Motif ID: Irf2_Irf1_Irf8_Irf9_Irf7
Z-value: 3.320
Transcription factors associated with Irf2_Irf1_Irf8_Irf9_Irf7:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Irf1 | ENSMUSG00000018899.10 | Irf1 |
| Irf2 | ENSMUSG00000031627.7 | Irf2 |
| Irf7 | ENSMUSG00000025498.8 | Irf7 |
| Irf8 | ENSMUSG00000041515.3 | Irf8 |
| Irf9 | ENSMUSG00000002325.8 | Irf9 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Irf1 | mm10_v2_chr11_+_53770458_53770509 | 0.60 | 3.0e-08 | Click! |
| Irf8 | mm10_v2_chr8_+_120736352_120736385 | 0.46 | 7.3e-05 | Click! |
| Irf2 | mm10_v2_chr8_+_46739745_46739791 | 0.39 | 7.9e-04 | Click! |
| Irf9 | mm10_v2_chr14_+_55604550_55604579 | -0.31 | 8.4e-03 | Click! |
| Irf7 | mm10_v2_chr7_-_141266415_141266481 | -0.24 | 4.8e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.1 | 39.4 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
| 5.9 | 29.6 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 4.8 | 33.6 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
| 4.2 | 21.2 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 4.1 | 12.4 | GO:0006059 | hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401) |
| 4.1 | 12.3 | GO:0045404 | positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 3.6 | 18.1 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 3.6 | 14.4 | GO:1902990 | mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
| 3.3 | 10.0 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 3.2 | 9.5 | GO:0060364 | frontal suture morphogenesis(GO:0060364) |
| 3.2 | 25.4 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 2.8 | 16.9 | GO:0010528 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
| 2.6 | 26.2 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 2.4 | 28.5 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 2.4 | 7.1 | GO:0038145 | macrophage colony-stimulating factor signaling pathway(GO:0038145) |
| 2.3 | 11.6 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 2.2 | 4.5 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) |
| 2.1 | 15.1 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 2.1 | 6.4 | GO:0050713 | negative regulation of interleukin-1 beta secretion(GO:0050713) |
| 2.1 | 12.9 | GO:0032488 | Cdc42 protein signal transduction(GO:0032488) |
| 2.0 | 5.9 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 1.9 | 7.7 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 1.9 | 3.7 | GO:0043696 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
| 1.9 | 13.0 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
| 1.8 | 7.2 | GO:1903416 | negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416) |
| 1.7 | 8.6 | GO:0030091 | protein repair(GO:0030091) |
| 1.7 | 13.7 | GO:1900225 | NLRP3 inflammasome complex assembly(GO:0044546) regulation of NLRP3 inflammasome complex assembly(GO:1900225) |
| 1.6 | 4.9 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
| 1.6 | 11.1 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 1.5 | 7.7 | GO:2000668 | dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) |
| 1.5 | 7.5 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 1.5 | 6.0 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994) |
| 1.5 | 4.4 | GO:1990481 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481) |
| 1.5 | 7.3 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
| 1.5 | 4.4 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
| 1.4 | 10.1 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 1.4 | 5.8 | GO:0003360 | brainstem development(GO:0003360) |
| 1.4 | 1.4 | GO:0045349 | interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) |
| 1.4 | 4.3 | GO:0015889 | cobalamin transport(GO:0015889) |
| 1.4 | 4.3 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 1.4 | 19.8 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 1.4 | 4.2 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 1.3 | 19.9 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 1.3 | 9.2 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 1.2 | 3.7 | GO:0014891 | striated muscle atrophy(GO:0014891) |
| 1.2 | 3.7 | GO:0015960 | diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
| 1.2 | 4.9 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 1.2 | 3.6 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 1.2 | 3.6 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
| 1.2 | 3.5 | GO:0090289 | regulation of osteoclast proliferation(GO:0090289) |
| 1.2 | 4.6 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 1.1 | 6.8 | GO:0003383 | apical constriction(GO:0003383) |
| 1.1 | 4.4 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
| 1.1 | 3.2 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 1.1 | 9.6 | GO:0085020 | protein K6-linked ubiquitination(GO:0085020) |
| 1.1 | 4.3 | GO:0071449 | cellular response to lipid hydroperoxide(GO:0071449) |
| 1.0 | 5.0 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 1.0 | 10.8 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 1.0 | 2.9 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 0.9 | 4.7 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
| 0.9 | 4.6 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
| 0.9 | 2.7 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
| 0.9 | 1.8 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
| 0.9 | 2.7 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
| 0.9 | 3.6 | GO:0009597 | detection of virus(GO:0009597) |
| 0.8 | 5.8 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.8 | 2.5 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.8 | 18.8 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.8 | 6.5 | GO:2000781 | positive regulation of double-strand break repair(GO:2000781) |
| 0.8 | 3.2 | GO:1903463 | mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463) |
| 0.8 | 3.2 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 0.8 | 8.0 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.8 | 4.0 | GO:0070460 | thyroid-stimulating hormone secretion(GO:0070460) |
| 0.8 | 1.6 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.8 | 6.3 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.8 | 3.1 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.8 | 3.1 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.8 | 2.3 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
| 0.7 | 3.0 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.7 | 2.9 | GO:0032901 | positive regulation of neurotrophin production(GO:0032901) |
| 0.7 | 2.8 | GO:0048143 | astrocyte activation(GO:0048143) ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.7 | 2.1 | GO:0019441 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
| 0.7 | 2.1 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.7 | 7.5 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.7 | 2.0 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.7 | 3.3 | GO:0015867 | ATP transport(GO:0015867) |
| 0.6 | 1.9 | GO:0019478 | D-amino acid catabolic process(GO:0019478) |
| 0.6 | 1.9 | GO:0070844 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.6 | 12.4 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.6 | 4.3 | GO:0042095 | interferon-gamma biosynthetic process(GO:0042095) |
| 0.6 | 3.7 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.6 | 4.8 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.6 | 2.4 | GO:0072602 | interleukin-4 secretion(GO:0072602) |
| 0.6 | 5.2 | GO:1901970 | positive regulation of mitotic sister chromatid separation(GO:1901970) |
| 0.6 | 4.0 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.6 | 4.0 | GO:0060700 | regulation of ribonuclease activity(GO:0060700) |
| 0.6 | 10.8 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.6 | 1.7 | GO:0070172 | oculomotor nerve development(GO:0021557) positive regulation of tooth mineralization(GO:0070172) |
| 0.6 | 1.1 | GO:0039530 | MDA-5 signaling pathway(GO:0039530) |
| 0.6 | 1.7 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.5 | 8.0 | GO:0036065 | fucosylation(GO:0036065) |
| 0.5 | 3.7 | GO:1904667 | negative regulation of ubiquitin protein ligase activity(GO:1904667) |
| 0.5 | 1.1 | GO:0090202 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 0.5 | 2.1 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.5 | 1.6 | GO:1902071 | regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
| 0.5 | 1.5 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.5 | 2.0 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
| 0.5 | 4.0 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.5 | 1.9 | GO:0035934 | corticosterone secretion(GO:0035934) |
| 0.5 | 3.4 | GO:0015840 | urea transport(GO:0015840) urea transmembrane transport(GO:0071918) |
| 0.5 | 2.9 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.5 | 8.7 | GO:0051127 | positive regulation of actin nucleation(GO:0051127) |
| 0.5 | 1.4 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 0.5 | 1.4 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.5 | 6.0 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.5 | 8.7 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.5 | 2.7 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.5 | 2.7 | GO:0048852 | diencephalon morphogenesis(GO:0048852) |
| 0.4 | 1.8 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.4 | 13.0 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
| 0.4 | 1.3 | GO:0090272 | negative regulation of fibroblast growth factor production(GO:0090272) |
| 0.4 | 3.0 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.4 | 0.8 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 0.4 | 4.4 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.4 | 5.7 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.4 | 2.7 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.4 | 1.1 | GO:0070269 | pyroptosis(GO:0070269) |
| 0.4 | 2.6 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
| 0.4 | 1.1 | GO:1903351 | regulation of protein autoubiquitination(GO:1902498) response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
| 0.4 | 1.5 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
| 0.4 | 1.8 | GO:0035989 | tendon development(GO:0035989) |
| 0.4 | 1.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.3 | 6.6 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.3 | 1.0 | GO:0007210 | serotonin receptor signaling pathway(GO:0007210) |
| 0.3 | 1.0 | GO:0045113 | integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) |
| 0.3 | 3.7 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.3 | 3.3 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
| 0.3 | 2.3 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
| 0.3 | 1.0 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 0.3 | 2.6 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.3 | 16.2 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.3 | 2.2 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
| 0.3 | 2.4 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.3 | 3.0 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.3 | 0.9 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 0.3 | 0.9 | GO:0042275 | error-free postreplication DNA repair(GO:0042275) |
| 0.3 | 2.4 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.3 | 2.6 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.3 | 12.3 | GO:0010390 | histone monoubiquitination(GO:0010390) |
| 0.3 | 0.9 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.3 | 0.6 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.3 | 0.9 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.3 | 0.3 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.3 | 1.4 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
| 0.3 | 1.1 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.3 | 1.9 | GO:0051984 | positive regulation of chromosome segregation(GO:0051984) |
| 0.3 | 9.6 | GO:0035082 | axoneme assembly(GO:0035082) |
| 0.3 | 1.1 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.3 | 8.9 | GO:0071346 | cellular response to interferon-gamma(GO:0071346) |
| 0.3 | 1.3 | GO:0046654 | 'de novo' IMP biosynthetic process(GO:0006189) tetrahydrofolate biosynthetic process(GO:0046654) |
| 0.3 | 3.6 | GO:1904293 | negative regulation of ERAD pathway(GO:1904293) |
| 0.3 | 1.3 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
| 0.3 | 1.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.3 | 1.5 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.3 | 5.8 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
| 0.2 | 0.7 | GO:0033030 | negative regulation of neutrophil apoptotic process(GO:0033030) |
| 0.2 | 1.5 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.2 | 2.7 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.2 | 1.9 | GO:0046851 | negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851) |
| 0.2 | 1.7 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.2 | 0.7 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.2 | 23.9 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.2 | 0.9 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.2 | 0.5 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
| 0.2 | 0.7 | GO:0045073 | positive regulation of interleukin-23 production(GO:0032747) chemokine biosynthetic process(GO:0042033) regulation of chemokine biosynthetic process(GO:0045073) positive regulation of chemokine biosynthetic process(GO:0045080) chemokine metabolic process(GO:0050755) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) |
| 0.2 | 6.3 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.2 | 3.4 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.2 | 1.5 | GO:0019240 | citrulline biosynthetic process(GO:0019240) |
| 0.2 | 14.2 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
| 0.2 | 0.6 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.2 | 0.6 | GO:1904749 | regulation of telomeric DNA binding(GO:1904742) regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751) |
| 0.2 | 3.1 | GO:0042407 | cristae formation(GO:0042407) |
| 0.2 | 0.8 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.2 | 1.2 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.2 | 2.1 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
| 0.2 | 6.0 | GO:0048662 | negative regulation of smooth muscle cell proliferation(GO:0048662) |
| 0.2 | 0.6 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
| 0.2 | 4.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.2 | 2.3 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.2 | 0.9 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.2 | 1.3 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.2 | 0.5 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.2 | 0.5 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
| 0.2 | 1.4 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.2 | 0.5 | GO:0042701 | progesterone secretion(GO:0042701) |
| 0.2 | 5.3 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.2 | 5.5 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.2 | 0.2 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.2 | 1.0 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) paranodal junction assembly(GO:0030913) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503) |
| 0.2 | 3.8 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.2 | 0.7 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.2 | 2.5 | GO:0019430 | removal of superoxide radicals(GO:0019430) |
| 0.2 | 1.9 | GO:0072010 | renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
| 0.2 | 2.2 | GO:0030225 | macrophage differentiation(GO:0030225) |
| 0.2 | 0.8 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.2 | 0.8 | GO:0071169 | establishment of protein localization to chromatin(GO:0071169) |
| 0.2 | 0.9 | GO:0051096 | regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096) |
| 0.2 | 0.6 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
| 0.1 | 10.3 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
| 0.1 | 1.8 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 1.4 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) |
| 0.1 | 1.0 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.1 | 4.1 | GO:0030901 | midbrain development(GO:0030901) |
| 0.1 | 1.2 | GO:0061684 | chaperone-mediated autophagy(GO:0061684) |
| 0.1 | 1.5 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.1 | 2.1 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.1 | 10.4 | GO:0019395 | fatty acid oxidation(GO:0019395) |
| 0.1 | 0.5 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
| 0.1 | 2.2 | GO:0043537 | negative regulation of blood vessel endothelial cell migration(GO:0043537) |
| 0.1 | 3.5 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.1 | 1.5 | GO:0000394 | RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 0.1 | 2.2 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.1 | 1.2 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.1 | 1.3 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.1 | 3.3 | GO:0007094 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 0.1 | 5.4 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.1 | 0.2 | GO:0036151 | negative regulation of cellular amine metabolic process(GO:0033239) phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 0.1 | 0.5 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.1 | 11.9 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.1 | 0.4 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 0.1 | 0.6 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.1 | 1.8 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.1 | 1.5 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 0.4 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.1 | 0.8 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.1 | 0.5 | GO:0032782 | bile acid secretion(GO:0032782) |
| 0.1 | 0.6 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 0.3 | GO:1904469 | positive regulation of tumor necrosis factor secretion(GO:1904469) negative regulation of interleukin-10 secretion(GO:2001180) |
| 0.1 | 15.5 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.1 | 1.1 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.1 | 1.0 | GO:0009062 | fatty acid catabolic process(GO:0009062) |
| 0.1 | 2.3 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.1 | 4.2 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.1 | 0.9 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.1 | 1.9 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 0.6 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 0.6 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 1.8 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 1.8 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.1 | 3.1 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 1.5 | GO:0042987 | amyloid precursor protein catabolic process(GO:0042987) |
| 0.1 | 0.5 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.1 | 0.5 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 1.1 | GO:0045840 | positive regulation of mitotic nuclear division(GO:0045840) |
| 0.1 | 8.7 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.1 | 2.2 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.1 | 1.8 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
| 0.1 | 1.3 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.1 | 5.2 | GO:0060606 | tube closure(GO:0060606) |
| 0.1 | 4.1 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 1.8 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.1 | 2.8 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.1 | 0.4 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.1 | 14.4 | GO:0043010 | camera-type eye development(GO:0043010) |
| 0.1 | 4.4 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.1 | 1.4 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 3.1 | GO:0048709 | oligodendrocyte differentiation(GO:0048709) |
| 0.1 | 0.2 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255) |
| 0.1 | 0.6 | GO:0000271 | polysaccharide biosynthetic process(GO:0000271) |
| 0.1 | 0.5 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
| 0.1 | 2.4 | GO:0007498 | mesoderm development(GO:0007498) |
| 0.1 | 1.3 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 2.8 | GO:0043473 | pigmentation(GO:0043473) |
| 0.1 | 0.9 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.1 | 0.2 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.1 | 1.2 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.0 | 1.4 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 0.3 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.6 | GO:1903427 | negative regulation of reactive oxygen species biosynthetic process(GO:1903427) |
| 0.0 | 0.5 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 3.8 | GO:0048814 | regulation of dendrite morphogenesis(GO:0048814) |
| 0.0 | 2.7 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
| 0.0 | 0.1 | GO:0042196 | dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197) |
| 0.0 | 0.4 | GO:0071384 | cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385) |
| 0.0 | 0.3 | GO:1904587 | glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587) |
| 0.0 | 0.2 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
| 0.0 | 1.0 | GO:0051351 | positive regulation of ligase activity(GO:0051351) |
| 0.0 | 1.5 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.0 | 0.5 | GO:0055070 | copper ion homeostasis(GO:0055070) |
| 0.0 | 0.9 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 0.6 | GO:0030865 | cortical cytoskeleton organization(GO:0030865) |
| 0.0 | 0.5 | GO:0071897 | DNA biosynthetic process(GO:0071897) |
| 0.0 | 1.4 | GO:0006278 | RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004) |
| 0.0 | 0.3 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.0 | 0.4 | GO:0060049 | regulation of protein glycosylation(GO:0060049) |
| 0.0 | 0.2 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.0 | 0.1 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.0 | 0.8 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
| 0.0 | 0.1 | GO:0072092 | renal vesicle formation(GO:0072033) ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093) |
| 0.0 | 0.2 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.0 | 0.9 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 0.4 | GO:0001963 | synaptic transmission, dopaminergic(GO:0001963) |
| 0.0 | 0.2 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 1.1 | GO:0071774 | response to fibroblast growth factor(GO:0071774) |
| 0.0 | 2.0 | GO:0006006 | glucose metabolic process(GO:0006006) |
| 0.0 | 0.0 | GO:0036344 | platelet morphogenesis(GO:0036344) |
| 0.0 | 0.1 | GO:1901162 | serotonin biosynthetic process(GO:0042427) indole-containing compound biosynthetic process(GO:0042435) primary amino compound biosynthetic process(GO:1901162) |
| 0.0 | 0.4 | GO:0051570 | regulation of histone H3-K9 methylation(GO:0051570) |
| 0.0 | 0.4 | GO:0045739 | positive regulation of DNA repair(GO:0045739) |
| 0.0 | 0.0 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 1.2 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
| 0.0 | 0.4 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.0 | 0.0 | GO:0097035 | regulation of membrane lipid distribution(GO:0097035) |
| 0.0 | 0.3 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.0 | 0.0 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
| 0.0 | 0.2 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.0 | 0.5 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
| 0.0 | 1.1 | GO:0006821 | chloride transport(GO:0006821) |
| 0.0 | 0.2 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.2 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.8 | 14.4 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 4.1 | 53.8 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 3.1 | 12.4 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 2.8 | 25.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 2.4 | 7.1 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 2.1 | 18.6 | GO:0030478 | actin cap(GO:0030478) |
| 1.9 | 11.6 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 1.9 | 5.8 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 1.8 | 11.1 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 1.7 | 26.6 | GO:0005614 | interstitial matrix(GO:0005614) |
| 1.6 | 6.4 | GO:0032127 | dense core granule membrane(GO:0032127) |
| 1.5 | 7.7 | GO:0043657 | host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) |
| 1.4 | 4.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 1.4 | 6.8 | GO:1990462 | omegasome(GO:1990462) |
| 1.3 | 14.5 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
| 1.2 | 7.5 | GO:0000796 | condensin complex(GO:0000796) |
| 1.2 | 6.2 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 1.2 | 3.7 | GO:0097447 | dendritic tree(GO:0097447) |
| 1.2 | 17.8 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 1.1 | 10.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 1.1 | 4.4 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
| 1.1 | 6.4 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 1.1 | 8.5 | GO:0001520 | outer dense fiber(GO:0001520) |
| 1.0 | 7.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.9 | 2.8 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.9 | 2.7 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.8 | 6.8 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.8 | 8.2 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.8 | 2.5 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
| 0.7 | 5.9 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.7 | 2.2 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.7 | 2.8 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.7 | 11.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.7 | 2.7 | GO:1990357 | terminal web(GO:1990357) |
| 0.7 | 2.0 | GO:0000814 | ESCRT II complex(GO:0000814) |
| 0.6 | 15.2 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.6 | 3.6 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.6 | 8.2 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.6 | 2.3 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
| 0.5 | 2.6 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.5 | 3.0 | GO:0045179 | apical cortex(GO:0045179) |
| 0.5 | 5.7 | GO:0016589 | NURF complex(GO:0016589) |
| 0.5 | 33.1 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.5 | 1.8 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.4 | 2.2 | GO:0072487 | MSL complex(GO:0072487) |
| 0.4 | 3.0 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.4 | 19.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.4 | 5.7 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.4 | 1.2 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.4 | 5.9 | GO:0042555 | MCM complex(GO:0042555) |
| 0.4 | 3.1 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.4 | 1.1 | GO:0044754 | amphisome(GO:0044753) autolysosome(GO:0044754) |
| 0.4 | 1.5 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.4 | 27.6 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.3 | 5.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.3 | 3.1 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.3 | 32.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.3 | 3.3 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.3 | 3.6 | GO:0031105 | septin complex(GO:0031105) |
| 0.3 | 2.7 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.3 | 3.9 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.3 | 0.9 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.3 | 1.1 | GO:0061702 | inflammasome complex(GO:0061702) |
| 0.3 | 2.3 | GO:0042611 | MHC protein complex(GO:0042611) |
| 0.3 | 1.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.3 | 1.4 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.3 | 1.0 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.2 | 3.1 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.2 | 19.1 | GO:0005604 | basement membrane(GO:0005604) |
| 0.2 | 1.8 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.2 | 1.8 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.2 | 1.6 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.2 | 1.4 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 0.2 | 12.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.2 | 2.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 1.7 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 2.1 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 1.5 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.1 | 4.0 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 1.1 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 4.8 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.1 | 1.5 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.1 | 1.5 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.1 | 1.9 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 1.9 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.1 | 1.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 2.3 | GO:0045120 | pronucleus(GO:0045120) |
| 0.1 | 6.7 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 6.3 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.1 | 0.8 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.1 | 0.4 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 1.1 | GO:0051286 | cell tip(GO:0051286) |
| 0.1 | 3.2 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.1 | 0.9 | GO:0097386 | glial cell projection(GO:0097386) |
| 0.1 | 32.7 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 1.1 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 1.1 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 5.6 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.1 | 2.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 3.2 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 0.8 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.1 | 4.1 | GO:0016234 | inclusion body(GO:0016234) |
| 0.1 | 1.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 8.0 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 0.6 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 4.0 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.1 | 1.0 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.1 | 0.3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.1 | 6.9 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 0.4 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 0.5 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 0.7 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.1 | 4.7 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.1 | 5.7 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.1 | 23.0 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 0.6 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 2.1 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 3.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 5.3 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 1.2 | GO:0000152 | nuclear ubiquitin ligase complex(GO:0000152) |
| 0.1 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.6 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.0 | 0.9 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.0 | 0.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.5 | GO:0001527 | microfibril(GO:0001527) |
| 0.0 | 6.6 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.6 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 0.0 | 0.3 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.2 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.0 | 0.5 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 1.9 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 0.8 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.6 | GO:0030120 | vesicle coat(GO:0030120) |
| 0.0 | 1.3 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 1.2 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 1.3 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.1 | GO:0044452 | nucleolar part(GO:0044452) |
| 0.0 | 0.6 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 2.9 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 0.5 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.2 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 21.4 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.0 | 0.5 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 136.9 | GO:0005575 | cellular_component(GO:0005575) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 26.6 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 5.3 | 21.2 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 4.9 | 14.6 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 4.5 | 17.9 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 4.2 | 16.9 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 2.9 | 11.6 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 2.8 | 8.5 | GO:0070052 | collagen V binding(GO:0070052) |
| 2.6 | 10.4 | GO:0003844 | 1,4-alpha-glucan branching enzyme activity(GO:0003844) |
| 1.7 | 24.4 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 1.7 | 3.4 | GO:0046978 | TAP1 binding(GO:0046978) TAP2 binding(GO:0046979) |
| 1.6 | 6.3 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 1.5 | 4.6 | GO:0071862 | protein phosphatase type 1 activator activity(GO:0071862) |
| 1.4 | 5.8 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 1.4 | 4.3 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
| 1.4 | 11.2 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 1.3 | 7.7 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 1.2 | 8.6 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
| 1.2 | 3.6 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618) |
| 1.1 | 4.5 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
| 1.1 | 1.1 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
| 1.1 | 4.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 1.1 | 1.1 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
| 1.1 | 4.3 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 1.1 | 25.4 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 1.0 | 10.1 | GO:0052872 | 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014) |
| 1.0 | 11.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 1.0 | 6.0 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 1.0 | 3.0 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 1.0 | 4.9 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 1.0 | 8.7 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.9 | 8.2 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.9 | 2.7 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.9 | 3.5 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 0.9 | 4.4 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.9 | 13.7 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.8 | 3.3 | GO:0005347 | ATP transmembrane transporter activity(GO:0005347) |
| 0.8 | 4.6 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.8 | 7.7 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.7 | 30.4 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.7 | 2.2 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
| 0.7 | 2.1 | GO:0048045 | 4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623) |
| 0.7 | 11.9 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.7 | 2.1 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.7 | 2.1 | GO:0005171 | hepatocyte growth factor receptor binding(GO:0005171) |
| 0.7 | 8.2 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.7 | 2.6 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.7 | 2.0 | GO:0009881 | photoreceptor activity(GO:0009881) |
| 0.6 | 1.9 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.6 | 2.5 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.6 | 4.3 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.6 | 1.8 | GO:0005110 | frizzled-2 binding(GO:0005110) |
| 0.6 | 11.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.6 | 3.4 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.6 | 14.6 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.6 | 2.8 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.5 | 3.3 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.5 | 7.0 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.5 | 5.3 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.5 | 3.2 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.5 | 2.6 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.5 | 7.8 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.5 | 1.5 | GO:0004471 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) |
| 0.5 | 2.8 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.5 | 1.9 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.5 | 1.4 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 0.5 | 1.8 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.5 | 12.2 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.4 | 10.3 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.4 | 1.3 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
| 0.4 | 1.3 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.4 | 2.0 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.4 | 8.8 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.4 | 1.9 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 0.4 | 2.9 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.4 | 2.9 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.4 | 1.4 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.4 | 6.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.4 | 6.0 | GO:0001848 | complement binding(GO:0001848) |
| 0.3 | 6.6 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.3 | 9.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.3 | 2.4 | GO:0046790 | virion binding(GO:0046790) |
| 0.3 | 1.0 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.3 | 3.7 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.3 | 1.7 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.3 | 6.8 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.3 | 1.0 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.3 | 5.7 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.3 | 7.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.3 | 8.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.3 | 1.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.3 | 1.2 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
| 0.3 | 1.8 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 0.3 | 0.9 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.3 | 2.4 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
| 0.3 | 9.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.3 | 3.1 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.3 | 6.3 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.3 | 7.2 | GO:0042805 | actinin binding(GO:0042805) |
| 0.3 | 1.1 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.3 | 12.6 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.3 | 1.0 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589) |
| 0.3 | 3.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.2 | 1.5 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.2 | 2.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.2 | 0.9 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.2 | 2.1 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.2 | 3.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 0.9 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.2 | 6.3 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.2 | 0.7 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.2 | 4.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.2 | 4.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 1.2 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.2 | 57.7 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
| 0.2 | 2.3 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.2 | 1.3 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.2 | 0.9 | GO:0043559 | insulin binding(GO:0043559) |
| 0.2 | 1.9 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.2 | 0.8 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.2 | 3.9 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.2 | 2.7 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.2 | 0.9 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.2 | 11.8 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.2 | 2.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 1.5 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
| 0.1 | 2.3 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.1 | 9.9 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.1 | 33.9 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 1.3 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.1 | 2.3 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.1 | 2.8 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
| 0.1 | 2.9 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.1 | 0.6 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
| 0.1 | 1.5 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
| 0.1 | 0.7 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.1 | 7.6 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.1 | 1.1 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.1 | 5.2 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) |
| 0.1 | 1.8 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 0.4 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.1 | 0.7 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.1 | 2.3 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.1 | 0.5 | GO:0015168 | glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254) |
| 0.1 | 2.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 18.8 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 0.2 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.1 | 0.7 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.1 | 3.5 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.1 | 1.0 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
| 0.1 | 3.3 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.1 | 4.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 1.4 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.1 | 9.9 | GO:0001948 | glycoprotein binding(GO:0001948) |
| 0.1 | 3.2 | GO:0030594 | neurotransmitter receptor activity(GO:0030594) |
| 0.1 | 0.2 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 4.7 | GO:0035496 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062) |
| 0.1 | 1.1 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 1.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.1 | 0.6 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.1 | 0.6 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 1.8 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.1 | 0.4 | GO:0043842 | Kdo transferase activity(GO:0043842) |
| 0.1 | 0.2 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.1 | 1.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390) |
| 0.1 | 0.9 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.1 | 1.4 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.1 | 1.8 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.1 | 0.6 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.1 | 1.0 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 0.3 | GO:0033814 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
| 0.1 | 0.8 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 2.3 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 0.5 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 1.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 10.8 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.1 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
| 0.0 | 18.1 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 2.9 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 1.2 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 4.7 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.3 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.6 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 1.5 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.8 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 3.3 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 0.4 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.2 | GO:0032557 | pyrimidine ribonucleotide binding(GO:0032557) |
| 0.0 | 0.9 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 1.0 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.4 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 3.1 | GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors(GO:0016614) |
| 0.0 | 9.7 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 1.4 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 2.7 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.0 | 0.2 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.4 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.3 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 1.1 | GO:0019955 | cytokine binding(GO:0019955) |
| 0.0 | 0.9 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 1.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.3 | GO:0016208 | AMP binding(GO:0016208) |
| 0.0 | 0.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.1 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 2.4 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.5 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 1.2 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.4 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
| 0.0 | 0.4 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 1.7 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 0.3 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.7 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.2 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.0 | 0.5 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.5 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
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