Motif ID: Hmga1
Z-value: 1.096
Transcription factors associated with Hmga1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hmga1 | ENSMUSG00000046711.9 | Hmga1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hmga1 | mm10_v2_chr17_+_27556641_27556658 | -0.50 | 8.4e-06 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 7.7 | GO:0007525 | somatic muscle development(GO:0007525) |
| 1.8 | 5.3 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
| 1.6 | 6.4 | GO:0032512 | regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of cAMP-dependent protein kinase activity(GO:2000481) |
| 1.6 | 7.9 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 1.6 | 4.7 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 1.4 | 4.3 | GO:1902071 | positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
| 1.4 | 4.2 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
| 1.3 | 3.9 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
| 1.2 | 3.7 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
| 1.2 | 7.2 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 1.1 | 10.3 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 1.1 | 4.4 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 1.1 | 3.2 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 1.1 | 6.3 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
| 1.1 | 5.3 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 1.0 | 6.2 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
| 1.0 | 3.1 | GO:0007210 | serotonin receptor signaling pathway(GO:0007210) |
| 1.0 | 6.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 1.0 | 6.8 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
| 0.8 | 4.7 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.8 | 2.3 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
| 0.7 | 3.7 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
| 0.7 | 4.7 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
| 0.7 | 6.0 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.7 | 4.7 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.7 | 2.0 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 0.7 | 3.9 | GO:0032796 | uropod organization(GO:0032796) |
| 0.6 | 14.4 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.6 | 3.7 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.6 | 4.2 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.6 | 1.7 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.5 | 7.4 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.5 | 2.1 | GO:0044330 | canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 0.5 | 3.1 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.5 | 3.2 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.4 | 2.2 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.4 | 7.8 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.4 | 1.8 | GO:0007262 | STAT protein import into nucleus(GO:0007262) |
| 0.3 | 1.0 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.3 | 2.4 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.3 | 11.1 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.3 | 1.6 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.3 | 0.9 | GO:0071873 | response to norepinephrine(GO:0071873) |
| 0.3 | 1.5 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.3 | 1.2 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.3 | 1.1 | GO:0036216 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) |
| 0.3 | 0.8 | GO:1905154 | negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154) |
| 0.3 | 0.8 | GO:0043323 | positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.2 | 4.0 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.2 | 0.9 | GO:0042938 | dipeptide transport(GO:0042938) |
| 0.2 | 1.4 | GO:0046549 | retinal cone cell development(GO:0046549) |
| 0.2 | 1.4 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.2 | 0.8 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.2 | 0.6 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.2 | 5.6 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.2 | 1.8 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.2 | 0.8 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
| 0.2 | 1.4 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
| 0.2 | 1.9 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.2 | 1.7 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.2 | 1.1 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.2 | 6.8 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.2 | 2.9 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.2 | 1.1 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.1 | 1.8 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.1 | 3.2 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.1 | 2.6 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.1 | 0.7 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
| 0.1 | 0.4 | GO:0048388 | endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401) |
| 0.1 | 2.3 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
| 0.1 | 1.8 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 10.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.1 | 3.5 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.1 | 1.3 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.1 | 4.2 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
| 0.1 | 0.8 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.1 | 2.6 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.1 | 2.8 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
| 0.1 | 2.0 | GO:0006828 | manganese ion transport(GO:0006828) |
| 0.1 | 1.3 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.1 | 0.4 | GO:0072592 | oxygen metabolic process(GO:0072592) |
| 0.1 | 6.0 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 2.0 | GO:0008209 | androgen metabolic process(GO:0008209) |
| 0.1 | 0.6 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 0.4 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.1 | 3.2 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.1 | 0.9 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.1 | 1.1 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.1 | 4.0 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.1 | 1.3 | GO:0060065 | uterus development(GO:0060065) |
| 0.1 | 0.6 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.1 | 1.1 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.1 | 1.4 | GO:0032402 | melanosome transport(GO:0032402) pigment granule transport(GO:0051904) |
| 0.1 | 0.4 | GO:0019695 | choline metabolic process(GO:0019695) |
| 0.1 | 2.2 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.1 | 0.2 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.1 | 0.5 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.1 | 1.0 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 1.8 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 1.9 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.1 | 0.5 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.1 | 0.3 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.1 | 3.9 | GO:0060349 | bone morphogenesis(GO:0060349) |
| 0.1 | 0.2 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 0.1 | 3.1 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.1 | 0.3 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.1 | 1.0 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.0 | 0.3 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.0 | 0.4 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.0 | 3.5 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.0 | 0.7 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
| 0.0 | 3.6 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 1.5 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.0 | 0.7 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.5 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.0 | 4.1 | GO:0098792 | xenophagy(GO:0098792) |
| 0.0 | 0.7 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.0 | 0.4 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.0 | 0.6 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 5.9 | GO:0042384 | cilium assembly(GO:0042384) |
| 0.0 | 1.0 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.6 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.0 | 2.9 | GO:0030048 | actin filament-based movement(GO:0030048) |
| 0.0 | 0.4 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 0.0 | 0.5 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.0 | 0.2 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.0 | 0.6 | GO:0070841 | inclusion body assembly(GO:0070841) |
| 0.0 | 0.3 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 0.3 | GO:0042733 | embryonic digit morphogenesis(GO:0042733) |
| 0.0 | 0.1 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.0 | 0.5 | GO:0008333 | endosome to lysosome transport(GO:0008333) vesicle-mediated transport between endosomal compartments(GO:0098927) |
| 0.0 | 0.1 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.0 | 0.2 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 1.1 | GO:0090003 | regulation of establishment of protein localization to plasma membrane(GO:0090003) |
| 0.0 | 0.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 1.3 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.0 | 0.8 | GO:0030336 | negative regulation of cell migration(GO:0030336) |
| 0.0 | 0.4 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 0.3 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.0 | 0.8 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.7 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 1.5 | 7.5 | GO:0044316 | cone cell pedicle(GO:0044316) |
| 0.7 | 12.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.6 | 6.2 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.6 | 10.3 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.5 | 1.4 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
| 0.5 | 4.7 | GO:0000805 | X chromosome(GO:0000805) |
| 0.4 | 3.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.4 | 6.4 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.3 | 8.6 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.3 | 2.0 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.3 | 3.2 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.3 | 7.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.2 | 3.1 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.2 | 7.6 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.2 | 4.7 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 21.3 | GO:0042641 | actomyosin(GO:0042641) |
| 0.2 | 1.9 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.1 | 1.2 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.1 | 1.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.1 | 1.9 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.1 | 1.1 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.1 | 3.6 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 4.3 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 4.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 0.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 1.4 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 4.2 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 1.0 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 1.9 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 3.7 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.1 | 0.6 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.1 | 2.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 3.1 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 3.3 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.1 | 5.4 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.1 | 1.0 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.1 | 25.0 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.1 | 2.4 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 0.4 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 4.6 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 5.4 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.1 | 3.4 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 1.1 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 5.8 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 0.5 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 2.4 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.7 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.3 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.0 | 5.8 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 0.6 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 0.7 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.0 | 5.6 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 2.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 1.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.7 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 2.4 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 0.9 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 1.9 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 2.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.1 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.0 | 1.1 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 2.3 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 1.5 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 2.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.7 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.4 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 1.8 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 1.8 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 1.2 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 1.1 | GO:0005769 | early endosome(GO:0005769) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.5 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 1.1 | 4.4 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 1.0 | 3.1 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 1.0 | 7.9 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.9 | 7.2 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.9 | 5.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.8 | 6.4 | GO:0043495 | protein anchor(GO:0043495) |
| 0.8 | 3.1 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589) |
| 0.6 | 3.5 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.6 | 10.3 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.5 | 3.2 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
| 0.5 | 2.6 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.5 | 5.3 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.5 | 1.9 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.5 | 1.4 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.5 | 3.6 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.4 | 4.7 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.4 | 5.6 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.4 | 3.9 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.4 | 5.8 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.4 | 6.1 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.3 | 2.0 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.3 | 2.3 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.3 | 4.0 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.3 | 0.9 | GO:0004335 | galactokinase activity(GO:0004335) |
| 0.3 | 3.7 | GO:0005522 | profilin binding(GO:0005522) |
| 0.3 | 4.0 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.3 | 1.0 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.3 | 6.0 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.2 | 3.3 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.2 | 1.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.2 | 0.6 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.2 | 0.9 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
| 0.2 | 6.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.2 | 2.0 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.2 | 3.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.2 | 1.7 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 2.6 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 1.3 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.1 | 3.1 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.1 | 0.4 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.1 | 1.2 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 1.5 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.1 | 1.4 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.1 | 3.7 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 3.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 1.5 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.1 | 2.1 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 4.2 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 2.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 3.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 0.5 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 1.2 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.1 | 0.4 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 3.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 4.3 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 12.6 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
| 0.1 | 0.8 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 1.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.2 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
| 0.1 | 0.5 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.1 | 0.5 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 1.8 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 0.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 1.3 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.1 | 4.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 0.4 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 2.2 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 6.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.6 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 1.1 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.8 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.0 | 0.2 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.0 | 8.3 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 0.4 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
| 0.0 | 1.2 | GO:0034945 | dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595) |
| 0.0 | 1.2 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 1.4 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 1.1 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.8 | GO:0051537 | ferrous iron binding(GO:0008198) 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 2.3 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.8 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 0.6 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 4.1 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.0 | 0.2 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.0 | 9.4 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 2.2 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.8 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.7 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.9 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.0 | 1.4 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA methyltransferase activity(GO:0008649) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) rRNA (uridine) methyltransferase activity(GO:0016436) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
| 0.0 | 1.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.8 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.1 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.0 | 0.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.5 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 1.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.3 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) DNA-N1-methyladenine dioxygenase activity(GO:0043734) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
| 0.0 | 0.2 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
