Motif ID: Hoxb2_Dlx2
Z-value: 0.964


Transcription factors associated with Hoxb2_Dlx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Dlx2 | ENSMUSG00000023391.7 | Dlx2 |
Hoxb2 | ENSMUSG00000075588.5 | Hoxb2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Dlx2 | mm10_v2_chr2_-_71546745_71546758 | 0.86 | 3.4e-21 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 129 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
9.9 | 29.7 | GO:0021893 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) |
0.8 | 24.5 | GO:0007638 | mechanosensory behavior(GO:0007638) |
6.0 | 24.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
5.3 | 21.2 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.5 | 14.1 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
0.1 | 13.8 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
2.9 | 11.4 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
3.6 | 10.7 | GO:0090425 | hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
1.2 | 9.9 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.7 | 9.5 | GO:0007530 | sex determination(GO:0007530) |
0.6 | 9.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.7 | 9.2 | GO:0031017 | exocrine pancreas development(GO:0031017) |
0.6 | 9.2 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
0.1 | 9.1 | GO:0030326 | embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113) |
0.3 | 8.5 | GO:0071398 | cellular response to fatty acid(GO:0071398) |
2.8 | 8.4 | GO:0048818 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
1.4 | 8.4 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
1.3 | 8.1 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
0.1 | 7.6 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 7.3 | GO:0007059 | chromosome segregation(GO:0007059) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 59 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 86.5 | GO:0005634 | nucleus(GO:0005634) |
1.4 | 24.1 | GO:0043205 | fibril(GO:0043205) |
0.1 | 22.4 | GO:0005667 | transcription factor complex(GO:0005667) |
0.2 | 13.2 | GO:0016459 | myosin complex(GO:0016459) |
2.0 | 11.8 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.7 | 10.9 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 10.4 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 9.6 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.3 | 9.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.2 | 9.1 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
1.0 | 8.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
1.4 | 8.1 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.0 | 8.0 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.3 | 7.9 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.1 | 5.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.2 | 5.0 | GO:0060077 | inhibitory synapse(GO:0060077) |
1.6 | 4.9 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
0.2 | 4.3 | GO:0002102 | podosome(GO:0002102) |
2.0 | 4.0 | GO:0071953 | elastic fiber(GO:0071953) |
0.3 | 3.7 | GO:0005915 | zonula adherens(GO:0005915) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 104 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 48.4 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
0.2 | 47.1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
4.8 | 24.1 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.1 | 13.5 | GO:0000987 | core promoter proximal region sequence-specific DNA binding(GO:0000987) |
0.3 | 13.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.5 | 12.6 | GO:0001968 | fibronectin binding(GO:0001968) |
0.2 | 12.3 | GO:0030507 | spectrin binding(GO:0030507) |
0.1 | 12.0 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.9 | 11.8 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
2.3 | 11.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 11.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
1.3 | 10.7 | GO:0050693 | LBD domain binding(GO:0050693) |
1.0 | 10.3 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
1.2 | 9.9 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.4 | 9.6 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 8.9 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
0.3 | 8.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.5 | 8.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.6 | 8.1 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.3 | 7.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |