Motif ID: Hnf1a

Z-value: 0.508


Transcription factors associated with Hnf1a:

Gene SymbolEntrez IDGene Name
Hnf1a ENSMUSG00000029556.6 Hnf1a



Activity profile for motif Hnf1a.

activity profile for motif Hnf1a


Sorted Z-values histogram for motif Hnf1a

Sorted Z-values for motif Hnf1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf1a

PNG image of the network

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Top targets:


Showing 1 to 20 of 59 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_144751968 4.153 ENSMUST00000155175.1
 Ano1
anoctamin 1, calcium activated chloride channel
chr13_-_53286052 3.619 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr19_-_14598031 3.099 ENSMUST00000167776.2
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr9_+_99629496 3.089 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
 Dzip1l


DAZ interacting protein 1-like


chr9_-_106158109 2.823 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chr19_-_14597983 2.613 ENSMUST00000052011.7
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr10_-_30842765 2.395 ENSMUST00000019924.8
 Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr11_+_78178105 2.367 ENSMUST00000147819.1
 Tlcd1
TLC domain containing 1
chr5_+_8046077 2.193 ENSMUST00000088786.4
 Sri
sorcin
chr9_+_99629823 2.113 ENSMUST00000112886.2
 Dzip1l
DAZ interacting protein 1-like
chr2_-_68472138 1.969 ENSMUST00000102715.3
 Stk39
serine/threonine kinase 39
chr5_+_24428208 1.854 ENSMUST00000115049.2
 Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr11_+_3983704 1.780 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr11_+_3983636 1.770 ENSMUST00000078757.1
 Gal3st1
galactose-3-O-sulfotransferase 1
chr17_+_71204647 1.631 ENSMUST00000126681.1
 Lpin2
lipin 2
chr9_+_53771499 1.612 ENSMUST00000048670.8
 Slc35f2
solute carrier family 35, member F2
chr10_+_87859062 1.561 ENSMUST00000095360.4
 Igf1
insulin-like growth factor 1
chr7_-_79842287 1.543 ENSMUST00000049004.6
 Anpep
alanyl (membrane) aminopeptidase
chr10_+_87859255 1.524 ENSMUST00000105300.2
 Igf1
insulin-like growth factor 1
chr19_-_47919269 1.303 ENSMUST00000095998.5
 Itprip
inositol 1,4,5-triphosphate receptor interacting protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.2 GO:0042384 cilium assembly(GO:0042384)
0.8 4.2 GO:0015705 iodide transport(GO:0015705)
0.7 3.6 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
1.2 3.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.0 3.1 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.8 2.4 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3 2.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.3 2.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.7 2.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.3 2.0 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 1.9 GO:0006821 chloride transport(GO:0006821)
0.0 1.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 1.5 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 1.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 1.3 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 1.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2 1.1 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.3 1.0 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 GO:0005814 centriole(GO:0005814)
0.0 5.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 4.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 4.1 GO:0000139 Golgi membrane(GO:0000139)
0.8 3.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 2.4 GO:0016580 Sin3 complex(GO:0016580)
0.7 2.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 2.0 GO:0008021 synaptic vesicle(GO:0008021)
0.5 1.5 GO:0031983 vesicle lumen(GO:0031983)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 1.0 GO:0030133 transport vesicle(GO:0030133)
0.2 0.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.7 GO:0070491 repressing transcription factor binding(GO:0070491)
1.0 4.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 3.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.9 3.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 3.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.8 2.4 GO:0035939 microsatellite binding(GO:0035939)
0.1 2.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 2.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.5 2.0 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.0 2.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 1.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.5 1.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.3 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 1.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.1 GO:0015265 urea channel activity(GO:0015265)
0.1 1.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)