Motif ID: Id4

Z-value: 0.906


Transcription factors associated with Id4:

Gene SymbolEntrez IDGene Name
Id4 ENSMUSG00000021379.1 Id4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Id4mm10_v2_chr13_+_48261427_482614270.235.9e-02Click!


Activity profile for motif Id4.

activity profile for motif Id4


Sorted Z-values histogram for motif Id4

Sorted Z-values for motif Id4



Network of associatons between targets according to the STRING database.



First level regulatory network of Id4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_103843685 7.809 ENSMUST00000172237.1
 Ednrb
endothelin receptor type B
chr16_+_91269759 7.614 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr1_-_164458345 7.404 ENSMUST00000027863.7
 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_-_122611238 7.324 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr19_+_36409719 6.300 ENSMUST00000062389.5
 Pcgf5
polycomb group ring finger 5
chr14_-_103844173 5.753 ENSMUST00000022718.3
 Ednrb
endothelin receptor type B
chr3_+_145758674 5.703 ENSMUST00000029845.8
 Ddah1
dimethylarginine dimethylaminohydrolase 1
chr17_-_25570678 5.625 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr11_+_3488275 5.591 ENSMUST00000064265.6
 Pla2g3
phospholipase A2, group III
chr11_+_115163333 5.551 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr19_-_42202150 5.547 ENSMUST00000018966.7
 Sfrp5
secreted frizzled-related sequence protein 5
chr14_+_54936456 5.395 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr3_+_89436699 5.279 ENSMUST00000038942.3
ENSMUST00000130858.1
 Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr6_+_17307632 5.228 ENSMUST00000115453.1
 Cav1
caveolin 1, caveolae protein
chr3_+_89436736 5.188 ENSMUST00000146630.1
ENSMUST00000145753.1
 Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr1_+_86045863 4.949 ENSMUST00000165824.1
 2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr19_-_36736653 4.871 ENSMUST00000087321.2
 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chrX_+_100730178 4.824 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr6_+_17307272 4.816 ENSMUST00000115454.1
 Cav1
caveolin 1, caveolae protein
chr14_+_27039001 4.776 ENSMUST00000035336.3
 Il17rd
interleukin 17 receptor D

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 332 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.1 12.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
2.4 12.2 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
2.9 11.4 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
1.3 8.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 8.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
1.9 7.6 GO:0060032 notochord regression(GO:0060032)
2.4 7.3 GO:0006601 creatine biosynthetic process(GO:0006601)
1.2 7.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 7.3 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.3 7.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.3 6.9 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.6 6.5 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
1.5 6.0 GO:0019372 lipoxygenase pathway(GO:0019372)
1.2 5.9 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.6 5.7 GO:0000052 citrulline metabolic process(GO:0000052)
1.9 5.6 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
1.8 5.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
1.8 5.3 GO:0072034 renal vesicle induction(GO:0072034)
0.2 5.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.0 5.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 23.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 18.3 GO:0005730 nucleolus(GO:0005730)
0.1 17.0 GO:0031965 nuclear membrane(GO:0031965)
0.8 12.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.6 11.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 8.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 8.6 GO:0031012 extracellular matrix(GO:0031012)
0.5 8.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.6 7.6 GO:0097542 ciliary tip(GO:0097542)
0.1 7.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 6.9 GO:0090544 BAF-type complex(GO:0090544)
1.1 6.5 GO:0016011 dystroglycan complex(GO:0016011)
1.1 5.6 GO:0032426 stereocilium tip(GO:0032426)
0.6 5.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 5.1 GO:0001741 XY body(GO:0001741)
1.0 5.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5 4.9 GO:0042587 glycogen granule(GO:0042587)
0.4 4.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 4.9 GO:0031519 PcG protein complex(GO:0031519)
0.1 4.7 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 232 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 16.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
4.5 13.6 GO:0004962 endothelin receptor activity(GO:0004962)
2.4 12.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.1 11.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.6 8.9 GO:0051393 alpha-actinin binding(GO:0051393)
1.3 8.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 8.4 GO:0051015 actin filament binding(GO:0051015)
2.0 8.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 6.8 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 6.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 6.2 GO:0005096 GTPase activator activity(GO:0005096)
0.1 6.1 GO:0008201 heparin binding(GO:0008201)
0.6 5.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 5.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.5 5.4 GO:0070097 delta-catenin binding(GO:0070097)
0.6 5.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 5.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 4.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 4.8 GO:0015108 chloride transmembrane transporter activity(GO:0015108)
0.8 4.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)