Motif ID: Hoxa10

Z-value: 0.849


Transcription factors associated with Hoxa10:

Gene SymbolEntrez IDGene Name
Hoxa10 ENSMUSG00000000938.11 Hoxa10



Activity profile for motif Hoxa10.

activity profile for motif Hoxa10


Sorted Z-values histogram for motif Hoxa10

Sorted Z-values for motif Hoxa10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa10

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_106935720 5.927 ENSMUST00000047425.3
Sntb2
syntrophin, basic 2
chr8_-_33747724 5.686 ENSMUST00000179364.1
Smim18
small integral membrane protein 18
chr6_-_56901870 5.468 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr11_-_42000284 5.445 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr17_-_81649607 5.102 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr9_-_112232449 4.955 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr1_+_66321708 4.828 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chrX_-_43274786 4.802 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chr5_-_131616599 4.758 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr3_-_123672321 4.742 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr2_-_79908428 4.521 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr3_+_102010138 4.462 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr8_+_12984246 4.363 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr18_+_37518341 4.331 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr18_+_37513652 4.305 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr19_+_4711153 4.259 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr2_+_68117713 4.193 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr5_-_103100054 4.096 ENSMUST00000112848.1
Mapk10
mitogen-activated protein kinase 10
chr9_+_53771499 3.923 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr2_+_4300462 3.733 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr4_+_43406435 3.702 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr13_-_99516537 3.566 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr2_-_37647199 3.548 ENSMUST00000028279.3
Strbp
spermatid perinuclear RNA binding protein
chr18_-_89769479 3.422 ENSMUST00000097495.3
Dok6
docking protein 6
chr9_-_50739365 3.396 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr19_+_43440404 3.388 ENSMUST00000165311.1
Cnnm1
cyclin M1
chrX_+_56609843 3.220 ENSMUST00000077741.5
ENSMUST00000114784.2
Slc9a6

solute carrier family 9 (sodium/hydrogen exchanger), member 6

chr13_+_109926832 3.140 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr2_-_79908389 3.095 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr8_+_58912257 3.093 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr5_-_118244861 3.040 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr11_-_69822144 2.919 ENSMUST00000045771.6
Spem1
sperm maturation 1
chr11_-_78984831 2.896 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chr10_-_29144194 2.793 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr3_+_26331150 2.702 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr5_-_123666682 2.625 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr18_+_37496997 2.596 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr8_-_54718664 2.567 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr18_+_37411674 2.554 ENSMUST00000051126.2
Pcdhb10
protocadherin beta 10
chr11_-_78984946 2.511 ENSMUST00000108268.3
Lgals9
lectin, galactose binding, soluble 9
chr4_-_91376433 2.510 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr17_-_6079693 2.507 ENSMUST00000024570.5
ENSMUST00000097432.3
Serac1

serine active site containing 1

chr6_+_34354119 2.502 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr13_-_74376566 2.481 ENSMUST00000091481.2
Zfp72
zinc finger protein 72
chr6_+_54264839 2.478 ENSMUST00000146114.1
Chn2
chimerin (chimaerin) 2
chr3_+_67892189 2.461 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chrX_+_112604274 2.299 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr13_+_18717289 2.261 ENSMUST00000072961.4
Vps41
vacuolar protein sorting 41 (yeast)
chr10_-_11082287 2.225 ENSMUST00000105561.2
ENSMUST00000044306.6
Grm1

glutamate receptor, metabotropic 1

chr7_-_29125142 2.203 ENSMUST00000179893.1
ENSMUST00000032813.9
Ryr1

ryanodine receptor 1, skeletal muscle

chr3_+_136670076 2.135 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr1_-_140183404 2.099 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr1_-_140183283 2.041 ENSMUST00000111977.1
Cfh
complement component factor h
chr8_+_83666827 1.938 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr11_+_44617310 1.915 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr7_-_25882407 1.911 ENSMUST00000163316.2
Gm6434
predicted gene 6434
chrX_+_112615301 1.862 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr13_-_92030897 1.862 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr4_-_109202217 1.854 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
Osbpl9


oxysterol binding protein-like 9


chr2_-_73625731 1.806 ENSMUST00000070579.6
Chn1
chimerin (chimaerin) 1
chr1_-_156939626 1.793 ENSMUST00000063199.6
ENSMUST00000027886.7
ENSMUST00000172057.1
Ralgps2


Ral GEF with PH domain and SH3 binding motif 2


chr17_+_29093763 1.757 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr9_+_54538984 1.733 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr18_+_33464163 1.664 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr10_+_29143996 1.577 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr9_+_58582397 1.576 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr8_-_41054771 1.414 ENSMUST00000093534.4
Mtus1
mitochondrial tumor suppressor 1
chr18_-_23038656 1.402 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr17_+_6079786 1.387 ENSMUST00000039487.3
Gtf2h5
general transcription factor IIH, polypeptide 5
chr13_+_24614608 1.379 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr2_-_34755229 1.376 ENSMUST00000102800.1
Gapvd1
GTPase activating protein and VPS9 domains 1
chr13_-_18031616 1.375 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr10_-_29362012 1.365 ENSMUST00000161508.1
Rnf146
ring finger protein 146
chr9_-_46319984 1.319 ENSMUST00000159565.1
4931429L15Rik
RIKEN cDNA 4931429L15 gene
chrM_+_14138 1.254 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr11_+_87109221 1.249 ENSMUST00000020794.5
Ska2
spindle and kinetochore associated complex subunit 2
chr1_+_179961110 1.234 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr1_+_127729405 1.234 ENSMUST00000038006.6
Acmsd
amino carboxymuconate semialdehyde decarboxylase
chr2_-_114201416 1.212 ENSMUST00000050668.3
Zfp770
zinc finger protein 770
chrX_-_136741155 1.164 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr19_+_11965817 1.120 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr13_-_41847482 1.117 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr5_+_121777929 1.106 ENSMUST00000160821.1
Atxn2
ataxin 2
chr6_-_122856151 1.096 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr17_+_6079928 1.066 ENSMUST00000100955.2
Gtf2h5
general transcription factor IIH, polypeptide 5
chr4_+_42629719 1.054 ENSMUST00000166898.2
Gm2564
predicted gene 2564
chr4_+_100776664 1.042 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr6_-_99044414 1.042 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr6_-_99028874 1.034 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr6_+_127453667 1.006 ENSMUST00000112193.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr12_+_55089202 0.975 ENSMUST00000021407.10
Srp54a
signal recognition particle 54A
chr1_+_58210397 0.962 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr8_+_110618577 0.938 ENSMUST00000034190.9
Vac14
Vac14 homolog (S. cerevisiae)
chr3_-_94436574 0.923 ENSMUST00000029787.4
Oaz3
ornithine decarboxylase antizyme 3
chr10_+_97565436 0.923 ENSMUST00000038160.4
Lum
lumican
chr2_-_34826187 0.907 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2


F-box and WD-40 domain protein 2


chr8_-_105565985 0.870 ENSMUST00000013304.7
Atp6v0d1
ATPase, H+ transporting, lysosomal V0 subunit D1
chr17_-_33760451 0.846 ENSMUST00000057373.7
Rab11b
RAB11B, member RAS oncogene family
chr3_-_59262825 0.829 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr7_+_29238434 0.810 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr12_+_10390756 0.803 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr11_+_3330401 0.799 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr11_-_107348130 0.792 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_138326234 0.772 ENSMUST00000105817.3
ENSMUST00000030536.6
Pink1

PTEN induced putative kinase 1

chr5_+_121749196 0.771 ENSMUST00000161064.1
Atxn2
ataxin 2
chr11_-_83645621 0.770 ENSMUST00000182502.1
Rpl9-ps1
ribosomal protein L9, pseudogene 1
chr7_-_126160992 0.765 ENSMUST00000164741.1
Xpo6
exportin 6
chr12_+_55239326 0.759 ENSMUST00000164243.1
Srp54c
signal recognition particle 54C
chr11_-_110168073 0.758 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr2_-_77519565 0.740 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chrM_+_3906 0.726 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr19_-_45591820 0.719 ENSMUST00000160003.1
ENSMUST00000162879.1
Fbxw4

F-box and WD-40 domain protein 4

chr8_+_46492789 0.718 ENSMUST00000110371.1
Acsl1
acyl-CoA synthetase long-chain family member 1
chr16_-_35871544 0.699 ENSMUST00000042665.8
Parp14
poly (ADP-ribose) polymerase family, member 14
chr1_+_179960472 0.697 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr2_+_164823001 0.693 ENSMUST00000132282.1
Zswim1
zinc finger SWIM-type containing 1
chr1_+_153874335 0.692 ENSMUST00000055314.3
Gm5531
predicted gene 5531
chr8_+_93810832 0.672 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr6_+_6955993 0.672 ENSMUST00000040826.5
Acn9
ACN9 homolog (S. cerevisiae)
chr4_-_119383732 0.613 ENSMUST00000044781.2
ENSMUST00000084307.3
Ccdc30

coiled-coil domain containing 30

chr18_-_3281712 0.601 ENSMUST00000182204.1
ENSMUST00000154705.1
ENSMUST00000182833.1
ENSMUST00000151084.1
Crem



cAMP responsive element modulator



chr8_+_85432686 0.592 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr10_-_111997204 0.590 ENSMUST00000074805.5
Glipr1
GLI pathogenesis-related 1 (glioma)
chr10_+_5593718 0.589 ENSMUST00000051809.8
Myct1
myc target 1
chr2_-_34826071 0.584 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr16_+_48872608 0.513 ENSMUST00000065666.4
Retnlg
resistin like gamma
chr12_+_84361968 0.487 ENSMUST00000021661.6
Coq6
coenzyme Q6 homolog (yeast)
chr18_-_12860197 0.486 ENSMUST00000124570.1
Osbpl1a
oxysterol binding protein-like 1A
chr5_+_121802230 0.470 ENSMUST00000162995.1
Atxn2
ataxin 2
chr17_+_33824591 0.443 ENSMUST00000048249.6
Ndufa7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)
chr2_+_69790968 0.443 ENSMUST00000180290.1
Phospho2
phosphatase, orphan 2
chr9_+_55326913 0.442 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078

expressed sequence AI118078

chr7_+_29238323 0.435 ENSMUST00000108238.1
ENSMUST00000032809.3
ENSMUST00000138128.1
Yif1b


Yip1 interacting factor homolog B (S. cerevisiae)


chr7_-_73537621 0.413 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr4_-_11981265 0.393 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chr2_-_149798701 0.389 ENSMUST00000148202.1
ENSMUST00000139471.1
Gm14133

predicted gene 14133

chr2_+_15049395 0.383 ENSMUST00000017562.6
Arl5b
ADP-ribosylation factor-like 5B
chr1_+_59684949 0.341 ENSMUST00000027174.3
Nop58
NOP58 ribonucleoprotein
chr10_-_116549101 0.327 ENSMUST00000164088.1
Cnot2
CCR4-NOT transcription complex, subunit 2
chr3_+_60877002 0.242 ENSMUST00000099086.2
Gm8325
predicted pseudogene 8325
chr18_-_34651703 0.242 ENSMUST00000025228.5
ENSMUST00000133181.1
Cdc23

CDC23 cell division cycle 23

chr2_+_83812567 0.231 ENSMUST00000051454.3
Fam171b
family with sequence similarity 171, member B
chr1_+_74713551 0.199 ENSMUST00000027356.5
Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
chr2_+_36230426 0.190 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr1_+_193173469 0.185 ENSMUST00000161235.1
ENSMUST00000110831.2
ENSMUST00000178744.1
A130010J15Rik


RIKEN cDNA A130010J15 gene


chr6_-_3494587 0.180 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr18_-_43477764 0.162 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr7_-_144470714 0.131 ENSMUST00000033407.6
Cttn
cortactin
chr6_+_59208870 0.102 ENSMUST00000062626.3
Tigd2
tigger transposable element derived 2
chr15_+_85510812 0.098 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr9_+_122888471 0.081 ENSMUST00000063980.6
Zkscan7
zinc finger with KRAB and SCAN domains 7
chr1_+_182124737 0.076 ENSMUST00000111018.1
ENSMUST00000027792.5
Srp9

signal recognition particle 9

chr5_+_100196611 0.072 ENSMUST00000066813.1
Gm9932
predicted gene 9932
chr13_+_58281183 0.035 ENSMUST00000180882.1
ENSMUST00000180452.1
Gm26555

predicted gene, 26555

chr1_+_155158703 0.029 ENSMUST00000027743.7
Stx6
syntaxin 6
chr19_+_24875679 0.024 ENSMUST00000073080.5
Gm10053
predicted gene 10053

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:2000562 negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.6 4.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.2 7.3 GO:0071415 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.8 2.5 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.7 2.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.7 4.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 4.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 2.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.6 5.4 GO:0071420 cellular response to histamine(GO:0071420)
0.5 5.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.5 1.0 GO:0046110 xanthine metabolic process(GO:0046110)
0.5 3.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.5 2.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.4 7.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 1.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.4 1.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.4 1.8 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.4 2.5 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.3 1.6 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.3 4.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 0.8 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.3 2.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.3 3.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 2.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 0.8 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.3 1.3 GO:0033762 response to glucagon(GO:0033762)
0.2 3.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 6.6 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.2 0.9 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 0.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 2.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2 0.8 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 3.6 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.2 4.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 1.8 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.2 4.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2 0.5 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 4.5 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 3.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 5.0 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 3.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 1.9 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 1.9 GO:0007097 nuclear migration(GO:0007097)
0.1 1.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.8 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.7 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 1.1 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.1 0.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 2.9 GO:0030317 sperm motility(GO:0030317)
0.1 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.4 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 4.8 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 1.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.9 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.9 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 1.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 1.4 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 5.9 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.4 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 3.9 GO:0006869 lipid transport(GO:0006869)
0.0 0.6 GO:0051591 response to cAMP(GO:0051591)
0.0 1.8 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.7 GO:0010506 regulation of autophagy(GO:0010506)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.3 GO:0008091 spectrin(GO:0008091)
0.6 1.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.5 3.2 GO:0044308 axonal spine(GO:0044308)
0.5 4.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 2.2 GO:0030314 junctional membrane complex(GO:0030314)
0.4 2.1 GO:0005955 calcineurin complex(GO:0005955)
0.3 2.3 GO:0033263 CORVET complex(GO:0033263)
0.3 2.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.3 5.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.3 2.5 GO:0000439 core TFIIH complex(GO:0000439)
0.3 2.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 3.6 GO:0043196 varicosity(GO:0043196)
0.2 1.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.2 0.9 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 4.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 3.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 5.1 GO:0030315 T-tubule(GO:0030315)
0.1 5.1 GO:0072562 blood microparticle(GO:0072562)
0.0 1.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.9 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 4.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 3.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 3.4 GO:0043679 axon terminus(GO:0043679)
0.0 1.9 GO:0005768 endosome(GO:0005768)
0.0 1.9 GO:0042641 actomyosin(GO:0042641)
0.0 4.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 7.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 5.9 GO:0005874 microtubule(GO:0005874)
0.0 2.5 GO:0045202 synapse(GO:0045202)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0001851 complement component C3b binding(GO:0001851)
1.3 5.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
1.1 7.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.0 8.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.9 5.4 GO:0016936 galactoside binding(GO:0016936)
0.9 1.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.7 2.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.7 4.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.6 2.2 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)
0.5 4.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.5 1.9 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.4 2.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.4 3.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 1.1 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.4 2.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 5.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 5.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 2.5 GO:0000182 rDNA binding(GO:0000182)
0.3 0.8 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 4.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.2 0.7 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.2 2.3 GO:0050692 DBD domain binding(GO:0050692)
0.2 0.9 GO:0071532 ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532)
0.2 4.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 2.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.4 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.1 1.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.7 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 3.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 3.1 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 3.4 GO:0005158 insulin receptor binding(GO:0005158)
0.1 4.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 12.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.5 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0 3.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 2.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 1.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.8 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 3.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 2.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 4.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)