Motif ID: Hmga2

Z-value: 1.098


Transcription factors associated with Hmga2:

Gene SymbolEntrez IDGene Name
Hmga2 ENSMUSG00000056758.8 Hmga2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_120476527-0.311.0e-02Click!


Activity profile for motif Hmga2.

activity profile for motif Hmga2


Sorted Z-values histogram for motif Hmga2

Sorted Z-values for motif Hmga2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga2

PNG image of the network

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Top targets:


Showing 1 to 20 of 156 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3013140 10.831 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr2_-_98667264 10.703 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr14_-_19418930 10.131 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3004457 8.615 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3023547 7.171 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3025417 6.902 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3018753 6.301 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr9_+_3017408 6.044 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_-_123260776 4.572 ENSMUST00000068140.4
 Tmem158
transmembrane protein 158
chr5_+_14514918 4.559 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr4_+_44756553 3.576 ENSMUST00000107824.2
 Zcchc7
zinc finger, CCHC domain containing 7
chr2_-_148732457 3.466 ENSMUST00000028926.6
 Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr16_+_96361749 3.356 ENSMUST00000000163.6
ENSMUST00000081093.3
ENSMUST00000113795.1
 Igsf5


immunoglobulin superfamily, member 5


chr2_+_158375638 3.186 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr19_-_5510467 2.837 ENSMUST00000070172.4
 Snx32
sorting nexin 32
chr4_+_44756609 2.816 ENSMUST00000143385.1
 Zcchc7
zinc finger, CCHC domain containing 7
chrX_+_101640056 2.716 ENSMUST00000119299.1
ENSMUST00000044475.4
 Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr2_+_29124106 2.624 ENSMUST00000129544.1
 Setx
senataxin
chr14_-_36919314 2.541 ENSMUST00000182797.1
 Ccser2
coiled-coil serine rich 2
chr16_-_43979050 2.447 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.8 4.6 GO:0016080 synaptic vesicle targeting(GO:0016080)
1.3 3.8 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 3.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.5 2.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 2.6 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 2.4 GO:0018345 protein palmitoylation(GO:0018345)
0.2 2.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 2.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.2 2.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 2.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 1.7 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.2 1.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.5 1.4 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) positive regulation of cortisol secretion(GO:0051464)
0.0 1.4 GO:0034605 cellular response to heat(GO:0034605)
0.3 1.3 GO:0042938 dipeptide transport(GO:0042938)
0.2 1.3 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1 1.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 4.6 GO:0044316 cone cell pedicle(GO:0044316)
0.0 4.0 GO:0005923 bicellular tight junction(GO:0005923)
0.7 3.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 3.5 GO:0030426 growth cone(GO:0030426)
0.0 3.4 GO:0070469 respiratory chain(GO:0070469)
0.0 2.8 GO:0019898 extrinsic component of membrane(GO:0019898)
0.3 2.7 GO:0070688 MLL5-L complex(GO:0070688)
0.2 2.6 GO:0032584 growth cone membrane(GO:0032584)
0.0 2.6 GO:0000139 Golgi membrane(GO:0000139)
0.1 2.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 2.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.2 GO:0030496 midbody(GO:0030496)
0.2 1.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 1.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.7 GO:0005770 late endosome(GO:0005770)
0.2 1.3 GO:0089701 U2AF(GO:0089701)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 1.0 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.9 GO:0008017 microtubule binding(GO:0008017)
0.4 4.6 GO:0005522 profilin binding(GO:0005522)
0.1 3.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.9 3.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 3.4 GO:0030165 PDZ domain binding(GO:0030165)
0.9 2.7 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.9 2.6 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 2.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 2.3 GO:0030276 clathrin binding(GO:0030276)
0.6 2.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 1.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 1.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 1.3 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)