Motif ID: Hoxb13

Z-value: 0.706


Transcription factors associated with Hoxb13:

Gene SymbolEntrez IDGene Name
Hoxb13 ENSMUSG00000049604.3 Hoxb13



Activity profile for motif Hoxb13.

activity profile for motif Hoxb13


Sorted Z-values histogram for motif Hoxb13

Sorted Z-values for motif Hoxb13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb13

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_65890237 5.805 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr11_+_120948480 5.109 ENSMUST00000070653.6
Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr15_+_25773985 4.411 ENSMUST00000125667.1
Myo10
myosin X
chr14_-_47411666 4.237 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr8_+_12395287 4.217 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chr12_+_117843873 4.048 ENSMUST00000176735.1
ENSMUST00000177339.1
Cdca7l

cell division cycle associated 7 like

chr3_+_134236483 3.791 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr5_-_28467093 3.694 ENSMUST00000002708.3
Shh
sonic hedgehog
chr4_+_44300876 3.652 ENSMUST00000045607.5
Melk
maternal embryonic leucine zipper kinase
chr15_+_25742314 3.532 ENSMUST00000135981.1
Myo10
myosin X
chr12_+_79297345 3.295 ENSMUST00000079533.5
ENSMUST00000171210.1
Rad51b

RAD51 homolog B

chr16_-_18811972 3.272 ENSMUST00000000028.7
ENSMUST00000115585.1
Cdc45

cell division cycle 45

chr3_-_150073620 3.026 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr9_-_63711969 2.989 ENSMUST00000154323.1
Smad3
SMAD family member 3
chr4_-_117182623 2.959 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr16_+_30065333 2.885 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr14_+_65805832 2.862 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr14_+_50944499 2.849 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr17_-_26095487 2.814 ENSMUST00000025007.5
Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr2_-_129297205 2.807 ENSMUST00000052708.6
Ckap2l
cytoskeleton associated protein 2-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 331 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.7 GO:0046847 filopodium assembly(GO:0046847)
0.2 8.0 GO:0006284 base-excision repair(GO:0006284)
1.2 7.4 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.5 6.3 GO:0019985 translesion synthesis(GO:0019985)
0.3 5.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.3 5.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 5.1 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 5.0 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 5.0 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.0 4.6 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.8 4.5 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 4.4 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.1 4.3 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.3 3.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.3 3.5 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
1.1 3.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.8 3.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.8 3.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.0 3.0 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.6 3.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 164 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 10.5 GO:0016459 myosin complex(GO:0016459)
0.0 8.7 GO:0005730 nucleolus(GO:0005730)
0.8 5.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 5.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.9 4.6 GO:0008623 CHRAC(GO:0008623)
0.3 4.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 4.1 GO:0005938 cell cortex(GO:0005938)
0.1 4.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.8 3.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 3.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 3.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.5 GO:0000776 kinetochore(GO:0000776)
0.0 3.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
1.1 3.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.7 3.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 3.2 GO:0030894 replisome(GO:0030894)
1.0 3.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 3.1 GO:0097452 GAIT complex(GO:0097452)
0.6 3.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 243 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 13.5 GO:0051015 actin filament binding(GO:0051015)
0.0 9.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 6.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 5.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 5.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.8 5.5 GO:0043237 laminin-1 binding(GO:0043237)
0.2 5.2 GO:0071837 HMG box domain binding(GO:0071837)
1.6 4.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.7 4.9 GO:0000150 recombinase activity(GO:0000150)
0.8 4.6 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 4.6 GO:0005109 frizzled binding(GO:0005109)
0.1 4.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 4.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 3.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 3.7 GO:0070888 E-box binding(GO:0070888)
0.2 3.4 GO:0016805 dipeptidase activity(GO:0016805)
1.1 3.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.4 3.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 3.3 GO:0003746 translation elongation factor activity(GO:0003746)
1.1 3.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)