Motif ID: Hoxb5

Z-value: 0.887


Transcription factors associated with Hoxb5:

Gene SymbolEntrez IDGene Name
Hoxb5 ENSMUSG00000038700.3 Hoxb5



Activity profile for motif Hoxb5.

activity profile for motif Hoxb5


Sorted Z-values histogram for motif Hoxb5

Sorted Z-values for motif Hoxb5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 101 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_18514802 12.122 ENSMUST00000090601.5
 Cttnbp2
cortactin binding protein 2
chr17_-_57087729 11.626 ENSMUST00000071135.5
 Tubb4a
tubulin, beta 4A class IVA
chr1_-_56971762 10.006 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chrX_-_165327376 9.220 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chr12_-_78980758 8.163 ENSMUST00000174072.1
 Tmem229b
transmembrane protein 229B
chr13_+_88821472 7.761 ENSMUST00000118731.1
ENSMUST00000081769.6
 Edil3

EGF-like repeats and discoidin I-like domains 3

chr12_-_78983476 7.361 ENSMUST00000070174.7
 Tmem229b
transmembrane protein 229B
chr13_+_88821606 7.326 ENSMUST00000043111.6
 Edil3
EGF-like repeats and discoidin I-like domains 3
chr11_+_74619594 6.641 ENSMUST00000100866.2
 E130309D14Rik
RIKEN cDNA E130309D14 gene
chr17_+_35076902 6.540 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr10_-_62143906 6.512 ENSMUST00000141724.1
ENSMUST00000150057.1
 2010107G23Rik

RIKEN cDNA 2010107G23 gene

chr17_+_35077080 5.623 ENSMUST00000172959.1
 Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr2_+_158667119 5.560 ENSMUST00000045503.4
 Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr3_-_85722474 5.288 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr3_-_89160155 4.858 ENSMUST00000029686.3
 Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr2_-_153225396 4.790 ENSMUST00000099194.2
 Tspyl3
TSPY-like 3
chr5_+_117133567 4.585 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
 Taok3


TAO kinase 3


chr10_+_80300997 4.505 ENSMUST00000140828.1
ENSMUST00000138909.1
 Apc2

adenomatosis polyposis coli 2

chr10_-_81014902 4.282 ENSMUST00000126317.1
ENSMUST00000092285.3
ENSMUST00000117805.1
 Gng7


guanine nucleotide binding protein (G protein), gamma 7


chr7_+_3390629 4.218 ENSMUST00000182222.1
 Cacng8
calcium channel, voltage-dependent, gamma subunit 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.4 12.2 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 10.7 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.6 10.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 9.3 GO:0007017 microtubule-based process(GO:0007017)
1.3 9.2 GO:0071361 cellular response to zinc ion(GO:0071294) cellular response to ethanol(GO:0071361)
0.3 6.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
1.4 5.6 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
1.3 5.3 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.3 4.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 4.9 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.2 4.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.4 4.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 4.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 3.8 GO:0010225 response to UV-C(GO:0010225)
0.7 3.6 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 3.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 3.5 GO:0019233 sensory perception of pain(GO:0019233)
0.6 3.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 3.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 11.6 GO:0033269 internode region of axon(GO:0033269)
0.0 10.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 10.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 9.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 8.3 GO:0043204 perikaryon(GO:0043204)
0.1 6.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 5.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 5.2 GO:0043005 neuron projection(GO:0043005)
1.0 4.9 GO:0044316 cone cell pedicle(GO:0044316)
0.0 4.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.4 4.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 4.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 4.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 4.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.5 3.6 GO:0033391 chromatoid body(GO:0033391)
0.1 3.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 3.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.5 GO:0044450 microtubule organizing center part(GO:0044450)
0.1 2.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.1 GO:0005178 integrin binding(GO:0005178)
4.1 12.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.5 12.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 11.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
3.1 9.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.2 6.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 5.6 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.9 5.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.0 4.9 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 4.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 4.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 4.2 GO:0016247 channel regulator activity(GO:0016247)
0.2 3.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 3.6 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 3.5 GO:0042165 neurotransmitter binding(GO:0042165)
0.2 3.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 3.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 2.9 GO:0043022 ribosome binding(GO:0043022)
0.1 2.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)