Motif ID: Hoxb7

Z-value: 4.305


Transcription factors associated with Hoxb7:

Gene SymbolEntrez IDGene Name
Hoxb7 ENSMUSG00000038721.8 Hoxb7



Activity profile for motif Hoxb7.

activity profile for motif Hoxb7


Sorted Z-values histogram for motif Hoxb7

Sorted Z-values for motif Hoxb7



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb7

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_54954728 94.030 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr13_+_83504032 90.929 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr6_-_55681257 90.854 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr1_+_19103022 84.907 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr16_+_7069825 76.972 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_+_177445660 75.718 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr2_+_61804453 73.971 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr3_+_18054258 73.286 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chr6_-_13839916 71.207 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr3_+_55461758 68.737 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr19_+_26605106 68.675 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chrX_-_43167817 65.187 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr12_+_29528382 64.634 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr15_+_21111452 63.707 ENSMUST00000075132.6
Cdh12
cadherin 12
chr5_+_117841839 61.736 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr8_-_109251698 61.010 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr1_-_56969827 60.440 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr4_+_101507947 59.909 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr1_-_56969864 59.327 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr17_+_3397189 58.472 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 417 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.1 297.0 GO:0006376 mRNA splice site selection(GO:0006376)
21.8 196.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
5.7 178.2 GO:0060074 synapse maturation(GO:0060074)
5.5 177.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
2.6 176.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
15.0 164.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
9.5 143.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
14.1 126.5 GO:0071420 cellular response to histamine(GO:0071420)
1.5 121.4 GO:0001578 microtubule bundle formation(GO:0001578)
1.3 119.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
18.8 113.1 GO:0072318 clathrin coat disassembly(GO:0072318)
36.3 108.9 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
8.4 108.9 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
13.5 108.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
21.3 106.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
5.9 106.4 GO:0021860 pyramidal neuron development(GO:0021860)
17.3 104.0 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
1.7 102.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
5.1 101.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
2.1 92.0 GO:0045773 positive regulation of axon extension(GO:0045773)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 157 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 443.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 342.7 GO:0016021 integral component of membrane(GO:0016021)
1.6 340.8 GO:0060076 excitatory synapse(GO:0060076)
10.3 196.1 GO:0071564 npBAF complex(GO:0071564)
0.6 194.3 GO:0016604 nuclear body(GO:0016604)
1.7 171.1 GO:0000118 histone deacetylase complex(GO:0000118)
8.4 168.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
10.1 161.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
3.5 150.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
2.7 136.1 GO:0045171 intercellular bridge(GO:0045171)
0.3 132.7 GO:0005768 endosome(GO:0005768)
8.8 132.3 GO:0031045 dense core granule(GO:0031045)
7.2 129.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 114.0 GO:0005887 integral component of plasma membrane(GO:0005887)
12.4 111.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
3.6 111.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
5.3 105.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
3.2 102.9 GO:0042734 presynaptic membrane(GO:0042734)
8.8 97.3 GO:0043083 synaptic cleft(GO:0043083)
1.9 94.2 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 247 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 246.9 GO:0044822 poly(A) RNA binding(GO:0044822)
7.9 237.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.4 194.9 GO:0005057 receptor signaling protein activity(GO:0005057)
7.7 176.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.0 165.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.7 155.0 GO:0008017 microtubule binding(GO:0008017)
2.8 149.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
8.8 149.0 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
1.3 144.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
4.9 143.1 GO:0001786 phosphatidylserine binding(GO:0001786)
1.7 129.9 GO:0005262 calcium channel activity(GO:0005262)
7.2 129.8 GO:0004890 GABA-A receptor activity(GO:0004890)
14.8 118.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
2.8 116.3 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
17.6 105.7 GO:0070699 type II activin receptor binding(GO:0070699)
6.9 90.1 GO:0004385 guanylate kinase activity(GO:0004385)
3.5 84.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
7.1 78.5 GO:0038191 neuropilin binding(GO:0038191)
7.4 73.8 GO:0031749 D2 dopamine receptor binding(GO:0031749)
2.8 71.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)