values histogram for motif Hmbox1

Sorted Z-values for motif Hmbox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmbox1

PNG image of the network

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Top targets:


Showing 1 to 20 of 134 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 19.677 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr6_+_5390387 15.487 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chrX_+_100625737 11.517 ENSMUST00000048962.3
 Kif4
kinesin family member 4
chr3_-_100969644 7.409 ENSMUST00000076941.5
 Ttf2
transcription termination factor, RNA polymerase II
chr15_+_25773985 6.273 ENSMUST00000125667.1
 Myo10
myosin X
chr7_-_25788635 5.287 ENSMUST00000002677.4
ENSMUST00000085948.4
 Axl

AXL receptor tyrosine kinase

chr13_-_3893556 5.046 ENSMUST00000099946.4
 Net1
neuroepithelial cell transforming gene 1
chr11_+_101468164 4.764 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chrX_-_23266751 4.189 ENSMUST00000115316.2
 Klhl13
kelch-like 13
chr4_-_97584612 3.710 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_-_172043466 3.533 ENSMUST00000087950.3
 Cbln4
cerebellin 4 precursor protein
chr1_-_163289214 3.527 ENSMUST00000183691.1
 Prrx1
paired related homeobox 1
chr4_+_128993224 3.413 ENSMUST00000030583.6
ENSMUST00000102604.4
 Ak2

adenylate kinase 2

chr10_+_22158566 3.369 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr10_+_39133981 3.310 ENSMUST00000019991.7
 Tube1
epsilon-tubulin 1
chr3_-_79842662 3.224 ENSMUST00000029568.1
 Tmem144
transmembrane protein 144
chr11_-_64436653 3.151 ENSMUST00000177999.1
 F930015N05Rik
RIKEN cDNA F930015N05 gene
chr3_-_95217690 2.985 ENSMUST00000107209.1
 Gabpb2
GA repeat binding protein, beta 2
chr15_+_72913357 2.947 ENSMUST00000166418.2
 Gm3150
predicted gene 3150
chr17_-_40935047 2.796 ENSMUST00000087114.3
 Cenpq
centromere protein Q

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.3 19.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.5 15.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
1.6 11.5 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.4 7.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 6.3 GO:0022409 positive regulation of cell-cell adhesion(GO:0022409)
0.2 6.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.3 5.3 GO:2000668 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.3 5.0 GO:0051451 myoblast migration(GO:0051451)
0.5 4.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 4.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 4.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 3.8 GO:0000910 cytokinesis(GO:0000910)
0.3 3.7 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.3 3.5 GO:0048664 neuron fate determination(GO:0048664)
0.6 3.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.3 3.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 3.4 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.2 3.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 2.9 GO:0006821 chloride transport(GO:0006821)
0.6 2.6 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.9 15.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 10.6 GO:0005871 kinesin complex(GO:0005871)
0.1 7.9 GO:0030496 midbody(GO:0030496)
0.0 7.4 GO:0005681 spliceosomal complex(GO:0005681)
0.3 5.3 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0 4.9 GO:0005874 microtubule(GO:0005874)
0.0 4.8 GO:0005769 early endosome(GO:0005769)
0.1 4.4 GO:0016459 myosin complex(GO:0016459)
0.1 4.0 GO:0030992 intraciliary transport particle B(GO:0030992)
1.1 3.4 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.7 3.4 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 3.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 2.6 GO:0031519 PcG protein complex(GO:0031519)
0.5 2.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 2.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.7 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.7 GO:0005884 actin filament(GO:0005884)
0.2 1.6 GO:0070187 telosome(GO:0070187)
0.1 1.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 17.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 17.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.7 10.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 7.9 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.1 6.3 GO:0030507 spectrin binding(GO:0030507)
0.1 6.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.5 5.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 5.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 4.7 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.1 4.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 4.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 3.5 GO:0071837 HMG box domain binding(GO:0071837)
0.4 3.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 3.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 3.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 3.2 GO:0000287 magnesium ion binding(GO:0000287)
0.5 3.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 2.9 GO:0005254 chloride channel activity(GO:0005254)
0.4 2.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 2.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)