Motif ID: Homez

Z-value: 0.593


Transcription factors associated with Homez:

Gene SymbolEntrez IDGene Name
Homez ENSMUSG00000057156.9 Homez

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Homezmm10_v2_chr14_-_54864055_548641580.335.5e-03Click!


Activity profile for motif Homez.

activity profile for motif Homez


Sorted Z-values histogram for motif Homez

Sorted Z-values for motif Homez



Network of associatons between targets according to the STRING database.



First level regulatory network of Homez

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 7.839 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_-_117178726 7.556 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr4_+_44300876 6.042 ENSMUST00000045607.5
Melk
maternal embryonic leucine zipper kinase
chr11_+_101627942 4.785 ENSMUST00000010506.3
Rdm1
RAD52 motif 1
chr8_-_4779513 4.674 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr18_+_50030977 4.030 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr8_+_116921735 4.027 ENSMUST00000034205.4
Cenpn
centromere protein N
chr16_-_26989974 3.761 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr3_+_90220783 3.751 ENSMUST00000065418.6
Rab13
RAB13, member RAS oncogene family
chr6_+_137754529 3.586 ENSMUST00000087675.6
Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr17_+_87635974 3.525 ENSMUST00000053577.8
Epcam
epithelial cell adhesion molecule
chr8_-_72305276 3.286 ENSMUST00000075602.6
Gm10282
predicted pseudogene 10282
chr2_+_71389239 3.257 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr7_+_67647405 3.247 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr1_-_20820213 3.098 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr17_+_24426676 3.015 ENSMUST00000024946.5
Eci1
enoyl-Coenzyme A delta isomerase 1
chr7_-_62464505 2.889 ENSMUST00000094339.2
Peg12
paternally expressed 12
chr9_-_36726374 2.737 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr19_-_30175414 2.714 ENSMUST00000025778.7
Gldc
glycine decarboxylase
chr9_+_91368811 2.659 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 7.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.5 7.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 6.5 GO:0006270 DNA replication initiation(GO:0006270)
0.1 6.0 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
1.2 4.8 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.0 4.8 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 4.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 4.0 GO:0034508 centromere complex assembly(GO:0034508)
0.6 3.8 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.9 3.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 3.6 GO:0032611 interleukin-1 beta production(GO:0032611)
0.9 3.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.7 3.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.1 3.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.5 3.1 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 3.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 2.9 GO:0000578 embryonic axis specification(GO:0000578)
0.7 2.8 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.9 2.7 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5 2.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.6 GO:0035371 microtubule plus-end(GO:0035371)
0.1 4.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 3.9 GO:0005938 cell cortex(GO:0005938)
0.2 3.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 3.7 GO:0000776 kinetochore(GO:0000776)
0.1 3.5 GO:0016328 lateral plasma membrane(GO:0016328)
1.1 3.2 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 3.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.2 3.1 GO:0042555 MCM complex(GO:0042555)
0.0 3.1 GO:0005657 replication fork(GO:0005657)
0.8 2.4 GO:1990423 RZZ complex(GO:1990423)
0.0 2.4 GO:0005902 microvillus(GO:0005902)
0.0 2.4 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 2.4 GO:0036064 ciliary basal body(GO:0036064)
0.3 2.3 GO:0070652 HAUS complex(GO:0070652)
0.2 2.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.2 GO:0005643 nuclear pore(GO:0005643)
0.3 2.1 GO:0071817 MMXD complex(GO:0071817)
0.5 1.9 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.4 1.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.5 7.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 6.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.2 6.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 4.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 4.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 4.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 4.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 3.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.4 3.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.2 3.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 3.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 3.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 3.1 GO:0008198 ferrous iron binding(GO:0008198)
0.1 3.1 GO:0070888 E-box binding(GO:0070888)
0.6 3.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.9 2.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 2.7 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 2.7 GO:0003678 DNA helicase activity(GO:0003678)
0.2 2.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)