Motif ID: Hnf1b

Z-value: 0.740


Transcription factors associated with Hnf1b:

Gene SymbolEntrez IDGene Name
Hnf1b ENSMUSG00000020679.5 Hnf1b



Activity profile for motif Hnf1b.

activity profile for motif Hnf1b


Sorted Z-values histogram for motif Hnf1b

Sorted Z-values for motif Hnf1b



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf1b

PNG image of the network

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Top targets:


Showing 1 to 20 of 113 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_53286052 8.616 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr10_-_7212222 8.143 ENSMUST00000015346.5
 Cnksr3
Cnksr family member 3
chr7_-_144751968 6.741 ENSMUST00000155175.1
 Ano1
anoctamin 1, calcium activated chloride channel
chr3_+_154597352 6.148 ENSMUST00000140644.1
ENSMUST00000144764.1
ENSMUST00000155232.1
 Cryz


crystallin, zeta


chr4_-_106464167 5.915 ENSMUST00000049507.5
 Pcsk9
proprotein convertase subtilisin/kexin type 9
chrX_+_52791179 5.739 ENSMUST00000101588.1
 Ccdc160
coiled-coil domain containing 160
chr4_-_134767940 5.703 ENSMUST00000037828.6
 Ldlrap1
low density lipoprotein receptor adaptor protein 1
chr11_-_76027726 5.476 ENSMUST00000021207.6
 Fam101b
family with sequence similarity 101, member B
chr2_+_158768083 5.467 ENSMUST00000029183.2
 Fam83d
family with sequence similarity 83, member D
chr9_-_106158109 5.302 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chr9_+_99629496 5.245 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
 Dzip1l


DAZ interacting protein 1-like


chr14_+_46882854 4.867 ENSMUST00000022386.8
ENSMUST00000100672.3
 Samd4

sterile alpha motif domain containing 4

chr17_+_47737030 4.793 ENSMUST00000086932.3
 Tfeb
transcription factor EB
chr3_-_150073620 4.779 ENSMUST00000057740.5
 Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr13_+_89540636 4.714 ENSMUST00000022108.7
 Hapln1
hyaluronan and proteoglycan link protein 1
chr9_+_15520830 4.628 ENSMUST00000178999.1
 Smco4
single-pass membrane protein with coiled-coil domains 4
chr9_+_99629823 4.438 ENSMUST00000112886.2
 Dzip1l
DAZ interacting protein 1-like
chr3_-_138131356 4.145 ENSMUST00000029805.8
 Mttp
microsomal triglyceride transfer protein
chr10_+_61089327 4.084 ENSMUST00000020298.6
 Pcbd1
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1
chr19_+_23723279 4.036 ENSMUST00000067077.1
 Gm9938
predicted gene 9938

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 8.6 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 8.1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
2.2 6.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.3 6.7 GO:0015705 iodide transport(GO:0015705)
0.4 6.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
2.0 5.9 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.5 5.7 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
1.8 5.5 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 5.5 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
1.7 5.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 4.9 GO:0045727 positive regulation of translation(GO:0045727)
0.1 4.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.8 4.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.5 4.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.8 4.0 GO:0072757 cellular response to camptothecin(GO:0072757)
0.0 3.8 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 3.8 GO:0042384 cilium assembly(GO:0042384)
1.2 3.5 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3 3.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 3.5 GO:0006825 copper ion transport(GO:0006825)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.7 GO:0005814 centriole(GO:0005814)
0.0 7.8 GO:0005667 transcription factor complex(GO:0005667)
0.2 6.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 6.2 GO:0000139 Golgi membrane(GO:0000139)
2.0 5.9 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
1.4 5.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.5 5.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 5.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 5.1 GO:0031143 pseudopodium(GO:0031143)
0.0 4.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 4.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 3.8 GO:0043034 costamere(GO:0043034)
0.2 3.5 GO:0016580 Sin3 complex(GO:0016580)
0.2 3.3 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.2 3.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 3.0 GO:0010369 chromocenter(GO:0010369)
0.9 2.8 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 2.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 7.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.7 6.7 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.7 6.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 6.1 GO:0070402 NADPH binding(GO:0070402)
2.0 5.9 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.6 5.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 5.5 GO:0031005 filamin binding(GO:0031005)
0.1 5.5 GO:0019894 kinesin binding(GO:0019894)
0.1 5.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 5.2 GO:0030371 translation repressor activity(GO:0030371)
0.1 5.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.3 4.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 4.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 3.8 GO:0051015 actin filament binding(GO:0051015)
1.2 3.5 GO:0035939 microsatellite binding(GO:0035939)
0.2 3.3 GO:0005537 mannose binding(GO:0005537)
0.2 3.3 GO:0008143 poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266)
0.8 3.1 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.2 3.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)