Motif ID: Hsf4
Z-value: 0.755
Transcription factors associated with Hsf4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hsf4 | ENSMUSG00000033249.4 | Hsf4 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.4 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 1.1 | 5.4 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 0.9 | 2.7 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.9 | 5.2 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
| 0.5 | 2.3 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.4 | 1.6 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 0.4 | 1.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.4 | 2.7 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
| 0.4 | 1.5 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 0.4 | 1.5 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 0.4 | 1.4 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.3 | 1.0 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
| 0.3 | 1.4 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.3 | 1.1 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
| 0.3 | 0.8 | GO:0019043 | establishment of viral latency(GO:0019043) |
| 0.3 | 0.5 | GO:0035771 | interleukin-4-mediated signaling pathway(GO:0035771) |
| 0.3 | 0.8 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
| 0.3 | 0.8 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.2 | 1.0 | GO:0002606 | positive regulation of dendritic cell antigen processing and presentation(GO:0002606) |
| 0.2 | 1.0 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.2 | 1.2 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 0.2 | 0.7 | GO:0031117 | serotonin receptor signaling pathway(GO:0007210) positive regulation of microtubule depolymerization(GO:0031117) |
| 0.2 | 1.7 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.2 | 0.6 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.2 | 0.6 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
| 0.2 | 0.6 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
| 0.2 | 0.5 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.2 | 1.1 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.2 | 0.7 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.2 | 0.5 | GO:0008228 | opsonization(GO:0008228) |
| 0.2 | 0.5 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 0.2 | 0.3 | GO:0001803 | antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
| 0.2 | 1.3 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.2 | 1.3 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.2 | 1.1 | GO:0015862 | uridine transport(GO:0015862) |
| 0.2 | 0.6 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.1 | 0.5 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.1 | 0.5 | GO:0072061 | inner medullary collecting duct development(GO:0072061) |
| 0.1 | 1.0 | GO:1990173 | protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
| 0.1 | 0.4 | GO:1904154 | protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 0.1 | 0.6 | GO:0031033 | myosin filament organization(GO:0031033) |
| 0.1 | 0.7 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
| 0.1 | 0.9 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.1 | 0.3 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
| 0.1 | 0.6 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.1 | 0.7 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.1 | 1.1 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
| 0.1 | 3.5 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
| 0.1 | 0.6 | GO:0097460 | ferrous iron import into cell(GO:0097460) |
| 0.1 | 0.3 | GO:0034145 | positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
| 0.1 | 0.4 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.1 | 0.8 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.1 | 1.1 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
| 0.1 | 0.4 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
| 0.1 | 0.6 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.1 | 0.4 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.1 | 0.7 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.1 | 1.2 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.1 | 0.3 | GO:1903265 | keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.1 | 0.3 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.1 | 0.1 | GO:0018307 | enzyme active site formation(GO:0018307) |
| 0.1 | 0.6 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.1 | 0.7 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
| 0.1 | 0.6 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 0.1 | 0.5 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.1 | 0.4 | GO:0019695 | choline metabolic process(GO:0019695) |
| 0.1 | 0.7 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.1 | 0.3 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.1 | 1.2 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 0.1 | 0.3 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.1 | 0.8 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.1 | 1.1 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.1 | 0.2 | GO:0032627 | interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) |
| 0.1 | 0.7 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.1 | 0.8 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.1 | 0.3 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.1 | 0.2 | GO:0016598 | protein arginylation(GO:0016598) |
| 0.1 | 0.3 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.1 | 1.1 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.3 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.0 | 1.2 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.0 | 0.9 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.5 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.1 | GO:1903054 | lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334) |
| 0.0 | 0.3 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.0 | 2.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.5 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.0 | 0.2 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.0 | 1.1 | GO:0010043 | response to zinc ion(GO:0010043) |
| 0.0 | 0.4 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.0 | 0.8 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.0 | 0.6 | GO:0033599 | regulation of mammary gland epithelial cell proliferation(GO:0033599) |
| 0.0 | 0.2 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.0 | 0.4 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.0 | 0.6 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.0 | 0.1 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
| 0.0 | 0.4 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 0.2 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.0 | 0.1 | GO:0072592 | oxygen metabolic process(GO:0072592) |
| 0.0 | 0.2 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.0 | 0.3 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.0 | 0.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.5 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) axonemal dynein complex assembly(GO:0070286) |
| 0.0 | 0.2 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.0 | 0.1 | GO:1902605 | heterotrimeric G-protein complex assembly(GO:1902605) |
| 0.0 | 1.0 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.0 | 0.2 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
| 0.0 | 0.8 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.2 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.0 | 0.1 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.0 | 0.3 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.0 | 0.2 | GO:0051036 | regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.0 | 1.2 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.0 | 0.1 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.0 | 0.6 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 0.4 | GO:0001553 | luteinization(GO:0001553) |
| 0.0 | 0.4 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.0 | 0.1 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.0 | 0.2 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 0.0 | 1.6 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 1.1 | GO:0015992 | proton transport(GO:0015992) |
| 0.0 | 0.7 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.3 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.0 | 0.6 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.1 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.0 | 0.2 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.3 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.0 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
| 0.0 | 0.2 | GO:0035337 | fatty-acyl-CoA metabolic process(GO:0035337) |
| 0.0 | 0.2 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.0 | 0.3 | GO:0070232 | regulation of T cell apoptotic process(GO:0070232) |
| 0.0 | 0.3 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.0 | 1.0 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
| 0.0 | 0.1 | GO:0007602 | phototransduction(GO:0007602) |
| 0.0 | 0.3 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
| 0.0 | 0.1 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 5.2 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
| 0.6 | 1.8 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.3 | 3.5 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.2 | 3.0 | GO:0046930 | pore complex(GO:0046930) |
| 0.2 | 0.9 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.2 | 2.1 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.2 | 0.5 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.1 | 2.7 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 1.0 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.7 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.1 | 1.1 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 0.8 | GO:0033503 | HULC complex(GO:0033503) |
| 0.1 | 0.6 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.1 | 0.4 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 0.8 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.1 | 0.6 | GO:0097433 | dense body(GO:0097433) HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 1.1 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 0.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 0.8 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 0.9 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 0.5 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 0.4 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.1 | 0.3 | GO:0000938 | GARP complex(GO:0000938) |
| 0.1 | 0.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.0 | 0.7 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.1 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.0 | 0.8 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.3 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.0 | 0.9 | GO:0036379 | myofilament(GO:0036379) |
| 0.0 | 1.5 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 3.0 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.3 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 3.5 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.2 | GO:0060091 | kinocilium(GO:0060091) |
| 0.0 | 1.1 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 1.1 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.3 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.2 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.0 | 0.3 | GO:0044447 | axoneme part(GO:0044447) |
| 0.0 | 1.2 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 2.2 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 1.4 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.1 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.1 | GO:0097361 | CIA complex(GO:0097361) |
| 0.0 | 0.2 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 2.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 2.1 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.5 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.4 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.4 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 0.4 | GO:0005840 | ribosome(GO:0005840) |
| 0.0 | 0.1 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.1 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.0 | 0.6 | GO:0045335 | phagocytic vesicle(GO:0045335) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 5.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.7 | 4.5 | GO:0002135 | CTP binding(GO:0002135) |
| 0.5 | 1.4 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.5 | 2.7 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.4 | 1.3 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) |
| 0.3 | 1.3 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
| 0.3 | 2.1 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.3 | 0.8 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.2 | 3.5 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.2 | 1.0 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.2 | 1.0 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.2 | 0.7 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.2 | 0.6 | GO:0005118 | sevenless binding(GO:0005118) |
| 0.2 | 0.7 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589) |
| 0.2 | 0.7 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.2 | 0.9 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.2 | 0.3 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.2 | 0.6 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.2 | 1.1 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.1 | 0.4 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.1 | 1.5 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.1 | 2.0 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 1.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 1.0 | GO:0023026 | MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026) |
| 0.1 | 1.5 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.3 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
| 0.1 | 0.8 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 0.3 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 0.1 | 1.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 0.3 | GO:0034618 | arginine binding(GO:0034618) |
| 0.1 | 1.1 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 0.6 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.1 | 1.2 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.1 | 0.2 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 0.6 | GO:0043559 | insulin binding(GO:0043559) |
| 0.1 | 0.4 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
| 0.1 | 0.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 0.5 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.1 | 0.5 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) alpha-D-galactofuranose transporter activity(GO:0103116) |
| 0.1 | 1.1 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.1 | 0.2 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 0.1 | 1.1 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 0.2 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.1 | 0.2 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.1 | 0.4 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
| 0.1 | 1.1 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 0.3 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.0 | 0.3 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.0 | 1.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.5 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.4 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.2 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.0 | 0.5 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 0.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.0 | 0.4 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 2.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.3 | GO:0052872 | 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014) |
| 0.0 | 0.5 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 0.1 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.0 | 0.8 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 0.0 | 0.2 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.0 | 2.2 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.7 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.4 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 1.2 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.2 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.0 | 0.3 | GO:0008193 | tRNA guanylyltransferase activity(GO:0008193) |
| 0.0 | 0.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 0.3 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.0 | 1.2 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.4 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.6 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
| 0.0 | 0.1 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 0.0 | 1.1 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) procollagen-proline dioxygenase activity(GO:0019798) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
| 0.0 | 0.7 | GO:0030291 | protein serine/threonine kinase inhibitor activity(GO:0030291) |
| 0.0 | 3.6 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 3.9 | GO:1901681 | sulfur compound binding(GO:1901681) |
| 0.0 | 1.4 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 0.2 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.0 | 0.1 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.0 | 0.2 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.0 | 0.1 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.0 | 0.5 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.8 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.2 | GO:0016229 | retinol dehydrogenase activity(GO:0004745) steroid dehydrogenase activity(GO:0016229) |
| 0.0 | 0.1 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.0 | 0.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.1 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.0 | 0.0 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
| 0.0 | 0.2 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.0 | 0.5 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.8 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 0.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.7 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.0 | 0.1 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.1 | GO:0008758 | thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606) |
| 0.0 | 0.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 1.1 | GO:0005267 | potassium channel activity(GO:0005267) |
| 0.0 | 0.1 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.0 | 0.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 0.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.1 | GO:0015168 | glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254) urea channel activity(GO:0015265) |
