Motif ID: Hsf2
Z-value: 2.246
Transcription factors associated with Hsf2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hsf2 | ENSMUSG00000019878.7 | Hsf2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hsf2 | mm10_v2_chr10_+_57486354_57486414 | -0.37 | 1.4e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.0 | 40.2 | GO:2000974 | negative regulation of pro-B cell differentiation(GO:2000974) |
| 8.9 | 8.9 | GO:2000981 | negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981) |
| 6.1 | 18.4 | GO:0021759 | globus pallidus development(GO:0021759) |
| 6.1 | 24.5 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 5.7 | 17.2 | GO:0030421 | defecation(GO:0030421) |
| 4.7 | 23.4 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 4.7 | 14.0 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
| 4.5 | 13.4 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 4.3 | 13.0 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 3.8 | 60.9 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 3.6 | 18.0 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 3.6 | 14.4 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
| 3.4 | 10.3 | GO:1900275 | negative regulation of phospholipase C activity(GO:1900275) |
| 3.4 | 23.8 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 3.3 | 9.9 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
| 3.2 | 3.2 | GO:0043465 | regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003) |
| 3.1 | 9.4 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
| 3.1 | 21.5 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 3.0 | 12.0 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 3.0 | 23.9 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 2.8 | 8.3 | GO:0003360 | brainstem development(GO:0003360) |
| 2.8 | 8.3 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 2.6 | 10.6 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282) |
| 2.6 | 10.4 | GO:0060032 | notochord regression(GO:0060032) |
| 2.5 | 10.0 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 2.5 | 12.5 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 2.4 | 36.1 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 2.4 | 7.2 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 2.4 | 21.3 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 2.2 | 13.1 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 2.1 | 10.7 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 2.1 | 8.6 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 2.1 | 6.4 | GO:0045819 | positive regulation of glycogen catabolic process(GO:0045819) |
| 2.0 | 6.1 | GO:0097461 | ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) |
| 2.0 | 11.9 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 2.0 | 9.8 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 1.9 | 17.3 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
| 1.9 | 7.4 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) negative regulation of prostatic bud formation(GO:0060686) |
| 1.8 | 7.3 | GO:0045343 | MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) |
| 1.8 | 5.5 | GO:1990046 | positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046) |
| 1.8 | 5.4 | GO:2000564 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
| 1.8 | 14.4 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 1.7 | 10.4 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
| 1.7 | 6.8 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
| 1.7 | 8.4 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 1.7 | 15.1 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 1.7 | 8.4 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 1.6 | 21.0 | GO:0046643 | regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643) |
| 1.6 | 30.2 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 1.5 | 21.4 | GO:0030238 | male sex determination(GO:0030238) |
| 1.5 | 6.1 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 1.5 | 5.9 | GO:0006203 | dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061) |
| 1.5 | 30.7 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 1.4 | 7.2 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 1.4 | 14.4 | GO:1902913 | positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913) |
| 1.3 | 3.9 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
| 1.3 | 5.0 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 1.2 | 13.6 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 1.2 | 3.7 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
| 1.2 | 15.7 | GO:0018126 | protein hydroxylation(GO:0018126) |
| 1.2 | 4.8 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 1.2 | 14.3 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 1.2 | 8.3 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 1.1 | 5.6 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 1.1 | 8.9 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
| 1.1 | 5.5 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
| 1.1 | 3.3 | GO:0019043 | establishment of viral latency(GO:0019043) |
| 1.1 | 7.6 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 1.1 | 5.4 | GO:0003420 | regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) |
| 1.0 | 8.2 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
| 1.0 | 3.9 | GO:0033580 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
| 1.0 | 11.6 | GO:0015825 | L-serine transport(GO:0015825) |
| 1.0 | 2.9 | GO:1903054 | lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334) |
| 1.0 | 6.7 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.9 | 14.8 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.9 | 25.0 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.9 | 12.0 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.9 | 2.7 | GO:0097278 | complement-dependent cytotoxicity(GO:0097278) |
| 0.9 | 2.6 | GO:0040009 | nucleolus to nucleoplasm transport(GO:0032066) regulation of growth rate(GO:0040009) |
| 0.8 | 3.4 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.8 | 10.1 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.8 | 5.0 | GO:0035743 | CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745) |
| 0.8 | 2.5 | GO:1904154 | protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 0.8 | 13.9 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.8 | 1.6 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.8 | 2.4 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.8 | 5.5 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.8 | 14.9 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.8 | 19.4 | GO:0042474 | middle ear morphogenesis(GO:0042474) |
| 0.8 | 6.2 | GO:0006004 | fucose metabolic process(GO:0006004) |
| 0.8 | 6.9 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.7 | 3.6 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) |
| 0.7 | 4.0 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.7 | 11.1 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
| 0.6 | 4.5 | GO:0051084 | 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084) |
| 0.6 | 6.2 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.6 | 9.3 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 0.6 | 2.4 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.6 | 11.5 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.6 | 12.7 | GO:0046596 | regulation of viral entry into host cell(GO:0046596) |
| 0.6 | 7.7 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.6 | 2.3 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.6 | 1.7 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 0.6 | 5.7 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
| 0.6 | 2.3 | GO:0060021 | palate development(GO:0060021) |
| 0.6 | 4.0 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.6 | 6.7 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.6 | 5.6 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.6 | 1.7 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.6 | 2.8 | GO:0072488 | nitrogen utilization(GO:0019740) ammonium transmembrane transport(GO:0072488) |
| 0.5 | 2.7 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
| 0.5 | 1.6 | GO:1905050 | positive regulation of metalloendopeptidase activity(GO:1904685) positive regulation of metallopeptidase activity(GO:1905050) |
| 0.5 | 11.5 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.5 | 27.4 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
| 0.5 | 3.6 | GO:0032782 | bile acid secretion(GO:0032782) |
| 0.5 | 1.5 | GO:0018008 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) |
| 0.5 | 2.5 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.5 | 2.0 | GO:2000587 | regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 0.5 | 2.8 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.4 | 4.0 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.4 | 23.7 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.4 | 1.3 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.4 | 4.9 | GO:0046349 | amino sugar biosynthetic process(GO:0046349) |
| 0.4 | 1.3 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.4 | 1.7 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.4 | 0.8 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) regulation of vascular smooth muscle cell differentiation(GO:1905063) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
| 0.4 | 3.6 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.4 | 2.8 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.4 | 10.2 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.4 | 2.7 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.4 | 5.2 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.4 | 1.4 | GO:2000195 | negative regulation of female gonad development(GO:2000195) |
| 0.4 | 2.9 | GO:0048311 | mitochondrion distribution(GO:0048311) |
| 0.4 | 3.5 | GO:0032048 | cardiolipin metabolic process(GO:0032048) |
| 0.3 | 1.7 | GO:0060018 | astrocyte fate commitment(GO:0060018) |
| 0.3 | 1.7 | GO:0019249 | lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) |
| 0.3 | 4.6 | GO:0042182 | ketone catabolic process(GO:0042182) |
| 0.3 | 4.5 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.3 | 11.3 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
| 0.3 | 6.5 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.3 | 1.8 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.3 | 18.3 | GO:0050728 | negative regulation of inflammatory response(GO:0050728) |
| 0.3 | 1.8 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.3 | 4.2 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.3 | 4.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.3 | 3.5 | GO:0001916 | positive regulation of T cell mediated cytotoxicity(GO:0001916) |
| 0.3 | 6.7 | GO:0000154 | rRNA modification(GO:0000154) |
| 0.3 | 3.8 | GO:0035751 | regulation of lysosomal lumen pH(GO:0035751) |
| 0.3 | 11.5 | GO:0006801 | superoxide metabolic process(GO:0006801) |
| 0.3 | 4.0 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 0.3 | 27.9 | GO:0050772 | positive regulation of axonogenesis(GO:0050772) |
| 0.3 | 9.2 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.3 | 1.4 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.3 | 5.1 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.3 | 13.9 | GO:0002066 | columnar/cuboidal epithelial cell development(GO:0002066) |
| 0.3 | 13.3 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.3 | 2.5 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.3 | 3.1 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.3 | 1.4 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.3 | 2.9 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.3 | 3.4 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.3 | 5.4 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
| 0.3 | 1.3 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.2 | 1.7 | GO:0033280 | response to vitamin D(GO:0033280) |
| 0.2 | 4.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.2 | 4.8 | GO:0033622 | integrin activation(GO:0033622) |
| 0.2 | 4.0 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.2 | 0.7 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.2 | 9.5 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.2 | 3.0 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
| 0.2 | 0.9 | GO:0060353 | regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.2 | 1.8 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.2 | 2.3 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
| 0.2 | 10.9 | GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway(GO:2001238) |
| 0.2 | 7.5 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.2 | 4.9 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.2 | 4.2 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.2 | 2.2 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.2 | 2.6 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.2 | 2.0 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.2 | 6.5 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
| 0.2 | 3.5 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.2 | 2.0 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.2 | 2.1 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
| 0.2 | 3.3 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.2 | 4.7 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
| 0.2 | 0.3 | GO:0001803 | antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
| 0.2 | 10.7 | GO:0007127 | meiosis I(GO:0007127) |
| 0.2 | 2.2 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
| 0.2 | 1.1 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.1 | 1.1 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.1 | 0.3 | GO:0033146 | regulation of intracellular estrogen receptor signaling pathway(GO:0033146) |
| 0.1 | 1.9 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.1 | 1.4 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.1 | 1.2 | GO:0002176 | male germ cell proliferation(GO:0002176) |
| 0.1 | 11.2 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.1 | 3.7 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.1 | 2.5 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 2.2 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
| 0.1 | 5.6 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 1.1 | GO:1990173 | regulation of establishment of protein localization to telomere(GO:0070203) protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
| 0.1 | 2.1 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.1 | 2.8 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 1.0 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
| 0.1 | 14.3 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.1 | 4.8 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.1 | 7.4 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.1 | 4.1 | GO:0048636 | positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863) |
| 0.1 | 1.3 | GO:0007249 | I-kappaB kinase/NF-kappaB signaling(GO:0007249) |
| 0.1 | 2.6 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.1 | 0.8 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
| 0.1 | 0.5 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 0.1 | 2.8 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.1 | 0.3 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.1 | 0.4 | GO:0060838 | lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
| 0.1 | 6.2 | GO:0007601 | visual perception(GO:0007601) |
| 0.1 | 0.4 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
| 0.1 | 3.4 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.1 | 7.4 | GO:0060348 | bone development(GO:0060348) |
| 0.1 | 4.7 | GO:0006513 | protein monoubiquitination(GO:0006513) |
| 0.1 | 0.1 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.1 | 0.9 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) negative regulation of cysteine-type endopeptidase activity(GO:2000117) |
| 0.1 | 0.3 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.1 | 7.8 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
| 0.1 | 1.5 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 3.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.1 | 5.5 | GO:0007517 | muscle organ development(GO:0007517) |
| 0.1 | 3.5 | GO:0032200 | telomere maintenance(GO:0000723) telomere organization(GO:0032200) |
| 0.1 | 0.3 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.1 | 3.2 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.0 | 4.8 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 1.5 | GO:0009225 | nucleotide-sugar metabolic process(GO:0009225) |
| 0.0 | 1.1 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.0 | 1.4 | GO:0017145 | stem cell division(GO:0017145) |
| 0.0 | 0.2 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of receptor catabolic process(GO:2000645) |
| 0.0 | 0.4 | GO:0006532 | aspartate biosynthetic process(GO:0006532) |
| 0.0 | 1.8 | GO:0009411 | response to UV(GO:0009411) |
| 0.0 | 5.7 | GO:0006869 | lipid transport(GO:0006869) |
| 0.0 | 1.0 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
| 0.0 | 7.2 | GO:0006631 | fatty acid metabolic process(GO:0006631) |
| 0.0 | 2.7 | GO:0051099 | positive regulation of binding(GO:0051099) |
| 0.0 | 0.4 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
| 0.0 | 0.4 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.4 | GO:0033137 | negative regulation of peptidyl-serine phosphorylation(GO:0033137) |
| 0.0 | 0.4 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 0.0 | 0.6 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 2.1 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 2.0 | GO:0050796 | regulation of insulin secretion(GO:0050796) |
| 0.0 | 0.8 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
| 0.0 | 4.8 | GO:0032259 | methylation(GO:0032259) |
| 0.0 | 0.1 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.4 | GO:0006220 | pyrimidine nucleotide metabolic process(GO:0006220) |
| 0.0 | 6.4 | GO:0055114 | oxidation-reduction process(GO:0055114) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.9 | 23.8 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
| 3.5 | 10.6 | GO:0042585 | germinal vesicle(GO:0042585) |
| 3.3 | 26.3 | GO:0005818 | aster(GO:0005818) |
| 2.8 | 8.3 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 2.7 | 13.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 2.5 | 15.1 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
| 2.4 | 7.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 2.3 | 11.7 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 2.3 | 7.0 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 2.2 | 2.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 1.9 | 28.6 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 1.7 | 8.7 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 1.6 | 8.2 | GO:0031523 | Myb complex(GO:0031523) |
| 1.6 | 6.2 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
| 1.5 | 12.3 | GO:0032420 | stereocilium(GO:0032420) |
| 1.2 | 6.2 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 1.2 | 13.0 | GO:0031091 | platelet alpha granule(GO:0031091) extrinsic component of external side of plasma membrane(GO:0031232) |
| 1.1 | 11.5 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 1.0 | 3.0 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 1.0 | 7.6 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.9 | 3.5 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825) |
| 0.8 | 9.2 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.8 | 5.9 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.8 | 12.0 | GO:0045180 | basal cortex(GO:0045180) |
| 0.8 | 10.8 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.7 | 34.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.7 | 2.9 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.7 | 7.1 | GO:0000243 | commitment complex(GO:0000243) |
| 0.7 | 5.4 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.7 | 10.0 | GO:0043205 | fibril(GO:0043205) |
| 0.7 | 8.5 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.6 | 2.6 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.6 | 9.5 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.6 | 1.8 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.6 | 2.8 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.6 | 5.6 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.5 | 8.6 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.5 | 2.6 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.5 | 34.1 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.5 | 2.5 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.5 | 14.0 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.4 | 19.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.4 | 23.0 | GO:0016459 | myosin complex(GO:0016459) |
| 0.4 | 25.4 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.4 | 33.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.4 | 5.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.3 | 2.3 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.3 | 6.7 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.3 | 2.5 | GO:0098536 | deuterosome(GO:0098536) |
| 0.3 | 1.8 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.3 | 16.9 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.3 | 3.1 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.3 | 20.2 | GO:0030315 | T-tubule(GO:0030315) |
| 0.3 | 6.1 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.3 | 4.7 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.3 | 8.7 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.2 | 17.0 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.2 | 2.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.2 | 2.6 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.2 | 1.2 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.2 | 11.9 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.2 | 3.0 | GO:0031512 | motile primary cilium(GO:0031512) |
| 0.2 | 2.1 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.2 | 3.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.2 | 10.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 5.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.2 | 20.8 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.2 | 12.0 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.2 | 1.6 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.2 | 0.6 | GO:0071014 | U2-type post-mRNA release spliceosomal complex(GO:0071008) post-mRNA release spliceosomal complex(GO:0071014) |
| 0.2 | 2.5 | GO:0032039 | integrator complex(GO:0032039) |
| 0.2 | 33.7 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.2 | 1.9 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.2 | 2.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 3.9 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.2 | 1.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.2 | 3.9 | GO:0002102 | podosome(GO:0002102) |
| 0.2 | 0.3 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.2 | 3.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 5.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 1.6 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 21.5 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 1.0 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.1 | 13.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 11.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 4.8 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 39.0 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 1.9 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 2.1 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.1 | 2.0 | GO:0001741 | XY body(GO:0001741) |
| 0.1 | 4.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 1.7 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.1 | 10.7 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.1 | 1.3 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 0.5 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 1.0 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 4.9 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.1 | 1.1 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.1 | 3.1 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 8.7 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.1 | 1.0 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 1.4 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 0.1 | 2.4 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 0.3 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.1 | 10.6 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 13.2 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 3.5 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 3.3 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 0.9 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 2.5 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.0 | 2.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.9 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 6.1 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 1.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 2.8 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 1.3 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.2 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 3.5 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 3.3 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 5.6 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 2.9 | GO:0031968 | organelle outer membrane(GO:0031968) |
| 0.0 | 1.2 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.1 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 0.0 | 0.5 | GO:0015934 | large ribosomal subunit(GO:0015934) cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.4 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 1.7 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.0 | 14.2 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.0 | 1.4 | GO:0016324 | apical plasma membrane(GO:0016324) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.0 | 18.0 | GO:0005534 | galactose binding(GO:0005534) |
| 5.3 | 26.3 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 4.9 | 14.7 | GO:0005118 | sevenless binding(GO:0005118) |
| 3.9 | 15.7 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 3.3 | 13.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
| 3.0 | 23.8 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 2.9 | 11.5 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 2.8 | 8.4 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 2.8 | 11.1 | GO:2001069 | glycogen binding(GO:2001069) |
| 2.8 | 60.9 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 2.7 | 21.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 2.6 | 10.6 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 2.5 | 9.8 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 2.4 | 9.6 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
| 2.4 | 11.9 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 2.3 | 6.8 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 2.2 | 6.5 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 2.1 | 6.4 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 2.1 | 8.2 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 2.0 | 6.1 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 2.0 | 30.7 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 2.0 | 10.0 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 2.0 | 19.7 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 1.8 | 5.5 | GO:1901611 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
| 1.8 | 5.3 | GO:0005110 | frizzled-2 binding(GO:0005110) |
| 1.8 | 7.1 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 1.7 | 8.4 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 1.7 | 8.4 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 1.7 | 13.4 | GO:0031432 | titin binding(GO:0031432) |
| 1.6 | 4.8 | GO:0032052 | bile acid binding(GO:0032052) |
| 1.5 | 4.6 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 1.5 | 6.2 | GO:0042806 | fucose binding(GO:0042806) |
| 1.5 | 18.4 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 1.5 | 10.6 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 1.5 | 7.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 1.4 | 9.9 | GO:0043559 | insulin binding(GO:0043559) |
| 1.4 | 8.4 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 1.4 | 8.3 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 1.4 | 15.1 | GO:0034943 | acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409) |
| 1.3 | 12.1 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 1.3 | 8.9 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 1.2 | 3.7 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
| 1.2 | 13.3 | GO:0016151 | nickel cation binding(GO:0016151) |
| 1.2 | 8.3 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 1.1 | 25.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 1.0 | 14.7 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 1.0 | 18.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 1.0 | 4.0 | GO:0042731 | PH domain binding(GO:0042731) |
| 1.0 | 5.9 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 1.0 | 5.9 | GO:0002135 | CTP binding(GO:0002135) |
| 1.0 | 21.3 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 1.0 | 2.9 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
| 1.0 | 21.9 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.9 | 14.8 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.9 | 4.5 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
| 0.9 | 14.0 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.9 | 13.1 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.9 | 10.3 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.8 | 0.8 | GO:0030284 | estrogen receptor activity(GO:0030284) |
| 0.8 | 5.9 | GO:0032554 | purine deoxyribonucleotide binding(GO:0032554) |
| 0.8 | 3.4 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.8 | 23.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.8 | 4.1 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.8 | 8.9 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.8 | 2.4 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.8 | 5.6 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.8 | 12.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.8 | 4.6 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.8 | 34.9 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.8 | 7.6 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.7 | 3.0 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.7 | 12.5 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.7 | 8.7 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.7 | 4.2 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.7 | 7.6 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.7 | 5.4 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.7 | 2.0 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153) |
| 0.7 | 14.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.7 | 3.9 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
| 0.6 | 5.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.6 | 5.7 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.6 | 4.0 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.5 | 2.2 | GO:0003941 | L-serine ammonia-lyase activity(GO:0003941) |
| 0.5 | 2.6 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.5 | 4.7 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.5 | 4.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.5 | 2.6 | GO:0051880 | Y-form DNA binding(GO:0000403) bubble DNA binding(GO:0000405) G-quadruplex DNA binding(GO:0051880) |
| 0.5 | 2.6 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 0.5 | 14.8 | GO:0005112 | Notch binding(GO:0005112) |
| 0.5 | 1.5 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 0.5 | 1.5 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) |
| 0.5 | 22.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.5 | 3.0 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.5 | 8.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.5 | 4.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.5 | 3.2 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.5 | 20.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.5 | 3.2 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.4 | 10.8 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.4 | 2.2 | GO:0051022 | Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.4 | 2.2 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.4 | 16.8 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.4 | 2.6 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.4 | 7.2 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.4 | 1.7 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.4 | 6.2 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.4 | 4.7 | GO:0034946 | 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466) |
| 0.4 | 5.0 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.4 | 1.2 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.4 | 2.7 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.4 | 1.9 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.4 | 11.7 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.4 | 10.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.4 | 13.6 | GO:0070888 | E-box binding(GO:0070888) |
| 0.4 | 4.2 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.3 | 5.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.3 | 3.1 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.3 | 4.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.3 | 4.4 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.3 | 7.0 | GO:0030291 | protein serine/threonine kinase inhibitor activity(GO:0030291) |
| 0.3 | 86.0 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.3 | 14.1 | GO:0001012 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012) |
| 0.3 | 2.8 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.3 | 8.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.3 | 3.8 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.3 | 4.4 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.3 | 1.4 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.3 | 9.7 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.3 | 4.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.3 | 26.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.2 | 5.7 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.2 | 2.8 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.2 | 7.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.2 | 13.1 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.2 | 2.6 | GO:0016208 | AMP binding(GO:0016208) |
| 0.2 | 2.2 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.2 | 1.6 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.2 | 12.5 | GO:0019955 | cytokine binding(GO:0019955) |
| 0.2 | 2.4 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.2 | 7.1 | GO:0017069 | snRNA binding(GO:0017069) |
| 0.2 | 6.6 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.2 | 1.5 | GO:0046790 | virion binding(GO:0046790) |
| 0.2 | 0.9 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.2 | 15.7 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.2 | 9.3 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.2 | 3.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.2 | 2.8 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.2 | 3.2 | GO:0016859 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859) |
| 0.2 | 2.0 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.2 | 3.3 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.2 | 1.7 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.1 | 0.4 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.1 | 2.2 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
| 0.1 | 1.0 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 3.0 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 0.5 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.1 | 5.1 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 18.8 | GO:0008237 | metallopeptidase activity(GO:0008237) |
| 0.1 | 0.8 | GO:0031386 | protein tag(GO:0031386) |
| 0.1 | 0.6 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.1 | 3.6 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.1 | 0.4 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.1 | 2.6 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.1 | 12.8 | GO:0003774 | motor activity(GO:0003774) |
| 0.1 | 2.2 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.1 | 0.3 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.1 | 1.2 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 2.6 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 2.0 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 6.1 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.1 | 0.4 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
| 0.1 | 12.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.1 | 7.1 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.1 | 0.4 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.1 | 1.9 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.1 | 2.3 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 1.8 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 1.8 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 2.1 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 1.7 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 1.0 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 8.2 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 1.8 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 1.1 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 6.7 | GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity(GO:0008757) |
| 0.0 | 0.7 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 0.0 | 3.7 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
| 0.0 | 7.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 1.5 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 1.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.7 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.3 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 0.0 | 1.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 1.0 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.4 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.0 | 0.5 | GO:0034945 | dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-palmitoyltransferase activity(GO:0016416) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595) |
| 0.0 | 0.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.2 | GO:0050253 | prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
| 0.0 | 1.5 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.1 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
