Motif ID: Hmga1

Z-value: 1.096


Transcription factors associated with Hmga1:

Gene SymbolEntrez IDGene Name
Hmga1 ENSMUSG00000046711.9 Hmga1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga1mm10_v2_chr17_+_27556641_27556658-0.508.4e-06Click!


Activity profile for motif Hmga1.

activity profile for motif Hmga1


Sorted Z-values histogram for motif Hmga1

Sorted Z-values for motif Hmga1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 7.923 ENSMUST00000075312.3
Ttr
transthyretin
chr1_-_56978534 7.446 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr12_-_41485751 6.966 ENSMUST00000043884.4
Lrrn3
leucine rich repeat protein 3, neuronal
chr18_-_43059418 6.796 ENSMUST00000025377.7
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr1_+_17145357 6.755 ENSMUST00000026879.7
Gdap1
ganglioside-induced differentiation-associated-protein 1
chr18_+_37504264 6.650 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr17_+_3397189 6.577 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr1_-_126830632 6.452 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr12_+_52699297 6.446 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr4_+_101507947 6.349 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr12_-_108003594 6.217 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr6_-_13839916 6.090 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr5_-_103100054 6.086 ENSMUST00000112848.1
Mapk10
mitogen-activated protein kinase 10
chr13_-_84064772 6.076 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr18_+_37400845 6.051 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr19_+_26623419 6.043 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_33624587 6.016 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr10_+_123264076 6.006 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr18_+_37513652 5.522 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr11_-_42000284 5.439 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 141 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 14.4 GO:0007097 nuclear migration(GO:0007097)
0.3 11.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.1 10.3 GO:0071420 cellular response to histamine(GO:0071420)
0.1 10.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
1.6 7.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.4 7.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
2.6 7.7 GO:0007525 somatic muscle development(GO:0007525)
0.5 7.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.2 7.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.0 6.8 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.2 6.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
1.6 6.4 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
1.1 6.3 GO:0072318 clathrin coat disassembly(GO:0072318)
1.0 6.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
1.0 6.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 6.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 6.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 5.9 GO:0042384 cilium assembly(GO:0042384)
0.2 5.6 GO:0008053 mitochondrial fusion(GO:0008053)
1.8 5.3 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 25.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 21.3 GO:0042641 actomyosin(GO:0042641)
0.7 12.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.6 10.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.3 8.6 GO:0071565 nBAF complex(GO:0071565)
0.2 7.6 GO:0030131 clathrin adaptor complex(GO:0030131)
1.5 7.5 GO:0044316 cone cell pedicle(GO:0044316)
0.3 7.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 6.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.6 6.2 GO:0071439 clathrin complex(GO:0071439)
0.1 5.8 GO:0055037 recycling endosome(GO:0055037)
0.0 5.8 GO:0005770 late endosome(GO:0005770)
0.0 5.6 GO:0016607 nuclear speck(GO:0016607)
0.1 5.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 5.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 4.9 GO:0044295 axonal growth cone(GO:0044295)
1.6 4.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.5 4.7 GO:0000805 X chromosome(GO:0000805)
0.2 4.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 4.6 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 100 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.6 GO:0005057 receptor signaling protein activity(GO:0005057)
0.6 10.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 9.4 GO:0003779 actin binding(GO:0003779)
0.0 8.3 GO:0000287 magnesium ion binding(GO:0000287)
1.0 7.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.9 7.2 GO:0001618 virus receptor activity(GO:0001618)
0.2 6.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.8 6.4 GO:0043495 protein anchor(GO:0043495)
0.4 6.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 6.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 6.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.4 5.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 5.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.5 5.3 GO:0003680 AT DNA binding(GO:0003680)
0.9 5.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 4.7 GO:0038191 neuropilin binding(GO:0038191)
1.1 4.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 4.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 4.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 4.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)