Motif ID: Hoxa6

Z-value: 0.872


Transcription factors associated with Hoxa6:

Gene SymbolEntrez IDGene Name
Hoxa6 ENSMUSG00000043219.8 Hoxa6



Activity profile for motif Hoxa6.

activity profile for motif Hoxa6


Sorted Z-values histogram for motif Hoxa6

Sorted Z-values for motif Hoxa6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_71528657 22.416 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr19_-_59170978 11.555 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr14_-_118052235 11.380 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr8_-_46294592 9.668 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr1_-_163313661 9.143 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr16_+_42907563 8.421 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr7_-_37773555 7.665 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr7_-_116038734 7.300 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr1_+_6730051 6.982 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr6_+_15185456 6.397 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr13_-_103764502 6.283 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr9_+_118478344 6.165 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr4_-_110292719 6.139 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr9_+_118478182 5.524 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr10_-_42583628 5.344 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr4_+_11579647 5.087 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr2_+_38341068 5.049 ENSMUST00000133661.1
Lhx2
LIM homeobox protein 2
chr18_-_84086379 4.963 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr2_+_70474923 4.938 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr2_+_20737306 4.748 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr1_-_165934900 4.366 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr11_-_19018956 4.208 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
Meis1


Meis homeobox 1


chr13_-_97747373 4.198 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_+_181767040 4.167 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr6_+_15196949 4.116 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr14_-_48665098 4.057 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_-_36104060 3.901 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr10_+_88091070 3.884 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr6_+_15185203 3.687 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr11_+_102604370 3.626 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr11_-_19018714 3.520 ENSMUST00000177417.1
Meis1
Meis homeobox 1
chr12_+_38783455 3.459 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr12_-_34528844 3.368 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr2_-_33942111 3.355 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr7_-_37772868 3.305 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr4_-_110287479 3.289 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr7_-_115824699 3.263 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr2_-_18048784 3.200 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr1_+_187997821 3.141 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr1_+_187997835 3.102 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr9_+_120929216 3.086 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chr17_+_75178797 2.997 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr12_+_38783503 2.969 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr2_+_181767283 2.913 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr1_+_6734827 2.903 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr2_-_116067391 2.893 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr15_-_8710734 2.869 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_97584612 2.841 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584605 2.787 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr5_-_106574706 2.783 ENSMUST00000131029.1
ENSMUST00000124394.2
RP24-421H18.1

RP24-421H18.1

chr17_+_75178911 2.756 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr19_+_55894508 2.732 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr1_-_166002613 2.706 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
Pou2f1



POU domain, class 2, transcription factor 1



chr14_+_75455957 2.668 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr1_+_19103022 2.661 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr16_-_88056176 2.642 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
Grik1


glutamate receptor, ionotropic, kainate 1


chr14_-_122451109 2.616 ENSMUST00000081580.2
Gm5089
predicted gene 5089
chr5_+_149678224 2.601 ENSMUST00000100404.3
B3galtl
beta 1,3-galactosyltransferase-like
chr1_-_166002591 2.550 ENSMUST00000111429.4
ENSMUST00000176800.1
Pou2f1

POU domain, class 2, transcription factor 1

chr10_-_92164666 2.549 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr2_-_79456750 2.538 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr12_-_54986363 2.513 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr16_+_43503607 2.431 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr9_-_60141220 2.428 ENSMUST00000034829.5
Thsd4
thrombospondin, type I, domain containing 4
chr14_+_28511344 2.417 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr2_-_18048347 2.407 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr13_-_83729544 2.394 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr9_-_42399709 2.370 ENSMUST00000160940.1
Tecta
tectorin alpha
chr9_-_42399915 2.357 ENSMUST00000042190.7
Tecta
tectorin alpha
chr16_+_43247278 2.294 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr12_-_54986328 2.257 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr13_-_97747399 2.243 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_+_104768510 2.169 ENSMUST00000062528.8
Cdh20
cadherin 20
chr2_+_116067933 2.038 ENSMUST00000156095.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr7_-_73541738 2.026 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr15_-_8710409 2.002 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_51810866 1.964 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr6_+_34598530 1.877 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr11_+_77930800 1.843 ENSMUST00000093995.3
ENSMUST00000000646.7
Sez6

seizure related gene 6

chr2_+_79707780 1.783 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
Ppp1r1c


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr4_-_91399984 1.750 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_-_42168603 1.735 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr5_-_123141067 1.718 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr1_+_6730135 1.672 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr6_+_34598500 1.657 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr3_-_52104891 1.642 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr17_-_58991343 1.590 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr19_+_55895508 1.570 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr6_+_34709442 1.566 ENSMUST00000115021.1
Cald1
caldesmon 1
chr10_-_13388753 1.549 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr16_+_43235856 1.542 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr3_+_76075583 1.490 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr2_-_63184253 1.481 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr10_+_42860348 1.457 ENSMUST00000063063.7
Scml4
sex comb on midleg-like 4 (Drosophila)
chrM_+_7005 1.413 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr3_+_41563356 1.400 ENSMUST00000163764.1
Phf17
PHD finger protein 17
chr4_-_82850721 1.334 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr10_+_42860776 1.287 ENSMUST00000105494.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr4_-_82885148 1.285 ENSMUST00000048430.3
Cer1
cerberus 1 homolog (Xenopus laevis)
chr18_-_13972617 1.231 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr10_+_42860648 1.205 ENSMUST00000105495.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr8_-_67974567 1.188 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chr6_+_34709610 1.145 ENSMUST00000031775.6
Cald1
caldesmon 1
chr14_-_48662740 1.144 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_+_72297895 1.143 ENSMUST00000144111.1
Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr2_-_28916412 1.142 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr10_-_13388830 1.129 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr4_-_21685782 1.105 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr1_-_87394721 1.101 ENSMUST00000113212.3
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr5_+_13399309 1.080 ENSMUST00000030714.7
ENSMUST00000141968.1
Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr19_-_53371766 1.078 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr1_+_137928100 1.068 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr2_-_58052832 1.054 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr18_-_23041641 1.048 ENSMUST00000097651.3
Nol4
nucleolar protein 4
chr5_+_42067960 1.034 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr3_+_102010138 1.013 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr16_+_43363855 1.010 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr18_-_22850738 0.936 ENSMUST00000092015.4
ENSMUST00000069215.6
Nol4

nucleolar protein 4

chr2_-_64097994 0.904 ENSMUST00000131615.2
Fign
fidgetin
chr16_-_64786321 0.889 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr7_-_84679346 0.884 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr9_+_46998931 0.874 ENSMUST00000178065.1
Gm4791
predicted gene 4791
chr13_-_78196373 0.873 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr16_+_43364145 0.854 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr14_-_48667508 0.848 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr18_+_69593361 0.838 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr7_-_49636847 0.831 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr4_-_82705735 0.830 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr7_-_109170308 0.829 ENSMUST00000036992.7
Lmo1
LIM domain only 1
chr3_-_138131356 0.781 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr6_-_55681257 0.756 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr8_-_84773381 0.747 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr4_-_92191749 0.720 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr4_+_128688726 0.710 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr2_-_170194033 0.707 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr8_-_47352348 0.697 ENSMUST00000110367.2
Stox2
storkhead box 2
chr2_-_63184170 0.682 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr8_-_67818284 0.679 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr13_+_80883403 0.672 ENSMUST00000099356.2
Arrdc3
arrestin domain containing 3
chr5_+_13398688 0.629 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_+_34989473 0.612 ENSMUST00000114284.1
ENSMUST00000114285.1
Rgs12

regulator of G-protein signaling 12

chr2_-_72986716 0.600 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr2_-_168767029 0.592 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr17_+_34592248 0.586 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr18_+_42394539 0.566 ENSMUST00000025374.3
Pou4f3
POU domain, class 4, transcription factor 3
chr13_+_44840686 0.531 ENSMUST00000173906.1
Jarid2
jumonji, AT rich interactive domain 2
chr3_+_130180882 0.505 ENSMUST00000106353.1
ENSMUST00000080335.4
Col25a1

collagen, type XXV, alpha 1

chr4_+_107968332 0.492 ENSMUST00000106713.3
Slc1a7
solute carrier family 1 (glutamate transporter), member 7
chr2_-_168767136 0.460 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr5_+_115235836 0.453 ENSMUST00000081497.6
Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr7_+_49910112 0.451 ENSMUST00000056442.5
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr17_+_43952999 0.436 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr2_+_132847719 0.421 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr7_+_131542867 0.421 ENSMUST00000046093.5
Hmx3
H6 homeobox 3
chrM_+_2743 0.401 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr11_+_94044331 0.349 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr9_-_119825456 0.336 ENSMUST00000070617.7
Scn11a
sodium channel, voltage-gated, type XI, alpha
chr1_-_30863256 0.334 ENSMUST00000088310.3
Phf3
PHD finger protein 3
chr2_-_28916668 0.299 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr2_-_168207063 0.299 ENSMUST00000088001.5
Adnp
activity-dependent neuroprotective protein
chr16_-_95459245 0.292 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr16_-_56024628 0.279 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr18_-_54990124 0.252 ENSMUST00000064763.5
Zfp608
zinc finger protein 608
chr12_-_56613270 0.240 ENSMUST00000072631.5
Nkx2-9
NK2 homeobox 9
chr15_+_79690869 0.226 ENSMUST00000046463.8
Gtpbp1
GTP binding protein 1
chr11_-_33203588 0.226 ENSMUST00000037746.6
Tlx3
T cell leukemia, homeobox 3
chr6_-_124840192 0.221 ENSMUST00000024206.5
Gnb3
guanine nucleotide binding protein (G protein), beta 3
chr8_-_67818218 0.220 ENSMUST00000059374.4
Psd3
pleckstrin and Sec7 domain containing 3
chr5_-_123140135 0.217 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr9_-_105521147 0.195 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr10_-_53638269 0.190 ENSMUST00000164393.1
Fam184a
family with sequence similarity 184, member A
chr13_-_28953690 0.185 ENSMUST00000067230.5
Sox4
SRY-box containing gene 4
chr11_+_94044241 0.162 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr18_-_47368446 0.161 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr11_+_94044194 0.140 ENSMUST00000092777.4
ENSMUST00000075695.6
Spag9

sperm associated antigen 9

chr3_-_131344892 0.139 ENSMUST00000090246.4
ENSMUST00000126569.1
Sgms2

sphingomyelin synthase 2

chrM_+_10167 0.107 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr8_-_105568298 0.103 ENSMUST00000005849.5
Agrp
agouti related protein
chr11_+_100320596 0.088 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr3_+_84952146 0.082 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr13_-_18382041 0.076 ENSMUST00000139064.2
ENSMUST00000175703.2
Pou6f2

POU domain, class 6, transcription factor 2

chr11_+_78826575 0.074 ENSMUST00000147875.2
ENSMUST00000141321.1
Lyrm9

LYR motif containing 9

chrM_+_7759 0.067 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.4 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
3.9 11.7 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.9 11.4 GO:0006570 tyrosine metabolic process(GO:0006570)
1.7 5.0 GO:0060023 soft palate development(GO:0060023)
1.5 6.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.4 11.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
1.3 3.9 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
1.3 9.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.2 4.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.2 6.0 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
1.2 14.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
1.0 3.1 GO:0060423 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) negative regulation of mitotic cell cycle, embryonic(GO:0045976) foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
1.0 8.0 GO:0048664 neuron fate determination(GO:0048664)
1.0 10.6 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.8 2.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.8 3.9 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.7 6.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.7 11.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 7.1 GO:0060539 diaphragm development(GO:0060539)
0.6 5.0 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.6 4.3 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.5 5.3 GO:0002118 aggressive behavior(GO:0002118)
0.5 2.7 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.5 16.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 2.6 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.4 1.3 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.4 3.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.4 2.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 2.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 7.7 GO:0035855 megakaryocyte development(GO:0035855)
0.3 0.8 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 4.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 5.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 0.7 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.2 0.8 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 2.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 0.6 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.2 0.2 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.2 6.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 3.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.8 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 2.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 1.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.3 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.6 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 6.2 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 9.4 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.8 GO:0042118 endothelial cell activation(GO:0042118)
0.1 2.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 2.7 GO:0030901 midbrain development(GO:0030901)
0.1 0.5 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.5 GO:0036233 glycine import(GO:0036233)
0.1 0.3 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.8 GO:0021542 dentate gyrus development(GO:0021542)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.8 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 1.0 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 4.9 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.9 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 4.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 2.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 1.3 GO:0022900 electron transport chain(GO:0022900)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.2 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.4 GO:0060135 maternal process involved in female pregnancy(GO:0060135)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.0 4.8 GO:0008623 CHRAC(GO:0008623)
0.8 7.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.7 9.4 GO:0042788 polysomal ribosome(GO:0042788)
0.7 6.2 GO:0030478 actin cap(GO:0030478)
0.5 7.3 GO:0043205 fibril(GO:0043205)
0.5 11.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 2.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.1 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0044299 C-fiber(GO:0044299)
0.1 45.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 2.5 GO:0097440 apical dendrite(GO:0097440)
0.1 0.8 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.0 2.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 6.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 5.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 11.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
1.4 5.8 GO:0050436 microfibril binding(GO:0050436)
1.1 9.1 GO:0071837 HMG box domain binding(GO:0071837)
1.0 4.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.8 11.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.8 2.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.6 9.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 6.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.4 3.1 GO:1990188 euchromatin binding(GO:1990188)
0.4 2.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 1.3 GO:0016015 morphogen activity(GO:0016015)
0.3 45.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 15.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 9.4 GO:0017091 AU-rich element binding(GO:0017091)
0.2 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) TFIIB-class transcription factor binding(GO:0001093)
0.2 1.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 3.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 4.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 3.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 3.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.5 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 3.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 4.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 55.3 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.1 0.4 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.1 0.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.2 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.7 GO:0005507 copper ion binding(GO:0005507)
0.0 1.1 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 8.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)