Motif ID: Hsf4

Z-value: 0.755


Transcription factors associated with Hsf4:

Gene SymbolEntrez IDGene Name
Hsf4 ENSMUSG00000033249.4 Hsf4



Activity profile for motif Hsf4.

activity profile for motif Hsf4


Sorted Z-values histogram for motif Hsf4

Sorted Z-values for motif Hsf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_46566432 3.461 ENSMUST00000030021.7
ENSMUST00000107757.1
 Coro2a

coronin, actin binding protein 2A

chr1_+_194938821 3.381 ENSMUST00000016638.2
ENSMUST00000110815.2
 Cd34

CD34 antigen

chr15_-_66801577 3.024 ENSMUST00000168589.1
 Sla
src-like adaptor
chr9_+_71215779 2.745 ENSMUST00000034723.5
 Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr4_-_136892867 2.679 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr17_-_50094277 2.332 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr6_-_136941887 2.177 ENSMUST00000111891.1
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr7_-_110862944 1.746 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr12_-_110696289 1.705 ENSMUST00000021698.6
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr6_-_136941494 1.651 ENSMUST00000111892.1
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr8_-_71537402 1.639 ENSMUST00000051672.7
 Bst2
bone marrow stromal cell antigen 2
chr1_+_195017399 1.582 ENSMUST00000181273.1
 A330023F24Rik
RIKEN cDNA A330023F24 gene
chr6_-_136941694 1.525 ENSMUST00000032344.5
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr4_+_152178126 1.491 ENSMUST00000075363.3
 Acot7
acyl-CoA thioesterase 7
chr16_+_23107413 1.434 ENSMUST00000023599.6
ENSMUST00000168891.1
 Eif4a2

eukaryotic translation initiation factor 4A2

chr19_+_47854970 1.414 ENSMUST00000026050.7
 Gsto1
glutathione S-transferase omega 1
chr12_-_110696332 1.331 ENSMUST00000094361.4
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr2_+_130405256 1.240 ENSMUST00000110281.1
ENSMUST00000028898.3
 1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr2_-_64975762 1.223 ENSMUST00000156765.1
 Grb14
growth factor receptor bound protein 14
chr14_+_34375504 1.182 ENSMUST00000111908.1
 Mmrn2
multimerin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 136 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 5.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.9 5.2 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 3.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
1.1 3.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.9 2.7 GO:0035799 ureter maturation(GO:0035799)
0.4 2.7 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.5 2.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 2.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 1.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.4 1.6 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.0 1.6 GO:0007601 visual perception(GO:0007601)
0.4 1.5 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.4 1.5 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.4 1.4 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.3 1.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 1.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 1.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.4 1.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 1.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 1.2 GO:0016926 protein desumoylation(GO:0016926)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 5.2 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.3 3.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 3.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 3.0 GO:0046930 pore complex(GO:0046930)
0.0 3.0 GO:0072562 blood microparticle(GO:0072562)
0.1 2.7 GO:0042588 zymogen granule(GO:0042588)
0.0 2.2 GO:0005604 basement membrane(GO:0005604)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 2.1 GO:0030018 Z disc(GO:0030018)
0.6 1.8 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 5.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7 4.5 GO:0002135 CTP binding(GO:0002135)
0.0 3.9 GO:1901681 sulfur compound binding(GO:1901681)
0.0 3.6 GO:0051015 actin filament binding(GO:0051015)
0.2 3.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.5 2.7 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 2.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.3 2.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 2.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 1.4 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 1.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.4 1.3 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.3 1.3 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 1.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)