Motif ID: Hoxa6

Z-value: 0.872


Transcription factors associated with Hoxa6:

Gene SymbolEntrez IDGene Name
Hoxa6 ENSMUSG00000043219.8 Hoxa6



Activity profile for motif Hoxa6.

activity profile for motif Hoxa6


Sorted Z-values histogram for motif Hoxa6

Sorted Z-values for motif Hoxa6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa6

PNG image of the network

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Top targets:


Showing 1 to 20 of 183 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_71528657 22.416 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr19_-_59170978 11.555 ENSMUST00000172821.2
 Vax1
ventral anterior homeobox containing gene 1
chr14_-_118052235 11.380 ENSMUST00000022725.2
 Dct
dopachrome tautomerase
chr8_-_46294592 9.668 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr1_-_163313661 9.143 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
 Prrx1


paired related homeobox 1


chr16_+_42907563 8.421 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr7_-_37773555 7.665 ENSMUST00000176534.1
 Zfp536
zinc finger protein 536
chr7_-_116038734 7.300 ENSMUST00000166877.1
 Sox6
SRY-box containing gene 6
chr1_+_6730051 6.982 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr6_+_15185456 6.397 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
 Foxp2



forkhead box P2



chr13_-_103764502 6.283 ENSMUST00000074616.5
 Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr9_+_118478344 6.165 ENSMUST00000035020.8
 Eomes
eomesodermin homolog (Xenopus laevis)
chr4_-_110292719 6.139 ENSMUST00000106601.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr9_+_118478182 5.524 ENSMUST00000111763.1
 Eomes
eomesodermin homolog (Xenopus laevis)
chr10_-_42583628 5.344 ENSMUST00000019938.4
 Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr4_+_11579647 5.087 ENSMUST00000180239.1
 Fsbp
fibrinogen silencer binding protein
chr2_+_38341068 5.049 ENSMUST00000133661.1
 Lhx2
LIM homeobox protein 2
chr18_-_84086379 4.963 ENSMUST00000060303.8
 Tshz1
teashirt zinc finger family member 1
chr2_+_70474923 4.938 ENSMUST00000100043.2
 Sp5
trans-acting transcription factor 5
chr2_+_20737306 4.748 ENSMUST00000114606.1
ENSMUST00000114608.1
 Etl4

enhancer trap locus 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.5 22.4 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.5 16.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.2 14.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
3.9 11.7 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.4 11.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
1.9 11.4 GO:0006570 tyrosine metabolic process(GO:0006570)
0.7 11.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.0 10.6 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 9.4 GO:0043488 regulation of mRNA stability(GO:0043488)
1.3 9.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.0 8.0 GO:0048664 neuron fate determination(GO:0048664)
0.3 7.7 GO:0035855 megakaryocyte development(GO:0035855)
0.6 7.1 GO:0060539 diaphragm development(GO:0060539)
0.7 6.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.2 6.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 6.2 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
1.5 6.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.2 6.0 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.2 5.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.5 5.3 GO:0002118 aggressive behavior(GO:0002118)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 45.3 GO:0005667 transcription factor complex(GO:0005667)
0.5 11.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.7 9.4 GO:0042788 polysomal ribosome(GO:0042788)
0.8 7.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.5 7.3 GO:0043205 fibril(GO:0043205)
0.0 6.3 GO:0005681 spliceosomal complex(GO:0005681)
0.7 6.2 GO:0030478 actin cap(GO:0030478)
1.9 5.8 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 5.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
1.0 4.8 GO:0008623 CHRAC(GO:0008623)
0.4 2.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 2.5 GO:0097440 apical dendrite(GO:0097440)
0.0 2.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.1 1.1 GO:0033269 internode region of axon(GO:0033269)
0.1 0.8 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.2 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 55.3 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.3 45.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 15.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
1.4 11.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.8 11.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.6 9.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 9.4 GO:0017091 AU-rich element binding(GO:0017091)
1.1 9.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 8.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.5 6.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
1.4 5.8 GO:0050436 microfibril binding(GO:0050436)
1.0 4.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 4.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 4.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 3.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 3.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 3.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.4 3.1 GO:1990188 euchromatin binding(GO:1990188)
0.0 2.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)