Motif ID: Hoxc9

Z-value: 0.626


Transcription factors associated with Hoxc9:

Gene SymbolEntrez IDGene Name
Hoxc9 ENSMUSG00000036139.6 Hoxc9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxc9mm10_v2_chr15_+_102977032_1029770320.152.1e-01Click!


Activity profile for motif Hoxc9.

activity profile for motif Hoxc9


Sorted Z-values histogram for motif Hoxc9

Sorted Z-values for motif Hoxc9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc9

PNG image of the network

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Top targets:


Showing 1 to 20 of 68 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_26516620 4.994 ENSMUST00000132820.1
 Notch1
notch 1
chr4_+_136143497 4.755 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr7_-_116038734 4.627 ENSMUST00000166877.1
 Sox6
SRY-box containing gene 6
chr2_+_70474923 4.230 ENSMUST00000100043.2
 Sp5
trans-acting transcription factor 5
chr9_+_35423582 3.961 ENSMUST00000154652.1
 Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr17_-_49564262 3.536 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr10_-_13324160 3.049 ENSMUST00000105545.4
 Phactr2
phosphatase and actin regulator 2
chr1_-_45503282 2.998 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr2_+_102658640 2.724 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_-_13324250 2.532 ENSMUST00000105543.1
 Phactr2
phosphatase and actin regulator 2
chr2_+_91256144 2.425 ENSMUST00000154959.1
ENSMUST00000059566.4
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chrX_-_141474034 2.408 ENSMUST00000101205.2
 Col4a6
collagen, type IV, alpha 6
chr4_+_144893127 2.286 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr10_+_4710119 2.104 ENSMUST00000105588.1
ENSMUST00000105589.1
 Esr1

estrogen receptor 1 (alpha)

chr13_+_94083490 2.014 ENSMUST00000156071.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr2_+_91255954 1.814 ENSMUST00000134699.1
 Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr17_+_24426676 1.691 ENSMUST00000024946.5
 Eci1
enoyl-Coenzyme A delta isomerase 1
chr4_+_107830958 1.631 ENSMUST00000106731.2
 Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr8_-_120228221 1.566 ENSMUST00000183235.1
 A330074K22Rik
RIKEN cDNA A330074K22 gene
chr16_-_37384915 1.564 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 5.0 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
0.2 4.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.4 4.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 4.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 4.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.5 4.0 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
1.0 3.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 2.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 2.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.5 2.5 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.2 2.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 2.3 GO:0042572 retinol metabolic process(GO:0042572)
0.5 2.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 1.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.8 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 1.7 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.4 1.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.4 1.2 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 1.1 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 5.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 4.2 GO:0005802 trans-Golgi network(GO:0005802)
1.0 3.0 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.7 GO:0030673 axolemma(GO:0030673)
0.0 2.6 GO:0031201 SNARE complex(GO:0031201)
0.2 2.5 GO:0005915 zonula adherens(GO:0005915)
0.5 2.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.7 GO:0016607 nuclear speck(GO:0016607)
0.4 1.2 GO:0071914 prominosome(GO:0071914)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.4 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.0 GO:0005112 Notch binding(GO:0005112)
0.1 4.8 GO:0005504 fatty acid binding(GO:0005504)
0.3 4.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 3.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.7 2.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 2.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.5 GO:0019903 protein phosphatase binding(GO:0019903)
0.3 2.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.7 2.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.3 1.7 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.4 1.6 GO:0038025 reelin receptor activity(GO:0038025)
0.3 1.3 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 1.2 GO:0042805 actinin binding(GO:0042805)
0.1 0.6 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)