Motif ID: Hoxb3

Z-value: 1.123


Transcription factors associated with Hoxb3:

Gene SymbolEntrez IDGene Name
Hoxb3 ENSMUSG00000048763.5 Hoxb3



Activity profile for motif Hoxb3.

activity profile for motif Hoxb3


Sorted Z-values histogram for motif Hoxb3

Sorted Z-values for motif Hoxb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb3

PNG image of the network

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Top targets:


Showing 1 to 20 of 126 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_8710734 18.374 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_170009892 18.117 ENSMUST00000180251.1
 Gm21887
predicted gene, 21887
chr15_-_8710409 16.460 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_-_54661870 11.975 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chrY_+_90785442 11.691 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
 Erdr1


erythroid differentiation regulator 1


chr9_-_54661666 9.101 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr12_+_74288735 8.479 ENSMUST00000095617.1
 1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr19_+_3323301 7.651 ENSMUST00000025835.4
 Cpt1a
carnitine palmitoyltransferase 1a, liver
chr12_+_84069325 7.523 ENSMUST00000046422.4
ENSMUST00000072505.4
 Acot5

acyl-CoA thioesterase 5

chrY_+_90784738 7.087 ENSMUST00000179483.1
 Erdr1
erythroid differentiation regulator 1
chr2_-_156392829 7.012 ENSMUST00000088578.2
 2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr4_-_14621805 6.789 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chrX_+_170010744 6.350 ENSMUST00000178789.1
 Gm21887
predicted gene, 21887
chr5_+_63812447 5.836 ENSMUST00000081747.3
 0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr5_+_134932351 5.659 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
 Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr11_+_101665541 5.224 ENSMUST00000039388.2
 Arl4d
ADP-ribosylation factor-like 4D
chr2_+_116067213 5.180 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr5_-_77115145 5.178 ENSMUST00000081964.5
 Hopx
HOP homeobox
chr3_-_121263314 5.089 ENSMUST00000029777.7
 Tmem56
transmembrane protein 56
chr10_-_83648631 4.869 ENSMUST00000146876.2
ENSMUST00000176294.1
 Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.7 34.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.7 22.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.2 16.3 GO:0035019 somatic stem cell population maintenance(GO:0035019)
1.5 10.4 GO:0019532 oxalate transport(GO:0019532)
0.7 7.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
1.9 7.5 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 5.5 GO:0032259 methylation(GO:0032259)
0.9 5.4 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 4.9 GO:0034501 protein localization to kinetochore(GO:0034501)
0.5 4.8 GO:0090527 actin filament reorganization(GO:0090527)
0.1 4.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.8 4.2 GO:0007386 compartment pattern specification(GO:0007386)
0.2 4.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 4.0 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.5 3.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.7 3.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 3.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
1.1 3.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.5 3.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 3.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 34.8 GO:0043205 fibril(GO:0043205)
0.2 30.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 7.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.3 7.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 4.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 4.6 GO:0042101 T cell receptor complex(GO:0042101)
0.1 4.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 4.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 3.7 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 3.5 GO:0005884 actin filament(GO:0005884)
0.1 3.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 3.2 GO:0055037 recycling endosome(GO:0055037)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.2 2.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 2.0 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.8 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.0 34.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.9 21.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.9 10.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.5 7.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.5 7.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 5.5 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 5.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.5 4.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.4 4.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 4.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 4.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.5 3.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 3.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.4 3.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 3.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 3.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 2.6 GO:0005262 calcium channel activity(GO:0005262)
0.5 2.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 2.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)