Motif ID: Hoxa9_Hoxb9
Z-value: 0.448
Transcription factors associated with Hoxa9_Hoxb9:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxa9 | ENSMUSG00000038227.9 | Hoxa9 |
Hoxb9 | ENSMUSG00000020875.8 | Hoxb9 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 4.1 | GO:0019732 | antifungal humoral response(GO:0019732) |
0.4 | 2.1 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
0.4 | 2.0 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
0.3 | 2.5 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
0.3 | 1.5 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
0.3 | 2.9 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
0.2 | 0.7 | GO:0007525 | somatic muscle development(GO:0007525) |
0.2 | 1.2 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.2 | 1.5 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.2 | 0.5 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
0.2 | 0.9 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.1 | 0.4 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
0.1 | 12.7 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.1 | 1.2 | GO:2000821 | regulation of grooming behavior(GO:2000821) |
0.1 | 0.4 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
0.1 | 3.9 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.1 | 0.8 | GO:0023041 | neuronal signal transduction(GO:0023041) |
0.1 | 0.2 | GO:0010898 | positive regulation of triglyceride catabolic process(GO:0010898) |
0.1 | 0.9 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
0.1 | 0.2 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
0.0 | 0.4 | GO:0043313 | regulation of neutrophil degranulation(GO:0043313) |
0.0 | 0.9 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
0.0 | 1.3 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
0.0 | 0.3 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.0 | 0.4 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.0 | 0.3 | GO:0017121 | phospholipid scrambling(GO:0017121) |
0.0 | 0.2 | GO:0032264 | IMP salvage(GO:0032264) |
0.0 | 0.1 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.0 | 0.7 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.6 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
0.0 | 0.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.0 | 0.9 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.0 | 0.1 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.0 | 0.2 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
0.0 | 1.5 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.0 | 0.1 | GO:0001193 | maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193) |
0.0 | 1.1 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
0.0 | 1.2 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 0.2 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
0.0 | 0.0 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.0 | GO:0043512 | inhibin A complex(GO:0043512) |
0.3 | 2.9 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
0.2 | 0.5 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
0.2 | 2.5 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 1.2 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.1 | 1.1 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 11.1 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 0.5 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.1 | 3.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.1 | 1.3 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.1 | 0.4 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 4.1 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 3.3 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 1.5 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.2 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.0 | 0.2 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.0 | 0.4 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 1.6 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.0 | 0.0 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.0 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.3 | 2.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.3 | 1.2 | GO:0008061 | chitin binding(GO:0008061) |
0.3 | 1.5 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.3 | 4.1 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.3 | 0.8 | GO:0004556 | alpha-amylase activity(GO:0004556) |
0.2 | 0.9 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.2 | 2.9 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.2 | 0.7 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
0.2 | 2.1 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.2 | 1.2 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 1.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.1 | 0.6 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 0.4 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
0.1 | 2.5 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.1 | 0.5 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
0.1 | 0.4 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.1 | 0.9 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 1.1 | GO:0032183 | SUMO binding(GO:0032183) |
0.0 | 1.5 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.2 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
0.0 | 0.7 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.0 | 0.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 1.2 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.5 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.0 | 0.4 | GO:0015026 | coreceptor activity(GO:0015026) |
0.0 | 0.3 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.0 | 0.3 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
0.0 | 0.4 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 0.3 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
0.0 | 5.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.2 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.1 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.2 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
0.0 | 0.3 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.0 | 0.5 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
0.0 | 5.8 | GO:0003779 | actin binding(GO:0003779) |
0.0 | 0.0 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.0 | 1.6 | GO:0017124 | SH3 domain binding(GO:0017124) |