Motif ID: Hoxa1

Z-value: 0.878


Transcription factors associated with Hoxa1:

Gene SymbolEntrez IDGene Name
Hoxa1 ENSMUSG00000029844.9 Hoxa1



Activity profile for motif Hoxa1.

activity profile for motif Hoxa1


Sorted Z-values histogram for motif Hoxa1

Sorted Z-values for motif Hoxa1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_143299498 11.779 ENSMUST00000030317.7
 Pdpn
podoplanin
chr9_+_15239045 8.130 ENSMUST00000034413.6
 Vstm5
V-set and transmembrane domain containing 5
chr14_-_103844173 7.490 ENSMUST00000022718.3
 Ednrb
endothelin receptor type B
chr14_+_70077375 6.284 ENSMUST00000035908.1
 Egr3
early growth response 3
chr7_+_73391160 5.910 ENSMUST00000128471.1
 Rgma
RGM domain family, member A
chr2_+_163225363 5.737 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr4_-_143299463 4.584 ENSMUST00000119654.1
 Pdpn
podoplanin
chr2_+_152962485 4.467 ENSMUST00000099197.2
ENSMUST00000103155.3
 Ttll9

tubulin tyrosine ligase-like family, member 9

chr8_-_11312731 3.458 ENSMUST00000033898.9
 Col4a1
collagen, type IV, alpha 1
chr15_-_95528702 3.395 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr4_-_106799779 3.302 ENSMUST00000145061.1
ENSMUST00000102762.3
 Acot11

acyl-CoA thioesterase 11

chr13_-_12340723 3.199 ENSMUST00000168193.1
ENSMUST00000110616.1
ENSMUST00000064204.7
 Actn2


actinin alpha 2


chr10_+_79988584 3.128 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr15_+_74516196 3.021 ENSMUST00000042035.9
 Bai1
brain-specific angiogenesis inhibitor 1
chr13_-_60177357 2.968 ENSMUST00000065086.4
 Gas1
growth arrest specific 1
chr10_+_94576254 2.582 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chr8_-_117673682 2.167 ENSMUST00000173522.1
ENSMUST00000174450.1
 Sdr42e1

short chain dehydrogenase/reductase family 42E, member 1

chr16_+_38902305 2.119 ENSMUST00000023478.7
 Igsf11
immunoglobulin superfamily, member 11
chr6_-_52012476 2.073 ENSMUST00000078214.5
 Skap2
src family associated phosphoprotein 2
chr3_+_68572245 1.965 ENSMUST00000170788.2
 Schip1
schwannomin interacting protein 1
chr10_+_81628702 1.951 ENSMUST00000129622.1
 Ankrd24
ankyrin repeat domain 24
chr18_+_4994600 1.913 ENSMUST00000140448.1
 Svil
supervillin
chr5_+_27261916 1.900 ENSMUST00000101471.3
 Dpp6
dipeptidylpeptidase 6
chr3_-_110143937 1.871 ENSMUST00000051253.3
 Ntng1
netrin G1
chr12_+_53248677 1.757 ENSMUST00000101432.2
 Npas3
neuronal PAS domain protein 3
chr13_+_72628802 1.662 ENSMUST00000074372.4
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr2_-_152951688 1.488 ENSMUST00000109811.3
 Dusp15
dual specificity phosphatase-like 15
chr3_+_98013503 1.435 ENSMUST00000079812.6
 Notch2
notch 2
chr17_+_70522083 1.422 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chrX_+_110814390 1.391 ENSMUST00000078229.3
 Pou3f4
POU domain, class 3, transcription factor 4
chr13_+_31806627 1.373 ENSMUST00000062292.2
 Foxc1
forkhead box C1
chr9_-_21312255 1.325 ENSMUST00000115433.3
ENSMUST00000003397.7
 Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr17_+_70522149 1.304 ENSMUST00000140728.1
 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr14_-_69503316 1.282 ENSMUST00000179116.2
 Gm21464
predicted gene, 21464
chr11_-_20332654 1.256 ENSMUST00000004634.6
 Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr17_-_25081138 1.245 ENSMUST00000024984.6
 Tmem204
transmembrane protein 204
chr6_-_21851914 1.225 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
 Tspan12


tetraspanin 12


chr6_-_136875794 1.099 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr14_+_56575603 1.095 ENSMUST00000161553.1
 Parp4
poly (ADP-ribose) polymerase family, member 4
chr1_+_153665274 0.931 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr2_+_158375638 0.873 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr9_-_4796218 0.792 ENSMUST00000027020.6
ENSMUST00000063508.7
ENSMUST00000163309.1
 Gria4


glutamate receptor, ionotropic, AMPA4 (alpha 4)


chr11_+_103774150 0.789 ENSMUST00000000127.5
 Wnt3
wingless-related MMTV integration site 3
chr12_-_80260356 0.744 ENSMUST00000021554.8
 Actn1
actinin, alpha 1
chr2_-_26246707 0.734 ENSMUST00000166349.1
 C030048H21Rik
RIKEN cDNA C030048H21 gene
chr10_+_75037291 0.731 ENSMUST00000139384.1
 Rab36
RAB36, member RAS oncogene family
chr13_+_72628831 0.692 ENSMUST00000169028.1
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr1_+_10993452 0.677 ENSMUST00000027056.5
 Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr15_+_98167806 0.671 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr14_-_69284982 0.639 ENSMUST00000183882.1
ENSMUST00000037064.4
 Slc25a37

solute carrier family 25, member 37

chr7_+_144838590 0.628 ENSMUST00000105898.1
 Fgf3
fibroblast growth factor 3
chr15_-_53346118 0.597 ENSMUST00000077273.2
 Ext1
exostoses (multiple) 1
chr19_-_41743665 0.551 ENSMUST00000025993.3
 Slit1
slit homolog 1 (Drosophila)
chr10_+_14523062 0.547 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr16_-_18876522 0.503 ENSMUST00000119273.1
 Mrpl40
mitochondrial ribosomal protein L40
chr10_+_26078255 0.490 ENSMUST00000041011.3
 Gm9767
predicted gene 9767
chr4_-_108406676 0.474 ENSMUST00000184609.1
 Gpx7
glutathione peroxidase 7
chr4_-_35845204 0.471 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr8_+_95825353 0.470 ENSMUST00000074053.4
 Gm10094
predicted gene 10094
chr17_+_55445375 0.468 ENSMUST00000133899.1
ENSMUST00000086878.3
 St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr18_-_56562215 0.458 ENSMUST00000170309.1
 Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr18_-_56562261 0.446 ENSMUST00000066208.6
ENSMUST00000172734.1
 Aldh7a1

aldehyde dehydrogenase family 7, member A1

chr18_-_56562187 0.432 ENSMUST00000171844.2
 Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr5_-_137684665 0.419 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
 Agfg2


ArfGAP with FG repeats 2


chr1_-_45503282 0.414 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr9_+_65890237 0.405 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr6_-_88446491 0.375 ENSMUST00000165242.1
 Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr3_-_88762244 0.367 ENSMUST00000183267.1
 Syt11
synaptotagmin XI
chr16_+_18877037 0.324 ENSMUST00000120532.1
ENSMUST00000004222.7
 Hira

histone cell cycle regulation defective homolog A (S. cerevisiae)

chr10_-_63421739 0.316 ENSMUST00000054760.4
 Gm7075
predicted gene 7075
chr18_+_56562443 0.309 ENSMUST00000130163.1
ENSMUST00000132628.1
 Phax

phosphorylated adaptor for RNA export

chr17_-_28622419 0.306 ENSMUST00000114767.1
 Srpk1
serine/arginine-rich protein specific kinase 1
chr5_+_137030275 0.301 ENSMUST00000041543.8
 Vgf
VGF nerve growth factor inducible
chr1_+_89454769 0.294 ENSMUST00000027521.8
ENSMUST00000074945.5
 Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr16_-_18876655 0.287 ENSMUST00000023391.8
 Mrpl40
mitochondrial ribosomal protein L40
chrX_-_150812932 0.214 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
 Maged2


melanoma antigen, family D, 2


chr8_-_67515606 0.207 ENSMUST00000032981.5
 Gm9755
predicted pseudogene 9755
chr3_-_58525867 0.201 ENSMUST00000029385.7
 Serp1
stress-associated endoplasmic reticulum protein 1
chr5_+_42067960 0.178 ENSMUST00000087332.4
 Gm16223
predicted gene 16223
chr9_+_110344185 0.170 ENSMUST00000142100.1
 Scap
SREBF chaperone
chr11_-_116189542 0.140 ENSMUST00000148601.1
 Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr2_+_36230426 0.100 ENSMUST00000062069.5
 Ptgs1
prostaglandin-endoperoxide synthase 1
chr10_-_78352469 0.089 ENSMUST00000138035.1
 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr7_+_119690026 0.089 ENSMUST00000047045.8
 Acsm4
acyl-CoA synthetase medium-chain family member 4
chr2_+_112261926 0.071 ENSMUST00000028553.3
 Nop10
NOP10 ribonucleoprotein
chr3_+_58525821 0.062 ENSMUST00000029387.8
 Eif2a
eukaryotic translation initiation factor 2A
chrX_-_134161928 0.059 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr7_-_30534180 0.054 ENSMUST00000044338.4
 Arhgap33
Rho GTPase activating protein 33
chr5_-_135573036 0.054 ENSMUST00000004936.6
 Ccl24
chemokine (C-C motif) ligand 24
chr5_-_143732273 0.052 ENSMUST00000053287.5
 Usp42
ubiquitin specific peptidase 42
chr7_-_127708886 0.047 ENSMUST00000061468.8
 Bcl7c
B cell CLL/lymphoma 7C
chr11_-_40755201 0.036 ENSMUST00000020576.7
 Ccng1
cyclin G1
chr9_+_113930934 0.018 ENSMUST00000084885.5
ENSMUST00000009885.7
 Ubp1

upstream binding protein 1

chr9_+_58129476 0.002 ENSMUST00000133287.1
 Stra6
stimulated by retinoic acid gene 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
1.6 16.4 GO:0010572 positive regulation of platelet activation(GO:0010572)
1.1 3.2 GO:0051695 actin filament uncapping(GO:0051695)
0.6 5.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.5 6.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.5 3.5 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.5 1.4 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.5 1.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.3 3.4 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 3.0 GO:0042473 outer ear morphogenesis(GO:0042473)
0.3 0.8 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 3.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.2 2.7 GO:0070842 aggresome assembly(GO:0070842)
0.2 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 1.3 GO:0015808 L-alanine transport(GO:0015808)
0.2 1.4 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 1.8 GO:0042711 maternal behavior(GO:0042711)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 2.0 GO:0001553 luteinization(GO:0001553)
0.1 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.3 GO:0051030 snRNA transport(GO:0051030)
0.1 0.6 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 0.9 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 1.9 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 0.3 GO:0043084 penile erection(GO:0043084)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 1.2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.4 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0035633 negative regulation of norepinephrine secretion(GO:0010700) maintenance of blood-brain barrier(GO:0035633)
0.0 0.1 GO:2000416 regulation of eosinophil migration(GO:2000416) positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 1.1 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 2.3 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 1.1 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 3.4 GO:0006631 fatty acid metabolic process(GO:0006631)
0.0 2.1 GO:0002757 immune response-activating signal transduction(GO:0002757)
0.0 0.3 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 0.7 GO:0032127 dense core granule membrane(GO:0032127)
0.2 18.4 GO:0030175 filopodium(GO:0030175)
0.2 4.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.9 GO:0043034 costamere(GO:0043034)
0.0 3.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.4 GO:0043204 perikaryon(GO:0043204)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 6.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0004962 endothelin receptor activity(GO:0004962)
1.5 16.4 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.5 5.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.4 3.2 GO:0031432 thyroid hormone receptor coactivator activity(GO:0030375) titin binding(GO:0031432)
0.4 2.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 1.3 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 3.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 3.3 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.2 1.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 1.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:0004096 catalase activity(GO:0004096)
0.1 1.4 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.8 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 3.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 5.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)