Motif ID: Hmx3

Z-value: 0.275


Transcription factors associated with Hmx3:

Gene SymbolEntrez IDGene Name
Hmx3 ENSMUSG00000040148.5 Hmx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx3mm10_v2_chr7_+_131542867_1315428670.133.0e-01Click!


Activity profile for motif Hmx3.

activity profile for motif Hmx3


Sorted Z-values histogram for motif Hmx3

Sorted Z-values for motif Hmx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 62 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_49757257 1.287 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr3_-_154328634 0.855 ENSMUST00000167744.1
 Lhx8
LIM homeobox protein 8
chr13_+_118714678 0.847 ENSMUST00000022246.8
 Fgf10
fibroblast growth factor 10
chr13_-_92131494 0.764 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr10_+_99263224 0.727 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr9_-_123678782 0.595 ENSMUST00000170591.1
ENSMUST00000171647.1
 Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr5_+_15516489 0.491 ENSMUST00000178227.1
 Gm21847
predicted gene, 21847
chr2_+_3114220 0.479 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr9_-_123678873 0.468 ENSMUST00000040960.6
 Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr2_-_72986716 0.464 ENSMUST00000112062.1
 Gm11084
predicted gene 11084
chrX_+_150594420 0.460 ENSMUST00000112713.2
 Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr4_-_62470868 0.447 ENSMUST00000135811.1
ENSMUST00000120095.1
ENSMUST00000030087.7
ENSMUST00000107452.1
ENSMUST00000155522.1
 Wdr31




WD repeat domain 31




chr18_+_61639542 0.390 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr11_+_103133303 0.378 ENSMUST00000107037.1
 Hexim2
hexamethylene bis-acetamide inducible 2
chr4_-_129261394 0.357 ENSMUST00000145261.1
 C77080
expressed sequence C77080
chr5_-_137684665 0.354 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
 Agfg2


ArfGAP with FG repeats 2


chr7_-_126897424 0.323 ENSMUST00000120007.1
 Tmem219
transmembrane protein 219
chr5_-_87482258 0.307 ENSMUST00000079811.6
ENSMUST00000144144.1
 Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr7_+_3645267 0.284 ENSMUST00000038913.9
 Cnot3
CCR4-NOT transcription complex, subunit 3
chr11_+_114668524 0.279 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
 Rpl38



ribosomal protein L38




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.1 GO:0036233 glycine import(GO:0036233)
0.0 0.9 GO:0021884 forebrain neuron development(GO:0021884)
0.3 0.8 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.8 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.2 0.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.6 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.3 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.2 GO:0030862 neuroblast division in subventricular zone(GO:0021849) regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 0.2 GO:1903265 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 0.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)