Motif ID: Hsfy2

Z-value: 1.204


Transcription factors associated with Hsfy2:

Gene SymbolEntrez IDGene Name
Hsfy2 ENSMUSG00000045336.4 Hsfy2



Activity profile for motif Hsfy2.

activity profile for motif Hsfy2


Sorted Z-values histogram for motif Hsfy2

Sorted Z-values for motif Hsfy2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsfy2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_152847993 19.852 ENSMUST00000028969.8
 Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr2_+_152847961 17.547 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
 Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr14_-_67715585 17.205 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
 Cdca2


cell division cycle associated 2


chr11_-_102925086 14.105 ENSMUST00000021311.9
 Kif18b
kinesin family member 18B
chr13_+_51645232 13.943 ENSMUST00000075853.5
 Cks2
CDC28 protein kinase regulatory subunit 2
chr4_+_105157339 12.014 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chr17_-_25797032 11.681 ENSMUST00000165838.1
ENSMUST00000002344.6
 Metrn

meteorin, glial cell differentiation regulator

chr1_+_139454747 11.674 ENSMUST00000053364.8
ENSMUST00000097554.3
 Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr1_+_74391479 11.032 ENSMUST00000027367.7
 Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr13_-_64153194 10.183 ENSMUST00000059817.4
ENSMUST00000117241.1
 Zfp367

zinc finger protein 367

chr8_-_53638945 9.871 ENSMUST00000047768.4
 Neil3
nei like 3 (E. coli)
chr10_+_20347788 9.860 ENSMUST00000169712.1
 Mtfr2
mitochondrial fission regulator 2
chr2_+_70562007 9.174 ENSMUST00000094934.4
 Gad1
glutamate decarboxylase 1
chr9_-_64172879 9.148 ENSMUST00000176299.1
ENSMUST00000130127.1
ENSMUST00000176794.1
ENSMUST00000177045.1
 Zwilch



zwilch kinetochore protein



chr1_+_44551483 8.378 ENSMUST00000074525.3
 Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr17_+_50698525 8.091 ENSMUST00000061681.7
 Gm7334
predicted gene 7334
chr8_-_22185758 7.664 ENSMUST00000046916.7
 Ckap2
cytoskeleton associated protein 2
chr9_-_72491939 7.399 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
 Tex9




testis expressed gene 9




chr2_+_25180737 7.210 ENSMUST00000104999.2
 Nrarp
Notch-regulated ankyrin repeat protein
chr2_+_131234043 7.091 ENSMUST00000041362.5
ENSMUST00000110199.2
 Mavs

mitochondrial antiviral signaling protein


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 166 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 42.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.4 25.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.3 17.2 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 13.8 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 13.7 GO:0008380 RNA splicing(GO:0008380)
0.3 12.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 11.0 GO:0007127 meiosis I(GO:0007127)
1.4 10.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.1 10.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 9.9 GO:0006284 base-excision repair(GO:0006284)
0.9 9.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.3 9.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 8.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.2 8.5 GO:0000266 mitochondrial fission(GO:0000266)
0.1 8.0 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
2.6 7.7 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.4 7.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.4 7.5 GO:0003334 keratinocyte development(GO:0003334)
0.7 7.2 GO:0014807 regulation of somitogenesis(GO:0014807)
2.4 7.1 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.4 51.5 GO:0005818 aster(GO:0005818)
0.0 36.2 GO:0005654 nucleoplasm(GO:0005654)
0.0 20.9 GO:0005615 extracellular space(GO:0005615)
2.3 11.7 GO:0036449 microtubule minus-end(GO:0036449)
0.8 10.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 10.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 9.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 9.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
3.0 9.1 GO:1990423 RZZ complex(GO:1990423)
0.0 9.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 8.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 8.1 GO:0060077 inhibitory synapse(GO:0060077)
1.5 7.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 7.6 GO:0005657 replication fork(GO:0005657)
0.1 7.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 7.1 GO:0000922 spindle pole(GO:0000922)
0.6 6.7 GO:0005916 fascia adherens(GO:0005916)
0.1 6.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 5.9 GO:0031526 brush border membrane(GO:0031526)
0.2 5.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.5 37.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.9 14.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 13.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 12.1 GO:0005516 calmodulin binding(GO:0005516)
1.2 11.0 GO:0008420 CTD phosphatase activity(GO:0008420)
1.8 10.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.9 10.2 GO:0045294 alpha-catenin binding(GO:0045294)
2.0 9.9 GO:0000405 bubble DNA binding(GO:0000405)
1.1 9.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.3 9.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 8.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 8.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 7.8 GO:0008017 microtubule binding(GO:0008017)
0.0 7.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 7.5 GO:0005509 calcium ion binding(GO:0005509)
0.1 7.2 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
1.8 7.1 GO:0050700 CARD domain binding(GO:0050700)
0.2 6.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
2.0 6.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 6.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)