Motif ID: Hoxd1

Z-value: 0.597


Transcription factors associated with Hoxd1:

Gene SymbolEntrez IDGene Name
Hoxd1 ENSMUSG00000042448.4 Hoxd1



Activity profile for motif Hoxd1.

activity profile for motif Hoxd1


Sorted Z-values histogram for motif Hoxd1

Sorted Z-values for motif Hoxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd1

PNG image of the network

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Top targets:


Showing 1 to 20 of 156 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_156392829 5.533 ENSMUST00000088578.2
 2900097C17Rik
RIKEN cDNA 2900097C17 gene
chrX_-_143933089 4.322 ENSMUST00000087313.3
 Dcx
doublecortin
chrX_-_143933204 4.073 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr10_-_110000219 3.559 ENSMUST00000032719.7
 Nav3
neuron navigator 3
chr9_-_55919605 3.262 ENSMUST00000037408.8
 Scaper
S phase cyclin A-associated protein in the ER
chr1_-_158356258 3.039 ENSMUST00000004133.8
 Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chrM_+_10167 2.995 ENSMUST00000082414.1
 mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr5_+_107497762 2.922 ENSMUST00000152474.1
ENSMUST00000060553.7
 A830010M20Rik

RIKEN cDNA A830010M20 gene

chr2_-_20943413 2.897 ENSMUST00000140230.1
 Arhgap21
Rho GTPase activating protein 21
chr3_-_85722474 2.859 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr13_+_83732438 2.783 ENSMUST00000182701.1
 C130071C03Rik
RIKEN cDNA C130071C03 gene
chr12_+_52699297 2.664 ENSMUST00000095737.3
 Akap6
A kinase (PRKA) anchor protein 6
chr17_-_45659312 2.544 ENSMUST00000120717.1
 Capn11
calpain 11
chr2_+_116067213 2.528 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr5_+_107497718 2.526 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene
chr2_+_170731807 2.509 ENSMUST00000029075.4
 Dok5
docking protein 5
chr12_-_24493656 2.475 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr2_+_37516618 2.401 ENSMUST00000065441.6
 Gpr21
G protein-coupled receptor 21
chr2_-_116067391 2.189 ENSMUST00000140185.1
 2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr16_+_11406618 2.172 ENSMUST00000122168.1
 Snx29
sorting nexin 29

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 8.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 3.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 3.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.6 2.9 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 2.9 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.7 2.7 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.6 2.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 2.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.4 2.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.8 2.3 GO:0019085 early viral transcription(GO:0019085)
0.3 2.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 2.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.7 2.0 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 1.8 GO:0032288 myelin assembly(GO:0032288)
0.0 1.8 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 1.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.4 1.5 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.3 1.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 1.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.5 GO:0030425 dendrite(GO:0030425)
0.0 4.0 GO:0070469 respiratory chain(GO:0070469)
0.1 2.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 2.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 1.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)
0.1 0.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 5.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.9 GO:0005096 GTPase activator activity(GO:0005096)
0.3 2.7 GO:0043495 protein anchor(GO:0043495)
0.1 2.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.8 2.4 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 2.3 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 2.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.2 2.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 2.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 2.1 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.3 2.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 1.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.8 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.4 1.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)