Motif ID: Hoxa7_Hoxc8
Z-value: 0.461
Transcription factors associated with Hoxa7_Hoxc8:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxa7 | ENSMUSG00000038236.6 | Hoxa7 |
Hoxc8 | ENSMUSG00000001657.6 | Hoxc8 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.1 | 12.3 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.6 | 2.3 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.5 | 9.1 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.2 | 0.6 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.2 | 0.7 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
0.2 | 0.5 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
0.1 | 1.0 | GO:1901162 | serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
0.1 | 0.8 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.1 | 0.8 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.1 | 1.0 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.1 | 0.9 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 1.0 | GO:0097460 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) |
0.1 | 1.3 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 0.4 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.1 | 0.5 | GO:0030242 | pexophagy(GO:0030242) |
0.1 | 0.4 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
0.1 | 3.6 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.1 | 0.2 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.1 | 0.7 | GO:0070307 | lens fiber cell development(GO:0070307) |
0.1 | 1.1 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.1 | 0.7 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
0.1 | 0.1 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
0.1 | 0.2 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.1 | 0.4 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.1 | 0.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.2 | GO:0033762 | response to glucagon(GO:0033762) |
0.0 | 0.1 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.0 | 0.4 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 1.3 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.0 | 0.7 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
0.0 | 0.4 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
0.0 | 0.2 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
0.0 | 0.8 | GO:0032148 | activation of protein kinase B activity(GO:0032148) |
0.0 | 1.0 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
0.0 | 0.5 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.0 | 1.6 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
0.0 | 3.3 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 0.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.0 | 0.3 | GO:0009299 | mRNA transcription(GO:0009299) |
0.0 | 0.9 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.0 | 0.9 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 2.1 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 12.3 | GO:0043205 | fibril(GO:0043205) |
0.3 | 0.8 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.3 | 3.6 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 1.0 | GO:0097433 | dense body(GO:0097433) |
0.1 | 1.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.1 | 0.5 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.1 | 0.3 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 2.0 | GO:0031672 | A band(GO:0031672) |
0.0 | 0.8 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 1.5 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.1 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
0.0 | 0.5 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.4 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
0.0 | 0.4 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.0 | 0.2 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.0 | 9.9 | GO:0005874 | microtubule(GO:0005874) |
0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.2 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
0.0 | 1.1 | GO:0098878 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
0.0 | 0.7 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.5 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 1.2 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 0.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 12.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.4 | 9.1 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.3 | 1.0 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
0.3 | 1.0 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.1 | 0.7 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.1 | 1.0 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.1 | 5.7 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 0.4 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.9 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.1 | 3.6 | GO:0045296 | cadherin binding(GO:0045296) |
0.1 | 0.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 1.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.1 | 0.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.1 | 0.5 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.1 | 1.0 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.0 | 0.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 1.6 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 1.1 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
0.0 | 0.8 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.0 | 1.7 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.0 | 0.1 | GO:0051378 | primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378) |
0.0 | 0.2 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 0.2 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 0.1 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132) |
0.0 | 0.8 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 1.0 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 1.4 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
0.0 | 0.7 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.2 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.0 | 0.5 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.4 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.0 | 3.1 | GO:0003924 | GTPase activity(GO:0003924) |
0.0 | 0.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.5 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |