Motif ID: Hoxa11_Hoxc12

Z-value: 1.114

Transcription factors associated with Hoxa11_Hoxc12:

Gene SymbolEntrez IDGene Name
Hoxa11 ENSMUSG00000038210.9 Hoxa11
Hoxc12 ENSMUSG00000050328.2 Hoxc12






Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa11_Hoxc12

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_35076902 22.544 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr1_-_56978534 18.686 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr2_+_28205648 12.947 ENSMUST00000102879.3
ENSMUST00000028177.4
Olfm1

olfactomedin 1

chr14_+_80000292 10.115 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr6_+_108213086 10.062 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr13_+_16014457 9.891 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr6_-_55681257 9.589 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr16_-_45408955 8.421 ENSMUST00000163230.1
Cd200
CD200 antigen
chr16_-_57231434 7.739 ENSMUST00000023431.6
Tbc1d23
TBC1 domain family, member 23
chr14_+_27622433 7.732 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr17_+_8283762 7.122 ENSMUST00000155364.1
ENSMUST00000046754.8
ENSMUST00000124023.1
Mpc1


mitochondrial pyruvate carrier 1


chr15_-_43869993 6.666 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr17_+_6270475 6.577 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr9_-_55919605 6.114 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chrX_+_73064787 5.940 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr1_+_178529113 5.650 ENSMUST00000161017.1
Kif26b
kinesin family member 26B
chr18_-_43393346 5.590 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr11_-_115628125 5.429 ENSMUST00000155709.1
ENSMUST00000021089.4
Slc25a19

solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19

chr11_-_115627948 5.312 ENSMUST00000154623.1
ENSMUST00000106503.3
ENSMUST00000141614.1
Slc25a19


solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19


chr16_-_74411776 5.234 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr5_+_66968961 5.132 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr11_-_115628260 4.987 ENSMUST00000178003.1
Slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr17_-_6477102 4.960 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr1_+_43730593 4.831 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr13_-_54749849 4.830 ENSMUST00000135343.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr7_+_4460687 4.747 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chr18_+_69346143 4.583 ENSMUST00000114980.1
Tcf4
transcription factor 4
chr3_-_117360876 4.571 ENSMUST00000061071.8
D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr9_+_53771499 4.357 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr6_+_96115249 4.217 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr11_-_62457772 3.974 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr8_+_40307458 3.887 ENSMUST00000068999.7
Micu3
mitochondrial calcium uptake family, member 3
chrX_+_41401304 3.692 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr4_+_102741287 3.487 ENSMUST00000097948.2
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr2_+_23068168 3.315 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
Acbd5


acyl-Coenzyme A binding domain containing 5


chrX_+_41401128 3.125 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr3_+_32436376 3.117 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr15_-_101850778 3.077 ENSMUST00000023790.3
Krt1
keratin 1
chr6_-_118455475 3.049 ENSMUST00000161519.1
ENSMUST00000069292.7
Zfp248

zinc finger protein 248

chr13_+_109685994 2.930 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr11_+_77216180 2.798 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2

slingshot homolog 2 (Drosophila)

chr8_-_69625503 2.787 ENSMUST00000121886.1
Zfp868
zinc finger protein 868
chr6_+_91878034 2.696 ENSMUST00000037783.5
Ccdc174
coiled-coil domain containing 174
chr4_-_129378116 2.640 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chrX_-_165004829 2.632 ENSMUST00000114890.2
Gm17604
predicted gene, 17604
chr16_-_16600533 2.482 ENSMUST00000159542.1
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr18_+_37333853 2.459 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr13_+_98263242 2.357 ENSMUST00000022164.8
ENSMUST00000150352.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr3_+_129532386 2.318 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr13_+_98263187 2.288 ENSMUST00000091356.3
ENSMUST00000123924.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr1_-_189922338 2.270 ENSMUST00000027897.7
Smyd2
SET and MYND domain containing 2
chr7_-_73537621 2.227 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr7_-_141435327 2.190 ENSMUST00000138865.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr18_+_37655891 2.171 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr13_+_98263105 2.170 ENSMUST00000150916.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr5_-_20951769 2.153 ENSMUST00000036489.5
Rsbn1l
round spermatid basic protein 1-like
chr2_-_104712122 2.067 ENSMUST00000111118.1
ENSMUST00000028597.3
Tcp11l1

t-complex 11 like 1

chr8_+_25720054 2.036 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr2_-_120970706 1.984 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr2_-_180824596 1.958 ENSMUST00000148700.1
Gm14340
predicted gene 14340
chr16_+_23224724 1.847 ENSMUST00000023601.7
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr11_-_95309557 1.843 ENSMUST00000092766.5
ENSMUST00000072621.5
Kat7

K(lysine) acetyltransferase 7

chr12_+_78226627 1.833 ENSMUST00000110388.2
ENSMUST00000052472.4
Gphn

gephyrin

chr19_+_4097392 1.822 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chr5_-_73256555 1.817 ENSMUST00000101127.5
ENSMUST00000171179.1
Fryl
Fryl
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chrX_+_20364481 1.767 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
Rp2h


retinitis pigmentosa 2 homolog (human)


chr1_-_93101825 1.754 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr10_+_90071095 1.737 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr17_+_22361453 1.716 ENSMUST00000149699.1
ENSMUST00000088765.2
ENSMUST00000072477.4
ENSMUST00000121315.1
Zfp758



zinc finger protein 758



chr9_-_44407526 1.661 ENSMUST00000034623.6
Trappc4
trafficking protein particle complex 4
chr7_-_141434532 1.601 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr17_-_13761441 1.595 ENSMUST00000127032.1
Tcte2
t-complex-associated testis expressed 2
chr13_-_12464925 1.590 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr11_-_23895208 1.535 ENSMUST00000102863.2
ENSMUST00000020513.3
Papolg

poly(A) polymerase gamma

chr5_-_123666682 1.444 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr16_+_75592844 1.426 ENSMUST00000114249.1
ENSMUST00000046378.7
ENSMUST00000114253.1
Rbm11


RNA binding motif protein 11


chr17_-_24455265 1.406 ENSMUST00000056032.7
E4f1
E4F transcription factor 1
chr6_-_29216301 1.390 ENSMUST00000162739.1
ENSMUST00000162099.1
ENSMUST00000159124.1
Impdh1


inosine 5'-phosphate dehydrogenase 1


chr3_+_88621102 1.376 ENSMUST00000029694.7
ENSMUST00000176804.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr11_-_62789445 1.360 ENSMUST00000054654.6
Zfp286
zinc finger protein 286
chr7_-_142661858 1.342 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr3_-_88458876 1.333 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr6_-_29216277 1.248 ENSMUST00000162215.1
Impdh1
inosine 5'-phosphate dehydrogenase 1
chr1_+_182409162 1.244 ENSMUST00000117245.1
Trp53bp2
transformation related protein 53 binding protein 2
chr13_-_99344652 1.231 ENSMUST00000022153.6
Ptcd2
pentatricopeptide repeat domain 2
chr13_-_66851513 1.225 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr8_+_104250925 1.209 ENSMUST00000098464.4
Cklf
chemokine-like factor
chr11_-_62789402 1.175 ENSMUST00000108705.1
Zfp286
zinc finger protein 286
chr4_-_45408646 1.138 ENSMUST00000153904.1
ENSMUST00000132815.2
ENSMUST00000107796.1
ENSMUST00000116341.3
Slc25a51



solute carrier family 25, member 51



chr12_-_23780265 1.118 ENSMUST00000072014.4
Gm10330
predicted gene 10330
chr12_-_27160311 1.113 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr10_-_120979327 1.092 ENSMUST00000119944.1
ENSMUST00000119093.1
Lemd3

LEM domain containing 3

chr12_+_59066908 1.050 ENSMUST00000021381.4
Pnn
pinin
chr3_-_88459047 1.036 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr11_-_30986326 0.991 ENSMUST00000020553.4
ENSMUST00000101394.4
Chac2

ChaC, cation transport regulator 2

chr8_+_105225145 0.970 ENSMUST00000034361.3
D230025D16Rik
RIKEN cDNA D230025D16 gene
chr4_+_108328136 0.965 ENSMUST00000131656.1
Selrc1
Sel1 repeat containing 1
chr11_+_82045705 0.958 ENSMUST00000021011.2
Ccl7
chemokine (C-C motif) ligand 7
chr19_-_46338632 0.927 ENSMUST00000051234.8
ENSMUST00000167861.1
Cuedc2

CUE domain containing 2

chr11_-_5542177 0.926 ENSMUST00000020776.4
Ccdc117
coiled-coil domain containing 117
chr8_+_31150307 0.897 ENSMUST00000098842.2
Tti2
TELO2 interacting protein 2
chr6_-_87809757 0.893 ENSMUST00000032134.7
Rab43
RAB43, member RAS oncogene family
chr6_+_42286709 0.889 ENSMUST00000163936.1
Clcn1
chloride channel 1
chr3_+_89177463 0.859 ENSMUST00000029684.8
ENSMUST00000120697.1
ENSMUST00000098941.4
Scamp3


secretory carrier membrane protein 3


chr14_-_104522615 0.795 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr11_+_55213783 0.725 ENSMUST00000108867.1
Slc36a1
solute carrier family 36 (proton/amino acid symporter), member 1
chr7_+_126649297 0.703 ENSMUST00000032956.8
Ccdc101
coiled-coil domain containing 101
chr9_-_50659780 0.691 ENSMUST00000034567.3
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr12_-_20900867 0.687 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr6_+_42286676 0.639 ENSMUST00000031894.6
Clcn1
chloride channel 1
chr9_+_3404058 0.576 ENSMUST00000027027.5
Cwf19l2
CWF19-like 2, cell cycle control (S. pombe)
chr13_-_66852017 0.564 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr4_+_130913264 0.498 ENSMUST00000156225.1
ENSMUST00000156742.1
Laptm5

lysosomal-associated protein transmembrane 5

chr7_-_126649556 0.496 ENSMUST00000084587.1
2510046G10Rik
RIKEN cDNA 2510046G10 gene
chr4_+_130913120 0.406 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr16_-_23225334 0.399 ENSMUST00000055369.4
BC106179
cDNA sequence BC106179
chr19_+_5406815 0.375 ENSMUST00000174412.1
ENSMUST00000153017.2
4930481A15Rik

RIKEN cDNA 4930481A15 gene

chr7_-_46795881 0.327 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr19_-_7483212 0.289 ENSMUST00000088169.5
Rtn3
reticulon 3
chr8_-_69373914 0.279 ENSMUST00000095282.1
Gm10311
predicted gene 10311
chr6_+_40325471 0.237 ENSMUST00000031977.8
Agk
acylglycerol kinase
chr13_+_58281183 0.231 ENSMUST00000180882.1
ENSMUST00000180452.1
Gm26555

predicted gene, 26555

chr14_+_49172202 0.209 ENSMUST00000153488.1
Naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr19_-_4012656 0.160 ENSMUST00000134479.1
ENSMUST00000128787.1
ENSMUST00000133474.1
ENSMUST00000136921.1
ENSMUST00000042497.7
Ndufv1




NADH dehydrogenase (ubiquinone) flavoprotein 1




chr16_+_87354185 0.116 ENSMUST00000054442.4
ENSMUST00000118310.1
ENSMUST00000120284.1
ENSMUST00000118115.1
N6amt1



N-6 adenine-specific DNA methyltransferase 1 (putative)



chr11_-_97699634 0.080 ENSMUST00000103148.1
ENSMUST00000169807.1
Pcgf2

polycomb group ring finger 2

chr7_-_46795661 0.035 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr11_+_3963970 0.016 ENSMUST00000020705.4
ENSMUST00000109985.1
Pes1

pescadillo homolog 1, containing BRCT domain (zebrafish)


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0009405 pathogenesis(GO:0009405)
2.0 9.9 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
1.9 5.6 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
1.8 7.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.7 5.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.7 10.1 GO:0042045 epithelial fluid transport(GO:0042045)
1.2 12.9 GO:0023041 neuronal signal transduction(GO:0023041)
1.2 18.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.0 3.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
1.0 4.0 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.8 22.5 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.7 4.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.7 3.3 GO:0030242 pexophagy(GO:0030242)
0.7 2.0 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.6 4.8 GO:0070314 G1 to G0 transition(GO:0070314)
0.5 9.6 GO:0021542 dentate gyrus development(GO:0021542)
0.5 1.8 GO:1990743 protein sialylation(GO:1990743)
0.5 4.6 GO:0042118 endothelial cell activation(GO:0042118)
0.4 2.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.4 3.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 5.6 GO:0051764 actin crosslink formation(GO:0051764)
0.4 8.4 GO:0043030 regulation of macrophage activation(GO:0043030)
0.4 1.8 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.4 1.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 0.9 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 2.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 2.5 GO:0030035 microspike assembly(GO:0030035)
0.3 1.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 1.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.3 1.8 GO:0090527 actin filament reorganization(GO:0090527)
0.2 10.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 1.7 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.2 1.4 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.2 0.9 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 2.9 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 2.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 6.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.2 1.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 9.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.2 1.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 3.8 GO:0015813 L-glutamate transport(GO:0015813)
0.1 1.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 15.7 GO:0098792 xenophagy(GO:0098792)
0.1 3.5 GO:0097320 membrane tubulation(GO:0097320)
0.1 2.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.7 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.0 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.7 GO:0015808 L-alanine transport(GO:0015808)
0.1 1.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 2.8 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 1.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 1.2 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 5.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.2 GO:0048747 muscle fiber development(GO:0048747)
0.0 1.0 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 6.3 GO:0006914 autophagy(GO:0006914)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0031088 platelet dense granule membrane(GO:0031088)
3.3 9.9 GO:0043512 inhibin A complex(GO:0043512)
1.0 3.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.7 10.1 GO:0042581 specific granule(GO:0042581)
0.6 6.8 GO:0043083 synaptic cleft(GO:0043083)
0.3 12.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 3.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 3.1 GO:0045095 keratin filament(GO:0045095)
0.2 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 22.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 7.7 GO:0048786 presynaptic active zone(GO:0048786)
0.2 1.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 1.7 GO:0030008 TRAPP complex(GO:0030008)
0.2 5.2 GO:0030673 axolemma(GO:0030673)
0.1 1.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 5.6 GO:0031941 filamentous actin(GO:0031941)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 8.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.4 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 6.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 21.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.5 GO:0030175 filopodium(GO:0030175)
0.0 1.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.0 GO:0000502 proteasome complex(GO:0000502)
0.0 9.3 GO:0005874 microtubule(GO:0005874)
0.0 0.9 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.8 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.8 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.4 GO:0016607 nuclear speck(GO:0016607)
0.0 4.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.5 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
3.4 10.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.8 7.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.6 9.9 GO:0070699 type II activin receptor binding(GO:0070699)
1.4 5.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.1 4.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.0 6.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.7 6.6 GO:0015643 toxic substance binding(GO:0015643)
0.7 2.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.6 5.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 4.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.4 3.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.4 2.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.4 5.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 1.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 6.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 12.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 2.0 GO:0070728 leucine binding(GO:0070728)
0.3 4.7 GO:0042608 T cell receptor binding(GO:0042608)
0.2 0.7 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 1.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 10.1 GO:0045296 cadherin binding(GO:0045296)
0.2 2.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 3.8 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 0.7 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 1.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 8.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 2.9 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 8.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.2 GO:0008009 chemokine activity(GO:0008009)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 8.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 2.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 5.2 GO:0008017 microtubule binding(GO:0008017)
0.0 1.8 GO:0032947 protein complex scaffold(GO:0032947)
0.0 2.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 6.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 9.8 GO:0003682 chromatin binding(GO:0003682)
0.0 3.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)