Motif ID: Hoxa13

Z-value: 0.654


Transcription factors associated with Hoxa13:

Gene SymbolEntrez IDGene Name
Hoxa13 ENSMUSG00000038203.12 Hoxa13



Activity profile for motif Hoxa13.

activity profile for motif Hoxa13


Sorted Z-values histogram for motif Hoxa13

Sorted Z-values for motif Hoxa13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa13

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_45503282 4.173 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chrY_-_1286563 4.135 ENSMUST00000091190.5
 Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr19_+_44493472 4.090 ENSMUST00000041163.4
 Wnt8b
wingless related MMTV integration site 8b
chr4_-_133967296 3.739 ENSMUST00000105893.1
 Hmgn2
high mobility group nucleosomal binding domain 2
chr14_+_65805832 3.683 ENSMUST00000022612.3
 Pbk
PDZ binding kinase
chr14_-_47411666 3.663 ENSMUST00000111778.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr5_+_92809372 3.411 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr17_+_75178797 3.395 ENSMUST00000112516.1
ENSMUST00000135447.1
 Ltbp1

latent transforming growth factor beta binding protein 1

chr5_-_28467093 3.275 ENSMUST00000002708.3
 Shh
sonic hedgehog
chr2_-_129297205 3.263 ENSMUST00000052708.6
 Ckap2l
cytoskeleton associated protein 2-like
chr14_+_65806066 3.122 ENSMUST00000139644.1
 Pbk
PDZ binding kinase
chr3_-_88410295 3.063 ENSMUST00000056370.7
 Pmf1
polyamine-modulated factor 1
chr17_+_75178911 3.017 ENSMUST00000112514.1
 Ltbp1
latent transforming growth factor beta binding protein 1
chr2_-_18048784 3.007 ENSMUST00000142856.1
 Skida1
SKI/DACH domain containing 1
chr9_+_65890237 2.908 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr15_+_25773985 2.840 ENSMUST00000125667.1
 Myo10
myosin X
chr12_-_54986328 2.808 ENSMUST00000038926.6
 Baz1a
bromodomain adjacent to zinc finger domain 1A
chr16_-_18811972 2.796 ENSMUST00000000028.7
ENSMUST00000115585.1
 Cdc45

cell division cycle 45

chrX_+_141475385 2.757 ENSMUST00000112931.1
ENSMUST00000112930.1
 Col4a5

collagen, type IV, alpha 5

chr3_-_49757257 2.753 ENSMUST00000035931.7
 Pcdh18
protocadherin 18

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 155 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.6 GO:0008360 regulation of cell shape(GO:0008360)
0.1 7.4 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 7.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.2 6.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.2 6.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 4.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
1.4 4.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 3.8 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2 3.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.9 3.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
1.1 3.3 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2 3.3 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.2 3.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 3.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 2.9 GO:0019985 translesion synthesis(GO:0019985)
0.9 2.8 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 2.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.5 2.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 2.4 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.5 2.4 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 6.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.1 5.5 GO:0008623 CHRAC(GO:0008623)
1.4 4.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 4.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 4.0 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.1 3.9 GO:0016459 myosin complex(GO:0016459)
0.1 3.8 GO:0000791 euchromatin(GO:0000791)
0.3 3.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 3.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.7 3.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 3.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.5 GO:0043296 apical junction complex(GO:0043296)
0.1 3.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.5 3.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 3.1 GO:0016607 nuclear speck(GO:0016607)
0.9 2.8 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.6 2.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.7 2.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 2.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.4 2.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.5 GO:0051015 actin filament binding(GO:0051015)
1.6 6.4 GO:0050436 microfibril binding(GO:0050436)
0.1 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.1 GO:0005109 frizzled binding(GO:0005109)
0.1 4.1 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
1.3 3.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 3.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 3.6 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 3.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.5 3.5 GO:0000150 recombinase activity(GO:0000150)
0.7 3.3 GO:0005113 patched binding(GO:0005113)
0.0 2.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.3 2.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 2.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.5 2.7 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.4 2.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 2.6 GO:0042169 SH2 domain binding(GO:0042169)
0.2 2.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 2.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)