Motif ID: Hoxa2
Z-value: 0.898
Transcription factors associated with Hoxa2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hoxa2 | ENSMUSG00000014704.8 | Hoxa2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.0 | 11.9 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 2.8 | 11.0 | GO:0060032 | notochord regression(GO:0060032) |
| 2.3 | 11.3 | GO:0046864 | retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143) |
| 2.1 | 18.9 | GO:1902715 | positive regulation of interferon-gamma secretion(GO:1902715) |
| 1.8 | 12.4 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 1.6 | 6.4 | GO:0032901 | positive regulation of neurotrophin production(GO:0032901) |
| 1.3 | 4.0 | GO:0097401 | synaptic vesicle lumen acidification(GO:0097401) |
| 0.9 | 3.8 | GO:0097374 | sensory neuron axon guidance(GO:0097374) |
| 0.7 | 2.0 | GO:1905065 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
| 0.6 | 1.7 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 0.5 | 2.2 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.5 | 2.0 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 0.5 | 4.1 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.4 | 2.5 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.4 | 2.1 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.4 | 1.2 | GO:0035864 | response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) |
| 0.4 | 2.3 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.4 | 3.5 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.4 | 2.2 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.4 | 1.4 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
| 0.4 | 1.1 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
| 0.3 | 1.4 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.3 | 1.3 | GO:0061038 | uterus morphogenesis(GO:0061038) |
| 0.3 | 1.0 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.3 | 0.3 | GO:2000277 | positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277) |
| 0.3 | 2.2 | GO:0030916 | otic vesicle formation(GO:0030916) semicircular canal morphogenesis(GO:0048752) |
| 0.3 | 0.9 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.3 | 1.4 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 0.3 | 0.8 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
| 0.3 | 0.8 | GO:0009446 | putrescine biosynthetic process(GO:0009446) |
| 0.3 | 0.8 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.2 | 2.3 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.2 | 0.7 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.2 | 0.7 | GO:1902713 | regulation of interferon-gamma secretion(GO:1902713) |
| 0.2 | 2.4 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.2 | 0.6 | GO:0060737 | prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) |
| 0.2 | 0.6 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.2 | 0.6 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.2 | 0.8 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.2 | 0.6 | GO:0090234 | regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234) |
| 0.2 | 0.8 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
| 0.2 | 1.1 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.2 | 1.4 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.2 | 1.0 | GO:0070474 | positive regulation of uterine smooth muscle contraction(GO:0070474) |
| 0.2 | 1.5 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 0.2 | 0.7 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
| 0.2 | 3.0 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.2 | 0.5 | GO:0051030 | snRNA transport(GO:0051030) |
| 0.2 | 0.8 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.2 | 1.2 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.2 | 3.2 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.2 | 4.3 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.2 | 1.3 | GO:0006561 | proline biosynthetic process(GO:0006561) |
| 0.2 | 1.9 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.2 | 0.6 | GO:0002741 | positive regulation of cytokine secretion involved in immune response(GO:0002741) |
| 0.1 | 0.4 | GO:0097278 | complement-dependent cytotoxicity(GO:0097278) |
| 0.1 | 1.0 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.1 | 0.4 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 0.1 | 0.5 | GO:0035511 | oxidative DNA demethylation(GO:0035511) |
| 0.1 | 1.8 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.1 | 2.5 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.1 | 9.1 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.1 | 0.5 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.1 | 0.6 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 0.1 | 2.6 | GO:0007614 | short-term memory(GO:0007614) |
| 0.1 | 1.3 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.1 | 3.6 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.1 | 2.1 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 1.0 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 0.6 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
| 0.1 | 0.5 | GO:0072610 | interleukin-12 secretion(GO:0072610) regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184) |
| 0.1 | 2.1 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.1 | 2.3 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 0.5 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.1 | 9.2 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.1 | 0.7 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
| 0.1 | 1.0 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.1 | 0.4 | GO:0003211 | cardiac ventricle formation(GO:0003211) |
| 0.1 | 0.8 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.1 | 0.3 | GO:0061156 | pulmonary artery morphogenesis(GO:0061156) |
| 0.1 | 2.1 | GO:0000303 | response to superoxide(GO:0000303) |
| 0.1 | 0.3 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.1 | 0.1 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.1 | 0.3 | GO:0021775 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
| 0.1 | 0.5 | GO:0032196 | transposition(GO:0032196) |
| 0.1 | 3.6 | GO:0048844 | artery morphogenesis(GO:0048844) |
| 0.1 | 0.3 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 0.1 | 1.0 | GO:0010388 | cullin deneddylation(GO:0010388) |
| 0.1 | 0.7 | GO:0039702 | viral budding via host ESCRT complex(GO:0039702) |
| 0.1 | 0.4 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.1 | 4.9 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.1 | 1.8 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
| 0.1 | 3.6 | GO:0007051 | spindle organization(GO:0007051) |
| 0.1 | 0.4 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
| 0.1 | 2.4 | GO:0021591 | ventricular system development(GO:0021591) |
| 0.1 | 0.7 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.1 | 0.2 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 0.1 | 1.2 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.1 | 2.5 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.1 | 0.6 | GO:0001711 | endodermal cell fate commitment(GO:0001711) |
| 0.1 | 0.5 | GO:0032471 | negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) positive regulation of mitochondrial calcium ion concentration(GO:0051561) |
| 0.0 | 1.1 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
| 0.0 | 2.1 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.0 | 2.2 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
| 0.0 | 0.8 | GO:2000269 | regulation of fibroblast apoptotic process(GO:2000269) |
| 0.0 | 0.5 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
| 0.0 | 0.4 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.5 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.0 | 0.2 | GO:0046322 | negative regulation of fatty acid oxidation(GO:0046322) |
| 0.0 | 0.5 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.0 | 0.4 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.0 | 0.6 | GO:0031100 | organ regeneration(GO:0031100) |
| 0.0 | 0.8 | GO:0051127 | positive regulation of actin nucleation(GO:0051127) |
| 0.0 | 0.7 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.0 | 1.5 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
| 0.0 | 0.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.9 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.0 | 1.0 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.3 | GO:0045056 | transcytosis(GO:0045056) |
| 0.0 | 1.0 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 2.3 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 2.5 | GO:0009566 | fertilization(GO:0009566) |
| 0.0 | 0.4 | GO:0051984 | positive regulation of chromosome segregation(GO:0051984) |
| 0.0 | 1.2 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 2.5 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 0.4 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.0 | 2.2 | GO:0042542 | response to hydrogen peroxide(GO:0042542) |
| 0.0 | 1.2 | GO:0043010 | camera-type eye development(GO:0043010) |
| 0.0 | 1.3 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.0 | 0.5 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
| 0.0 | 0.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.8 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
| 0.0 | 0.2 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.3 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.0 | 1.2 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.0 | 0.6 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.0 | 1.7 | GO:0001843 | neural tube closure(GO:0001843) tube closure(GO:0060606) |
| 0.0 | 0.1 | GO:0070813 | hydrogen sulfide metabolic process(GO:0070813) |
| 0.0 | 4.2 | GO:0007067 | mitotic nuclear division(GO:0007067) |
| 0.0 | 0.0 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.0 | 0.1 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
| 0.0 | 0.4 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
| 0.0 | 0.3 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
| 0.0 | 0.3 | GO:0021692 | cerebellar Purkinje cell layer morphogenesis(GO:0021692) |
| 0.0 | 0.4 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 0.0 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
| 0.0 | 0.1 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.0 | 0.2 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 0.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.1 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 1.0 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 0.0 | GO:2000569 | T-helper 2 cell activation(GO:0035712) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
| 0.0 | 0.8 | GO:0000077 | DNA damage checkpoint(GO:0000077) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 12.9 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.8 | 11.0 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.7 | 2.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.6 | 2.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.5 | 1.5 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.4 | 1.8 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
| 0.3 | 2.7 | GO:0030478 | actin cap(GO:0030478) |
| 0.3 | 1.4 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.2 | 0.7 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 2.2 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.2 | 1.4 | GO:0001740 | Barr body(GO:0001740) |
| 0.2 | 4.0 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.2 | 1.2 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.2 | 2.0 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.1 | 1.3 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 2.1 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.1 | 1.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 0.7 | GO:0000938 | GARP complex(GO:0000938) |
| 0.1 | 0.3 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.1 | 1.0 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.1 | 0.5 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.1 | 0.4 | GO:0033093 | multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093) |
| 0.1 | 1.3 | GO:0016460 | myosin II complex(GO:0016460) |
| 0.1 | 1.0 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 5.5 | GO:0005776 | autophagosome(GO:0005776) |
| 0.1 | 0.6 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.3 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 0.6 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 0.7 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.1 | 6.4 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 0.5 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 2.2 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 2.1 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 0.8 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 1.0 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.1 | 1.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 0.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.1 | 0.4 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
| 0.1 | 3.5 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 5.8 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.9 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.4 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 1.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.6 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 0.8 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.3 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 0.6 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 1.1 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 4.5 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 3.3 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.4 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 1.0 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 0.3 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 1.2 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 1.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 3.7 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 2.4 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 2.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.0 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 3.9 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.0 | 0.9 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 1.7 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 0.9 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 1.3 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.6 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 0.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 2.7 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 0.1 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.0 | 1.5 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.0 | 0.4 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.0 | 0.1 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.0 | 1.2 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
| 0.0 | 0.4 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 1.0 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 2.1 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.2 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 1.8 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 0.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 21.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 1.4 | 4.1 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 1.3 | 4.0 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.8 | 6.4 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.7 | 2.2 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
| 0.7 | 11.9 | GO:0001848 | complement binding(GO:0001848) |
| 0.5 | 2.5 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.5 | 2.0 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.4 | 1.3 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.4 | 11.3 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.4 | 1.2 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
| 0.4 | 1.8 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.4 | 1.4 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
| 0.3 | 2.1 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.3 | 1.6 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 0.3 | 1.3 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.3 | 1.9 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.3 | 0.8 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
| 0.2 | 2.0 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.2 | 0.7 | GO:0048019 | receptor antagonist activity(GO:0048019) |
| 0.2 | 0.7 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.2 | 1.1 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.2 | 8.6 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.2 | 0.6 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.2 | 0.6 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.2 | 0.5 | GO:0051747 | cytosine C-5 DNA demethylase activity(GO:0051747) |
| 0.2 | 0.4 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 0.2 | 2.1 | GO:0070513 | death domain binding(GO:0070513) |
| 0.2 | 1.1 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.2 | 0.5 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 0.2 | 4.6 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.2 | 0.8 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.1 | 1.0 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.1 | 0.7 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 2.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 1.5 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.6 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 0.1 | 1.8 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.1 | 0.3 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
| 0.1 | 2.2 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.1 | 0.8 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.1 | 3.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 0.3 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.1 | 1.2 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
| 0.1 | 1.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 1.8 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.1 | 0.7 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.1 | 0.6 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.1 | 1.3 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 1.8 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.1 | 0.7 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 2.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 2.8 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.1 | 1.0 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.1 | 0.7 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
| 0.1 | 1.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 0.3 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.1 | 0.5 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 1.9 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
| 0.1 | 1.0 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.1 | 1.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 1.7 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 3.2 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 1.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 1.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.3 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 0.4 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.5 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 1.0 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 2.3 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 3.0 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 0.3 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.0 | 2.5 | GO:0019842 | vitamin binding(GO:0019842) |
| 0.0 | 0.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.1 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 0.0 | 0.6 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 0.2 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 12.7 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 0.5 | GO:0042556 | cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 0.0 | 0.5 | GO:0032552 | pyrimidine nucleotide binding(GO:0019103) deoxyribonucleotide binding(GO:0032552) |
| 0.0 | 1.6 | GO:0016408 | C-acyltransferase activity(GO:0016408) |
| 0.0 | 0.2 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 4.8 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.1 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.0 | 0.3 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.0 | 0.3 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 1.0 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.0 | 0.2 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 0.2 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 1.0 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 0.7 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 1.2 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.1 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.0 | 1.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.3 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.4 | GO:0019707 | protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.3 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.6 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 10.1 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 0.0 | 0.5 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.1 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.0 | 3.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.6 | GO:1990782 | protein tyrosine kinase binding(GO:1990782) |
| 0.0 | 0.2 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
| 0.0 | 0.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.2 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 1.0 | GO:0042393 | histone binding(GO:0042393) |
