Motif ID: Hoxb4

Z-value: 0.411


Transcription factors associated with Hoxb4:

Gene SymbolEntrez IDGene Name
Hoxb4 ENSMUSG00000038692.7 Hoxb4



Activity profile for motif Hoxb4.

activity profile for motif Hoxb4


Sorted Z-values histogram for motif Hoxb4

Sorted Z-values for motif Hoxb4



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_143933204 3.938 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chrX_-_143933089 3.221 ENSMUST00000087313.3
 Dcx
doublecortin
chr12_+_58211772 1.836 ENSMUST00000110671.2
ENSMUST00000044299.2
 Sstr1

somatostatin receptor 1

chr1_-_52490736 1.672 ENSMUST00000170269.1
 Nab1
Ngfi-A binding protein 1
chr2_-_84775388 1.473 ENSMUST00000023994.3
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84775420 1.284 ENSMUST00000111641.1
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr19_+_4711153 1.282 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr8_+_25808474 1.229 ENSMUST00000033979.4
 Star
steroidogenic acute regulatory protein
chr11_+_85353156 1.223 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
 Bcas3





breast carcinoma amplified sequence 3





chr17_+_43952999 1.220 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chrX_+_166344692 1.163 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr12_-_15816762 1.041 ENSMUST00000020922.7
 Trib2
tribbles homolog 2 (Drosophila)
chr8_+_83666827 0.926 ENSMUST00000019608.5
 Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr16_+_78930940 0.902 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr3_-_54714353 0.842 ENSMUST00000178832.1
 Gm21958
predicted gene, 21958
chr4_+_43493345 0.804 ENSMUST00000030181.5
ENSMUST00000107922.2
 Ccdc107

coiled-coil domain containing 107

chr16_-_37384915 0.758 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr11_-_40755201 0.738 ENSMUST00000020576.7
 Ccng1
cyclin G1
chr3_-_37125943 0.730 ENSMUST00000029275.5
 Il2
interleukin 2
chr10_-_92162753 0.730 ENSMUST00000182197.1
 Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr4_-_35845204 0.646 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr7_+_28693032 0.634 ENSMUST00000151227.1
ENSMUST00000108281.1
 Fbxo27

F-box protein 27

chr5_+_143363890 0.608 ENSMUST00000010969.8
 Grid2ip
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
chr1_+_159737510 0.572 ENSMUST00000111669.3
 Tnr
tenascin R
chr16_-_37384940 0.493 ENSMUST00000114781.1
ENSMUST00000114780.1
 Stxbp5l

syntaxin binding protein 5-like

chr10_-_89621253 0.427 ENSMUST00000020102.7
 Slc17a8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr6_+_142413441 0.412 ENSMUST00000088263.4
 B230216G23Rik
RIKEN cDNA B230216G23 gene
chr16_-_94370450 0.368 ENSMUST00000138514.1
 Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_-_30232186 0.368 ENSMUST00000006254.5
 Tbcb
tubulin folding cofactor B
chr9_-_60649793 0.337 ENSMUST00000053171.7
 Lrrc49
leucine rich repeat containing 49
chr14_+_58070547 0.288 ENSMUST00000165526.1
 Fgf9
fibroblast growth factor 9
chr13_+_94083490 0.278 ENSMUST00000156071.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr10_-_59616667 0.172 ENSMUST00000020312.6
 Mcu
mitochondrial calcium uniporter
chr2_-_119156824 0.044 ENSMUST00000135419.1
ENSMUST00000129351.1
ENSMUST00000139519.1
ENSMUST00000094695.5
 Rmdn3



regulator of microtubule dynamics 3



chr7_+_30232310 0.007 ENSMUST00000108193.1
ENSMUST00000108192.1
 Polr2i

polymerase (RNA) II (DNA directed) polypeptide I


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.4 7.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 0.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 0.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 1.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 1.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 3.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 1.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 1.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 1.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 1.7 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 1.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.4 GO:0015813 L-glutamate transport(GO:0015813)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0008091 spectrin(GO:0008091)
0.2 0.6 GO:0072534 perineuronal net(GO:0072534)
0.1 0.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 1.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.3 GO:0031201 SNARE complex(GO:0031201)
0.0 7.0 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 1.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 7.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 0.9 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.2 1.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 2.8 GO:0001848 complement binding(GO:0001848)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 1.0 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.3 GO:0019905 syntaxin binding(GO:0019905)