Motif ID: Hoxa10

Z-value: 0.849


Transcription factors associated with Hoxa10:

Gene SymbolEntrez IDGene Name
Hoxa10 ENSMUSG00000000938.11 Hoxa10



Activity profile for motif Hoxa10.

activity profile for motif Hoxa10


Sorted Z-values histogram for motif Hoxa10

Sorted Z-values for motif Hoxa10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa10

PNG image of the network

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Top targets:


Showing 1 to 20 of 156 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_106935720 5.927 ENSMUST00000047425.3
Sntb2
syntrophin, basic 2
chr8_-_33747724 5.686 ENSMUST00000179364.1
Smim18
small integral membrane protein 18
chr6_-_56901870 5.468 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr11_-_42000284 5.445 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr17_-_81649607 5.102 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr9_-_112232449 4.955 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr1_+_66321708 4.828 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chrX_-_43274786 4.802 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chr5_-_131616599 4.758 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr3_-_123672321 4.742 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr2_-_79908428 4.521 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr3_+_102010138 4.462 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr8_+_12984246 4.363 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr18_+_37518341 4.331 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr18_+_37513652 4.305 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr19_+_4711153 4.259 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr2_+_68117713 4.193 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr5_-_103100054 4.096 ENSMUST00000112848.1
Mapk10
mitogen-activated protein kinase 10
chr9_+_53771499 3.923 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr2_+_4300462 3.733 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.6 GO:0046069 cGMP catabolic process(GO:0046069)
1.2 7.3 GO:0071415 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.2 6.6 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 5.9 GO:0043087 regulation of GTPase activity(GO:0043087)
0.5 5.5 GO:0046085 adenosine metabolic process(GO:0046085)
1.8 5.4 GO:2000562 negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.6 5.4 GO:0071420 cellular response to histamine(GO:0071420)
0.1 5.0 GO:0034605 cellular response to heat(GO:0034605)
1.6 4.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 4.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 4.8 GO:0030010 establishment of cell polarity(GO:0030010)
0.1 4.5 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.2 4.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.3 4.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.7 4.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 4.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 3.9 GO:0006869 lipid transport(GO:0006869)
0.1 3.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 3.6 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 3.5 GO:0007638 mechanosensory behavior(GO:0007638)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 5.9 GO:0005874 microtubule(GO:0005874)
0.3 5.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 5.1 GO:0030315 T-tubule(GO:0030315)
0.1 5.1 GO:0072562 blood microparticle(GO:0072562)
0.5 4.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 4.6 GO:0000139 Golgi membrane(GO:0000139)
0.7 4.3 GO:0008091 spectrin(GO:0008091)
0.1 4.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 4.1 GO:0043204 perikaryon(GO:0043204)
0.0 3.7 GO:0005923 bicellular tight junction(GO:0005923)
0.2 3.6 GO:0043196 varicosity(GO:0043196)
0.0 3.4 GO:0043679 axon terminus(GO:0043679)
0.5 3.2 GO:0044308 axonal spine(GO:0044308)
0.1 3.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 2.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 2.5 GO:0000439 core TFIIH complex(GO:0000439)
0.0 2.5 GO:0045202 synapse(GO:0045202)
0.3 2.3 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.7 GO:0005516 calmodulin binding(GO:0005516)
1.0 8.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.1 7.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 5.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.9 5.4 GO:0016936 galactoside binding(GO:0016936)
0.3 5.4 GO:0004890 GABA-A receptor activity(GO:0004890)
1.3 5.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 4.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.7 4.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 4.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 4.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.5 4.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
1.4 4.1 GO:0001851 complement component C3b binding(GO:0001851)
0.2 4.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 3.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 3.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 3.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 3.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.4 3.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)