Motif ID: Hmx2

Z-value: 0.498


Transcription factors associated with Hmx2:

Gene SymbolEntrez IDGene Name
Hmx2 ENSMUSG00000050100.7 Hmx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx2mm10_v2_chr7_+_131548755_131548773-0.152.1e-01Click!


Activity profile for motif Hmx2.

activity profile for motif Hmx2


Sorted Z-values histogram for motif Hmx2

Sorted Z-values for motif Hmx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_48667508 1.520 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr5_-_28467093 1.437 ENSMUST00000002708.3
Shh
sonic hedgehog
chr12_+_72441852 1.337 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr6_-_137169710 1.110 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr6_-_137169678 1.033 ENSMUST00000119610.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr5_-_28210022 0.889 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chrM_+_7759 0.791 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr15_-_42676967 0.761 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr18_-_65939048 0.742 ENSMUST00000025396.3
Rax
retina and anterior neural fold homeobox
chr19_-_58454435 0.695 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr5_+_8660059 0.678 ENSMUST00000047753.4
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr7_-_37772868 0.673 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr14_+_73237891 0.665 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr18_-_34579072 0.658 ENSMUST00000079287.5
Nme5
NME/NM23 family member 5
chr12_-_98901478 0.646 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr2_-_24048857 0.626 ENSMUST00000114497.1
Hnmt
histamine N-methyltransferase
chr1_+_91298354 0.624 ENSMUST00000142488.1
ENSMUST00000124832.1
ENSMUST00000147523.1
Scly


selenocysteine lyase


chr6_+_29694204 0.617 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr13_-_92794809 0.613 ENSMUST00000022213.7
Thbs4
thrombospondin 4
chr4_-_62470868 0.603 ENSMUST00000135811.1
ENSMUST00000120095.1
ENSMUST00000030087.7
ENSMUST00000107452.1
ENSMUST00000155522.1
Wdr31




WD repeat domain 31




chr1_+_46066738 0.577 ENSMUST00000069293.7
Dnah7b
dynein, axonemal, heavy chain 7B
chr11_-_96977660 0.558 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2

Sp2 transcription factor

chr5_-_28210168 0.516 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr1_+_91298334 0.499 ENSMUST00000027532.6
Scly
selenocysteine lyase
chr13_-_59675754 0.486 ENSMUST00000022039.5
ENSMUST00000095739.2
Golm1

golgi membrane protein 1

chr18_+_50051702 0.471 ENSMUST00000134348.1
ENSMUST00000153873.2
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr3_+_109573907 0.470 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr4_+_99955715 0.460 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr11_-_3931960 0.457 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr4_+_94739276 0.453 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr9_-_37552904 0.452 ENSMUST00000065668.5
Nrgn
neurogranin
chr15_+_85510812 0.431 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr10_-_22149270 0.413 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr5_+_8893677 0.407 ENSMUST00000003717.8
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr3_+_19957037 0.406 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr18_-_88894322 0.400 ENSMUST00000070116.5
ENSMUST00000125362.1
Socs6

suppressor of cytokine signaling 6

chr13_-_71963713 0.400 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr11_-_100822525 0.397 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chrX_+_150594420 0.393 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_-_24049389 0.392 ENSMUST00000051416.5
Hnmt
histamine N-methyltransferase
chr3_-_65392546 0.384 ENSMUST00000119896.1
Ssr3
signal sequence receptor, gamma
chr1_-_172632931 0.380 ENSMUST00000027826.5
Dusp23
dual specificity phosphatase 23
chr4_+_90218820 0.351 ENSMUST00000107129.1
Zfp352
zinc finger protein 352
chr10_+_128908907 0.349 ENSMUST00000105229.1
Cd63
CD63 antigen
chr3_-_65392579 0.342 ENSMUST00000029414.5
Ssr3
signal sequence receptor, gamma
chr19_-_46969474 0.339 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr18_-_31911903 0.326 ENSMUST00000054984.6
Sft2d3
SFT2 domain containing 3
chr10_+_115569986 0.325 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr4_-_94603239 0.314 ENSMUST00000107107.2
Plaa
phospholipase A2, activating protein
chr5_+_23850590 0.307 ENSMUST00000181574.1
2700038G22Rik
RIKEN cDNA 2700038G22 gene
chr18_-_66022580 0.304 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr4_-_132398199 0.297 ENSMUST00000136711.1
ENSMUST00000084249.4
Phactr4

phosphatase and actin regulator 4

chr4_-_26346882 0.290 ENSMUST00000041374.7
ENSMUST00000153813.1
Manea

mannosidase, endo-alpha

chr8_-_22694061 0.284 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chrX_+_112615301 0.283 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr4_+_122836236 0.274 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
Ppt1


palmitoyl-protein thioesterase 1


chr5_-_138272733 0.271 ENSMUST00000161665.1
ENSMUST00000100530.1
Gal3st4

galactose-3-O-sulfotransferase 4

chr9_-_122310921 0.265 ENSMUST00000180685.1
Gm26797
predicted gene, 26797
chr8_-_8690493 0.261 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chr17_+_35841668 0.259 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr16_+_17619341 0.256 ENSMUST00000006053.6
ENSMUST00000171435.1
ENSMUST00000163476.1
ENSMUST00000168101.1
ENSMUST00000165363.1
ENSMUST00000169662.1
ENSMUST00000090159.4
ENSMUST00000172182.1
ENSMUST00000163592.1
Smpd4








sphingomyelin phosphodiesterase 4








chr10_+_121365078 0.248 ENSMUST00000040344.6
Gns
glucosamine (N-acetyl)-6-sulfatase
chr2_-_9878580 0.244 ENSMUST00000102976.3
Gata3
GATA binding protein 3
chr1_+_109993982 0.244 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr2_+_167421706 0.244 ENSMUST00000047815.6
ENSMUST00000109218.1
ENSMUST00000073873.3
Slc9a8


solute carrier family 9 (sodium/hydrogen exchanger), member 8


chr14_+_48446128 0.238 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr10_+_69925800 0.234 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr2_-_33087169 0.234 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr16_+_36934976 0.231 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr3_+_124321031 0.228 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr10_+_63061582 0.228 ENSMUST00000020266.8
ENSMUST00000178684.1
Pbld1

phenazine biosynthesis-like protein domain containing 1

chr18_+_4993795 0.225 ENSMUST00000153016.1
Svil
supervillin
chr4_-_96553617 0.223 ENSMUST00000030303.5
Cyp2j6
cytochrome P450, family 2, subfamily j, polypeptide 6
chr9_-_50739365 0.218 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr8_+_71922810 0.217 ENSMUST00000119003.1
Zfp617
zinc finger protein 617
chr14_+_48446340 0.215 ENSMUST00000111735.2
Tmem260
transmembrane protein 260
chr8_-_110902442 0.215 ENSMUST00000041382.6
Fuk
fucokinase
chrX_-_164027965 0.209 ENSMUST00000033739.4
Car5b
carbonic anhydrase 5b, mitochondrial
chr4_-_99829180 0.208 ENSMUST00000146258.1
Itgb3bp
integrin beta 3 binding protein (beta3-endonexin)
chr3_+_66985947 0.204 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr3_+_84952146 0.190 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr3_+_106721672 0.186 ENSMUST00000098750.2
ENSMUST00000130105.1
Lrif1

ligand dependent nuclear receptor interacting factor 1

chr10_+_24869998 0.182 ENSMUST00000020159.8
Med23
mediator complex subunit 23
chr5_-_31526693 0.182 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
Supt7l


suppressor of Ty 7-like


chr17_-_53539411 0.177 ENSMUST00000056198.3
Pp2d1
protein phosphatase 2C-like domain containing 1
chr4_+_147492417 0.171 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr11_+_107479549 0.169 ENSMUST00000106750.4
Psmd12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr10_+_69925766 0.168 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr10_+_77613709 0.167 ENSMUST00000124024.2
Sumo3
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr1_-_57970104 0.164 ENSMUST00000114410.3
Kctd18
potassium channel tetramerisation domain containing 18
chr1_-_57970067 0.164 ENSMUST00000164963.1
Kctd18
potassium channel tetramerisation domain containing 18
chr14_-_52213379 0.161 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr1_-_37536232 0.158 ENSMUST00000042161.8
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr5_-_140830430 0.157 ENSMUST00000000153.4
Gna12
guanine nucleotide binding protein, alpha 12
chr10_-_19907645 0.156 ENSMUST00000166511.1
ENSMUST00000020182.8
Pex7

peroxisomal biogenesis factor 7

chrX_+_164373363 0.155 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr2_-_33086366 0.152 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr5_+_15516489 0.151 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr14_-_104522615 0.149 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr4_-_128962420 0.146 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
Adc


arginine decarboxylase


chr9_-_15279860 0.145 ENSMUST00000034411.8
Med17
mediator complex subunit 17
chr18_+_62977854 0.145 ENSMUST00000150267.1
Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr16_-_14291355 0.142 ENSMUST00000090287.3
Myh11
myosin, heavy polypeptide 11, smooth muscle
chrX_-_56598069 0.138 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr4_+_133574728 0.132 ENSMUST00000030662.2
Gpatch3
G patch domain containing 3
chr12_+_8973892 0.132 ENSMUST00000085745.6
ENSMUST00000111113.2
Wdr35

WD repeat domain 35

chr10_-_127311740 0.129 ENSMUST00000037290.5
ENSMUST00000171564.1
Mars

methionine-tRNA synthetase

chr6_-_113501818 0.128 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3
chr10_+_116143881 0.122 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr5_+_114380591 0.115 ENSMUST00000074002.5
Ube3b
ubiquitin protein ligase E3B
chr3_-_116712644 0.115 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr7_-_116084635 0.114 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr1_+_173420567 0.113 ENSMUST00000173023.1
Aim2
absent in melanoma 2
chr8_-_123318553 0.106 ENSMUST00000118395.1
ENSMUST00000035495.8
Fanca

Fanconi anemia, complementation group A

chr8_+_25017211 0.105 ENSMUST00000033961.5
Tm2d2
TM2 domain containing 2
chr1_+_164115264 0.098 ENSMUST00000162746.1
Selp
selectin, platelet
chr14_+_11227511 0.084 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr10_-_37138863 0.083 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr16_+_17619503 0.082 ENSMUST00000165092.1
Smpd4
sphingomyelin phosphodiesterase 4
chr1_-_180813534 0.078 ENSMUST00000159789.1
ENSMUST00000081026.4
H3f3a

H3 histone, family 3A

chr6_-_81965925 0.078 ENSMUST00000032124.8
Mrpl19
mitochondrial ribosomal protein L19
chr7_-_133123409 0.078 ENSMUST00000170459.1
ENSMUST00000166400.1
Ctbp2

C-terminal binding protein 2

chr11_-_78080360 0.075 ENSMUST00000021183.3
Eral1
Era (G-protein)-like 1 (E. coli)
chr8_-_105568298 0.075 ENSMUST00000005849.5
Agrp
agouti related protein
chr14_-_18893376 0.072 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr4_-_56947411 0.046 ENSMUST00000107609.3
ENSMUST00000068792.6
Tmem245

transmembrane protein 245

chrX_+_140367494 0.044 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr13_-_107022027 0.040 ENSMUST00000117539.1
ENSMUST00000122233.1
ENSMUST00000022204.9
ENSMUST00000159772.1
Kif2a



kinesin family member 2A



chr5_-_114380459 0.037 ENSMUST00000001125.5
Kctd10
potassium channel tetramerisation domain containing 10
chr7_+_3645267 0.037 ENSMUST00000038913.9
Cnot3
CCR4-NOT transcription complex, subunit 3
chr17_+_48346465 0.035 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chrX_+_38600626 0.034 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr7_-_43505926 0.033 ENSMUST00000013497.1
ENSMUST00000163619.1
4931406B18Rik

RIKEN cDNA 4931406B18 gene

chr6_+_40471352 0.029 ENSMUST00000114779.2
ENSMUST00000031971.6
ENSMUST00000121360.1
ENSMUST00000117411.1
ENSMUST00000117830.1
Ssbp1




single-stranded DNA binding protein 1




chr11_+_58171648 0.027 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr7_-_133123770 0.026 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2

chr2_-_26933781 0.025 ENSMUST00000154651.1
ENSMUST00000015011.3
Surf4

surfeit gene 4

chr14_-_19823807 0.024 ENSMUST00000022341.5
2700060E02Rik
RIKEN cDNA 2700060E02 gene
chr15_+_102407144 0.019 ENSMUST00000169619.1
Sp1
trans-acting transcription factor 1
chr2_-_164071124 0.016 ENSMUST00000109384.3
Tomm34
translocase of outer mitochondrial membrane 34
chr5_-_20951769 0.013 ENSMUST00000036489.5
Rsbn1l
round spermatid basic protein 1-like
chr2_-_164071089 0.012 ENSMUST00000018466.3
Tomm34
translocase of outer mitochondrial membrane 34
chr9_-_113708209 0.008 ENSMUST00000111861.3
ENSMUST00000035086.6
Pdcd6ip

programmed cell death 6 interacting protein

chr1_+_164275559 0.006 ENSMUST00000027867.6
Ccdc181
coiled-coil domain containing 181
chr7_-_78783026 0.006 ENSMUST00000032841.5
Mrpl46
mitochondrial ribosomal protein L46
chr2_+_30392405 0.005 ENSMUST00000113612.3
ENSMUST00000123202.1
Dolpp1

dolichyl pyrophosphate phosphatase 1

chr2_-_127444524 0.003 ENSMUST00000028848.3
Fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chrX_-_75578188 0.002 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.4 1.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 1.5 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 0.7 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.2 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 1.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.4 GO:0045472 response to ether(GO:0045472)
0.1 0.4 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.2 GO:0035799 ureter maturation(GO:0035799) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 0.3 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 0.7 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.3 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.7 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.5 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.5 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945) negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.5 GO:0032611 interleukin-1 beta production(GO:0032611)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.2 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0001740 Barr body(GO:0001740)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0043237 laminin-1 binding(GO:0043237)
0.2 1.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 1.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.3 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0070330 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) aromatase activity(GO:0070330)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)