Motif ID: Hoxa5

Z-value: 0.811


Transcription factors associated with Hoxa5:

Gene SymbolEntrez IDGene Name
Hoxa5 ENSMUSG00000038253.6 Hoxa5



Activity profile for motif Hoxa5.

activity profile for motif Hoxa5


Sorted Z-values histogram for motif Hoxa5

Sorted Z-values for motif Hoxa5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_88278085 5.872 ENSMUST00000032779.5
ENSMUST00000128791.1
 Ctsc

cathepsin C

chr8_+_57455898 5.368 ENSMUST00000034023.3
 Scrg1
scrapie responsive gene 1
chrX_+_66653003 5.168 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr17_-_31636631 5.122 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
 Cbs


cystathionine beta-synthase


chr4_+_136143497 5.075 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr11_+_16752203 4.962 ENSMUST00000102884.3
ENSMUST00000020329.6
 Egfr

epidermal growth factor receptor

chr18_-_80986578 4.941 ENSMUST00000057950.7
 Sall3
sal-like 3 (Drosophila)
chr19_+_38481057 4.821 ENSMUST00000182481.1
 Plce1
phospholipase C, epsilon 1
chr10_+_57784914 4.467 ENSMUST00000165013.1
 Fabp7
fatty acid binding protein 7, brain
chr9_+_37367354 4.296 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr2_+_14388316 4.296 ENSMUST00000114731.1
ENSMUST00000082290.7
 Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr10_-_13324250 3.991 ENSMUST00000105543.1
 Phactr2
phosphatase and actin regulator 2
chr7_+_110221697 3.961 ENSMUST00000033325.7
 Swap70
SWA-70 protein
chr1_+_104768510 3.823 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr15_+_25773985 3.788 ENSMUST00000125667.1
 Myo10
myosin X
chr2_+_70562854 3.766 ENSMUST00000130998.1
 Gad1
glutamate decarboxylase 1
chr10_-_127341583 3.721 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr5_+_3343893 3.538 ENSMUST00000165117.1
 Cdk6
cyclin-dependent kinase 6
chr14_-_47418407 3.535 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr9_+_94669876 3.523 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 206 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 7.2 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.2 5.9 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.8 5.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5 5.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 5.5 GO:0035136 forelimb morphogenesis(GO:0035136)
0.1 5.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 5.1 GO:0071398 cellular response to fatty acid(GO:0071398)
0.1 5.1 GO:0050728 negative regulation of inflammatory response(GO:0050728)
1.2 5.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
1.0 5.0 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 4.7 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.2 4.5 GO:0060134 prepulse inhibition(GO:0060134)
0.3 4.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.8 4.0 GO:1902309 positive regulation of mast cell chemotaxis(GO:0060754) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 3.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 3.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.9 3.7 GO:0060032 notochord regression(GO:0060032)
0.0 3.6 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
1.2 3.5 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.5 3.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.7 GO:0000775 chromosome, centromeric region(GO:0000775)
0.2 5.6 GO:0060077 inhibitory synapse(GO:0060077)
1.7 5.0 GO:0031983 vesicle lumen(GO:0031983)
0.0 4.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 4.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 4.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.8 GO:0016459 myosin complex(GO:0016459)
0.2 3.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 3.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 3.5 GO:0005657 replication fork(GO:0005657)
0.3 3.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 3.3 GO:0097542 ciliary tip(GO:0097542)
0.1 3.1 GO:0034451 centriolar satellite(GO:0034451)
0.3 3.0 GO:0008278 cohesin complex(GO:0008278)
0.1 2.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 2.6 GO:0098536 deuterosome(GO:0098536)
0.1 2.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.5 2.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 2.5 GO:0031262 Ndc80 complex(GO:0031262)
0.3 2.4 GO:0032009 early phagosome(GO:0032009)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 146 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.1 GO:0005504 fatty acid binding(GO:0005504)
0.3 6.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 5.9 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.8 5.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 5.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 5.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 5.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.7 5.1 GO:0098809 nitrite reductase activity(GO:0098809)
1.7 5.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 4.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.8 GO:0003774 motor activity(GO:0003774)
0.0 3.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.4 3.5 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 3.5 GO:0030332 cyclin binding(GO:0030332)
0.1 3.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.4 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
1.1 3.3 GO:0043912 D-lysine oxidase activity(GO:0043912)
1.1 3.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.8 3.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 3.1 GO:0003743 translation initiation factor activity(GO:0003743)