Motif ID: Hoxa1

Z-value: 0.878


Transcription factors associated with Hoxa1:

Gene SymbolEntrez IDGene Name
Hoxa1 ENSMUSG00000029844.9 Hoxa1



Activity profile for motif Hoxa1.

activity profile for motif Hoxa1


Sorted Z-values histogram for motif Hoxa1

Sorted Z-values for motif Hoxa1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa1

PNG image of the network

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Top targets:


Showing 1 to 20 of 94 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_143299498 11.779 ENSMUST00000030317.7
Pdpn
podoplanin
chr9_+_15239045 8.130 ENSMUST00000034413.6
Vstm5
V-set and transmembrane domain containing 5
chr14_-_103844173 7.490 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr14_+_70077375 6.284 ENSMUST00000035908.1
Egr3
early growth response 3
chr7_+_73391160 5.910 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr2_+_163225363 5.737 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr4_-_143299463 4.584 ENSMUST00000119654.1
Pdpn
podoplanin
chr2_+_152962485 4.467 ENSMUST00000099197.2
ENSMUST00000103155.3
Ttll9

tubulin tyrosine ligase-like family, member 9

chr8_-_11312731 3.458 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr15_-_95528702 3.395 ENSMUST00000166170.1
Nell2
NEL-like 2
chr4_-_106799779 3.302 ENSMUST00000145061.1
ENSMUST00000102762.3
Acot11

acyl-CoA thioesterase 11

chr13_-_12340723 3.199 ENSMUST00000168193.1
ENSMUST00000110616.1
ENSMUST00000064204.7
Actn2


actinin alpha 2


chr10_+_79988584 3.128 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr15_+_74516196 3.021 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr13_-_60177357 2.968 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr10_+_94576254 2.582 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr8_-_117673682 2.167 ENSMUST00000173522.1
ENSMUST00000174450.1
Sdr42e1

short chain dehydrogenase/reductase family 42E, member 1

chr16_+_38902305 2.119 ENSMUST00000023478.7
Igsf11
immunoglobulin superfamily, member 11
chr6_-_52012476 2.073 ENSMUST00000078214.5
Skap2
src family associated phosphoprotein 2
chr3_+_68572245 1.965 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 16.4 GO:0010572 positive regulation of platelet activation(GO:0010572)
2.5 7.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.5 6.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.6 5.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.5 3.5 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 3.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.3 3.4 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 3.4 GO:0006631 fatty acid metabolic process(GO:0006631)
1.1 3.2 GO:0051695 actin filament uncapping(GO:0051695)
0.3 3.0 GO:0042473 outer ear morphogenesis(GO:0042473)
0.2 2.7 GO:0070842 aggresome assembly(GO:0070842)
0.0 2.3 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 2.1 GO:0002757 immune response-activating signal transduction(GO:0002757)
0.1 2.0 GO:0001553 luteinization(GO:0001553)
0.0 1.9 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 1.8 GO:0042711 maternal behavior(GO:0042711)
0.5 1.4 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.5 1.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.2 1.4 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.2 1.3 GO:0015808 L-alanine transport(GO:0015808)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 18.4 GO:0030175 filopodium(GO:0030175)
0.0 6.2 GO:0031965 nuclear membrane(GO:0031965)
0.2 4.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.7 3.5 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 3.4 GO:0043204 perikaryon(GO:0043204)
0.0 3.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.9 GO:0043034 costamere(GO:0043034)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.7 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 16.4 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
2.5 7.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.5 5.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 5.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 3.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 3.4 GO:0005080 protein kinase C binding(GO:0005080)
0.2 3.3 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.4 3.2 GO:0031432 thyroid hormone receptor coactivator activity(GO:0030375) titin binding(GO:0031432)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.4 2.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 2.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.9 GO:0051015 actin filament binding(GO:0051015)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 1.3 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 1.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)