Motif ID: Insm1

Z-value: 0.664


Transcription factors associated with Insm1:

Gene SymbolEntrez IDGene Name
Insm1 ENSMUSG00000068154.4 Insm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Insm1mm10_v2_chr2_+_146221921_1462219210.714.2e-12Click!


Activity profile for motif Insm1.

activity profile for motif Insm1


Sorted Z-values histogram for motif Insm1

Sorted Z-values for motif Insm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Insm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 131 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_55116935 9.409 ENSMUST00000022819.5
 Jph4
junctophilin 4
chr3_+_156561792 7.999 ENSMUST00000074015.4
 Negr1
neuronal growth regulator 1
chr3_+_156562141 6.919 ENSMUST00000175773.1
 Negr1
neuronal growth regulator 1
chr3_+_156561950 6.725 ENSMUST00000041425.5
ENSMUST00000106065.1
 Negr1

neuronal growth regulator 1

chrX_+_9199865 6.670 ENSMUST00000069763.2
 Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr12_+_95692212 6.634 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr12_+_102948843 6.135 ENSMUST00000101099.5
 Unc79
unc-79 homolog (C. elegans)
chr3_-_73056943 5.632 ENSMUST00000059407.7
 Slitrk3
SLIT and NTRK-like family, member 3
chr16_-_45724600 5.621 ENSMUST00000096057.4
 Tagln3
transgelin 3
chr2_+_178141920 5.470 ENSMUST00000103066.3
 Phactr3
phosphatase and actin regulator 3
chr2_+_28205648 5.290 ENSMUST00000102879.3
ENSMUST00000028177.4
 Olfm1

olfactomedin 1

chr4_-_88033328 4.912 ENSMUST00000078090.5
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr16_-_67620880 4.806 ENSMUST00000114292.1
ENSMUST00000120898.1
 Cadm2

cell adhesion molecule 2

chr12_-_86884808 4.365 ENSMUST00000038422.6
 Irf2bpl
interferon regulatory factor 2 binding protein-like
chr5_-_137741102 4.303 ENSMUST00000149512.1
 Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr5_+_111417263 4.206 ENSMUST00000094463.4
 Mn1
meningioma 1
chr7_+_4690760 4.013 ENSMUST00000048248.7
 Brsk1
BR serine/threonine kinase 1
chr5_-_137741601 3.770 ENSMUST00000119498.1
ENSMUST00000061789.7
 Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr16_-_67620805 3.756 ENSMUST00000120594.1
 Cadm2
cell adhesion molecule 2
chr6_-_85069449 3.397 ENSMUST00000160783.1
ENSMUST00000160197.1
 Exoc6b

exocyst complex component 6B


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 21.7 GO:0007631 feeding behavior(GO:0007631)
0.1 9.4 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.2 8.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 8.1 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
2.6 7.9 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.2 7.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.6 6.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 5.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 5.3 GO:0023041 neuronal signal transduction(GO:0023041)
1.7 5.1 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.5 4.9 GO:0007379 segment specification(GO:0007379)
0.8 4.8 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.6 4.5 GO:0005513 detection of calcium ion(GO:0005513)
0.4 4.4 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.6 4.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 3.9 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 3.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 3.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 3.1 GO:0060041 retina development in camera-type eye(GO:0060041)
0.6 3.0 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 17.3 GO:0031225 anchored component of membrane(GO:0031225)
1.9 9.4 GO:0030314 junctional membrane complex(GO:0030314)
0.2 8.6 GO:0032809 neuronal cell body membrane(GO:0032809)
2.6 7.9 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 7.4 GO:0008021 synaptic vesicle(GO:0008021)
0.1 7.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 5.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.0 5.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 5.1 GO:0005911 cell-cell junction(GO:0005911)
0.1 4.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.9 GO:0000922 spindle pole(GO:0000922)
0.2 3.4 GO:0000145 exocyst(GO:0000145)
1.0 3.0 GO:0043512 inhibin A complex(GO:0043512)
0.0 2.8 GO:0098793 presynapse(GO:0098793)
0.0 2.7 GO:0043204 perikaryon(GO:0043204)
0.0 2.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.2 2.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.8 GO:0032279 asymmetric synapse(GO:0032279)
0.3 1.6 GO:0033010 paranodal junction(GO:0033010)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 10.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.6 7.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.4 7.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 6.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 5.9 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 5.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 4.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 4.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 3.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 3.4 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.3 3.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.5 3.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 2.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 2.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 2.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 2.0 GO:0051434 BH3 domain binding(GO:0051434)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)