Motif ID: Hoxa4

Z-value: 0.764


Transcription factors associated with Hoxa4:

Gene SymbolEntrez IDGene Name
Hoxa4 ENSMUSG00000000942.10 Hoxa4



Activity profile for motif Hoxa4.

activity profile for motif Hoxa4


Sorted Z-values histogram for motif Hoxa4

Sorted Z-values for motif Hoxa4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_80802789 8.664 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr2_+_90885860 7.609 ENSMUST00000111466.2
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr2_+_170731807 6.613 ENSMUST00000029075.4
Dok5
docking protein 5
chr5_+_17574726 5.590 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr14_-_79771305 4.875 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr4_+_144892813 4.777 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr1_+_19103022 4.617 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr5_-_84417359 4.567 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr2_-_77519565 4.564 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr2_+_71528657 4.388 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr11_+_57011945 4.337 ENSMUST00000094179.4
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_+_57011798 4.279 ENSMUST00000036315.9
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr4_+_119814495 4.204 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr12_+_29528382 4.127 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr4_+_144893077 4.013 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chrX_+_159840463 3.729 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr4_+_144893127 3.679 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr18_+_37355271 3.663 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr18_+_37489465 3.637 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr18_+_37435602 3.524 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 17.5 GO:0001919 regulation of receptor recycling(GO:0001919)
1.2 13.4 GO:0042572 retinol metabolic process(GO:0042572)
0.2 12.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 7.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.6 6.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.8 5.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.5 5.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
1.7 5.0 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.0 5.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 4.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.8 4.6 GO:0072318 clathrin coat disassembly(GO:0072318)
1.5 4.4 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.1 4.4 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 3.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 3.7 GO:0006089 lactate metabolic process(GO:0006089)
0.0 3.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.2 3.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
1.0 2.9 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 2.9 GO:0008542 visual learning(GO:0008542)
0.6 2.8 GO:0046684 response to pyrethroid(GO:0046684)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 18.3 GO:0005911 cell-cell junction(GO:0005911)
0.5 8.7 GO:0032279 asymmetric synapse(GO:0032279)
1.4 8.6 GO:0044308 axonal spine(GO:0044308)
0.1 8.0 GO:0042641 actomyosin(GO:0042641)
0.1 5.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 5.1 GO:0060076 excitatory synapse(GO:0060076)
0.0 2.9 GO:0005871 kinesin complex(GO:0005871)
0.2 2.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.6 2.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.7 2.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 2.0 GO:0030667 secretory granule membrane(GO:0030667)
0.2 1.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.7 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.5 17.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.8 12.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 5.8 GO:0005509 calcium ion binding(GO:0005509)
0.5 5.6 GO:0038191 neuropilin binding(GO:0038191)
0.7 5.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 5.0 GO:0030275 LRR domain binding(GO:0030275)
0.1 4.6 GO:0002039 p53 binding(GO:0002039)
0.0 4.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 4.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 4.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 4.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 4.0 GO:0003779 actin binding(GO:0003779)
0.1 3.7 GO:0045296 cadherin binding(GO:0045296)
0.1 3.1 GO:0005158 insulin receptor binding(GO:0005158)
0.2 2.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.8 GO:0031402 sodium ion binding(GO:0031402)
0.2 2.7 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 2.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.6 2.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)