Motif ID: Irf4

Z-value: 0.615


Transcription factors associated with Irf4:

Gene SymbolEntrez IDGene Name
Irf4 ENSMUSG00000021356.3 Irf4



Activity profile for motif Irf4.

activity profile for motif Irf4


Sorted Z-values histogram for motif Irf4

Sorted Z-values for motif Irf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Irf4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_163313661 7.539 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr3_+_90537242 6.141 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr3_+_90537306 6.107 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr11_-_77894096 5.506 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr6_-_87335758 4.807 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr9_+_85842852 4.147 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr13_-_113046357 3.836 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr3_-_142395661 3.729 ENSMUST00000029941.9
ENSMUST00000168967.2
ENSMUST00000090134.5
ENSMUST00000058626.8
Pdlim5



PDZ and LIM domain 5



chr19_-_24225015 3.713 ENSMUST00000099558.4
Tjp2
tight junction protein 2
chr14_+_60732906 3.308 ENSMUST00000162945.1
Spata13
spermatogenesis associated 13
chr2_-_127788854 2.965 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chrX_-_134161928 2.938 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr1_+_61638819 2.934 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr10_+_128706251 2.928 ENSMUST00000054125.8
Pmel
premelanosome protein
chr6_+_71282280 2.925 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr13_-_81570640 2.857 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr6_+_128362919 2.843 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr6_+_82041623 2.793 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chr11_+_119393060 2.725 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chr7_+_58658181 2.662 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr6_-_39118211 2.637 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr11_-_101551837 2.558 ENSMUST00000017290.4
Brca1
breast cancer 1
chr1_-_14310198 2.529 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr4_-_89311021 2.523 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr19_+_56397100 2.376 ENSMUST00000026062.9
Casp7
caspase 7
chr14_-_66124482 2.366 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr6_-_97060407 2.303 ENSMUST00000089295.4
Fam19a4
family with sequence similarity 19, member A4
chr7_-_65370908 2.302 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr10_-_41490335 2.190 ENSMUST00000019965.6
Smpd2
sphingomyelin phosphodiesterase 2, neutral
chr11_-_3539228 2.142 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
Smtn



smoothelin



chr16_-_5255923 2.124 ENSMUST00000139584.1
ENSMUST00000064635.5
Fam86

family with sequence similarity 86

chr15_-_50889691 2.054 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr17_-_6782775 2.029 ENSMUST00000064234.6
Ezr
ezrin
chr14_-_122465677 1.934 ENSMUST00000039118.6
Zic5
zinc finger protein of the cerebellum 5
chr19_-_58454580 1.894 ENSMUST00000129100.1
ENSMUST00000123957.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr10_+_94575257 1.878 ENSMUST00000121471.1
Tmcc3
transmembrane and coiled coil domains 3
chr19_-_58455398 1.814 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_+_66468364 1.798 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr19_-_58455161 1.764 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr8_+_105170668 1.764 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta



chr4_+_115000156 1.732 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr5_-_104021919 1.726 ENSMUST00000031251.9
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr1_+_16688405 1.640 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr10_+_86022189 1.622 ENSMUST00000120344.1
ENSMUST00000117597.1
Fbxo7

F-box protein 7

chr2_-_51934644 1.570 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr4_+_115000174 1.520 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr17_+_34203527 1.514 ENSMUST00000025197.5
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_-_141010759 1.460 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr17_-_30612613 1.431 ENSMUST00000167624.1
ENSMUST00000024823.6
Glo1

glyoxalase 1

chr14_+_120275669 1.385 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr3_+_89421619 1.379 ENSMUST00000094378.3
ENSMUST00000137793.1
Shc1

src homology 2 domain-containing transforming protein C1

chr18_-_78142119 1.372 ENSMUST00000160639.1
Slc14a1
solute carrier family 14 (urea transporter), member 1
chr16_+_35938972 1.352 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr5_-_104021799 1.316 ENSMUST00000119025.1
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr9_-_116175318 1.299 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr13_-_23710714 1.274 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr2_+_71453276 1.241 ENSMUST00000037210.8
Metap1d
methionyl aminopeptidase type 1D (mitochondrial)
chr16_-_43664145 1.208 ENSMUST00000096065.4
Tigit
T cell immunoreceptor with Ig and ITIM domains
chr10_+_126978690 1.170 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr8_+_128685654 1.155 ENSMUST00000090006.5
Itgb1
integrin beta 1 (fibronectin receptor beta)
chr16_+_43235856 1.140 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr2_+_128126030 1.138 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr18_+_7869707 1.107 ENSMUST00000166062.1
ENSMUST00000169010.1
Wac

WW domain containing adaptor with coiled-coil

chr10_-_64090241 1.049 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr4_-_123139929 1.009 ENSMUST00000030404.4
Ppie
peptidylprolyl isomerase E (cyclophilin E)
chr16_-_24393588 0.990 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr3_-_67375163 0.899 ENSMUST00000166353.1
Gm17402
predicted gene, 17402
chr9_-_114564315 0.811 ENSMUST00000111816.2
Trim71
tripartite motif-containing 71
chrX_+_94636066 0.808 ENSMUST00000096368.3
Gspt2
G1 to S phase transition 2
chr1_+_187215737 0.734 ENSMUST00000160471.1
Gpatch2
G patch domain containing 2
chr7_+_19024387 0.693 ENSMUST00000153976.1
Sympk
symplekin
chr16_+_24393350 0.654 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr13_-_100616911 0.615 ENSMUST00000168772.1
ENSMUST00000163163.1
ENSMUST00000022137.7
Marveld2


MARVEL (membrane-associating) domain containing 2


chr16_-_35939082 0.561 ENSMUST00000081933.7
ENSMUST00000114885.1
Dtx3l

deltex 3-like (Drosophila)

chr9_+_35267857 0.549 ENSMUST00000034543.4
Rpusd4
RNA pseudouridylate synthase domain containing 4
chr13_+_96082158 0.548 ENSMUST00000185178.1
Gm17190
predicted gene 17190
chrX_+_150547375 0.546 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr4_-_107178282 0.535 ENSMUST00000058585.7
Tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr1_+_99772765 0.522 ENSMUST00000086738.3
Cntnap5b
contactin associated protein-like 5B
chr7_-_16286744 0.516 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
Ccdc9


coiled-coil domain containing 9


chr1_-_57406443 0.500 ENSMUST00000160837.1
ENSMUST00000161780.1
Tyw5

tRNA-yW synthesizing protein 5

chr2_-_52335134 0.500 ENSMUST00000075301.3
Neb
nebulin
chr1_+_58393119 0.479 ENSMUST00000050552.8
Bzw1
basic leucine zipper and W2 domains 1
chr8_-_78821136 0.425 ENSMUST00000130325.1
ENSMUST00000051867.6
Lsm6

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr1_-_97977233 0.356 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr11_+_78245743 0.344 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr9_+_105053239 0.320 ENSMUST00000035177.8
ENSMUST00000149243.1
Mrpl3

mitochondrial ribosomal protein L3

chr10_-_64090265 0.314 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr13_+_23555023 0.313 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chrM_+_8600 0.308 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr14_-_54409469 0.285 ENSMUST00000000984.4
Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr7_+_19024364 0.271 ENSMUST00000023882.7
Sympk
symplekin
chr10_-_18234930 0.266 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr9_+_45042425 0.260 ENSMUST00000034600.4
Mpzl2
myelin protein zero-like 2
chr11_+_69966896 0.256 ENSMUST00000151515.1
Cldn7
claudin 7
chr7_-_126396715 0.238 ENSMUST00000075671.4
Nfatc2ip
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
chr10_-_78352053 0.237 ENSMUST00000105388.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_-_101171302 0.186 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr9_+_108508005 0.185 ENSMUST00000006838.8
ENSMUST00000134939.1
Qars

glutaminyl-tRNA synthetase

chr17_+_35424870 0.179 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr4_-_136886187 0.144 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr6_-_49214954 0.140 ENSMUST00000031838.7
Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr19_+_33822908 0.131 ENSMUST00000042061.6
Gm5519
predicted pseudogene 5519
chr13_+_5861489 0.127 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr2_-_167631972 0.091 ENSMUST00000060645.6
ENSMUST00000140216.1
ENSMUST00000151365.1
ENSMUST00000109207.3
Ube2v1



ubiquitin-conjugating enzyme E2 variant 1



chr1_+_132008285 0.087 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr10_-_78351711 0.087 ENSMUST00000105390.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr6_-_128362812 0.075 ENSMUST00000112152.1
ENSMUST00000057421.8
ENSMUST00000112151.1
Rhno1


RAD9-HUS1-RAD1 interacting nuclear orphan 1


chrX_+_94367112 0.066 ENSMUST00000113898.1
Apoo
apolipoprotein O
chr6_+_35177386 0.036 ENSMUST00000043815.9
Nup205
nucleoporin 205
chr7_+_28741968 0.030 ENSMUST00000094632.4
Sars2
seryl-aminoacyl-tRNA synthetase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0006553 lysine metabolic process(GO:0006553)
1.6 4.8 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.9 3.7 GO:1903011 negative regulation of bone development(GO:1903011)
0.9 2.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.8 2.4 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.7 2.0 GO:1900041 intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.6 7.5 GO:0048664 neuron fate determination(GO:0048664)
0.4 1.3 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.4 2.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 3.3 GO:0033504 floor plate development(GO:0033504)
0.4 1.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.4 1.5 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.4 3.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.4 2.9 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.4 2.8 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.3 1.6 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 1.3 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)
0.3 3.0 GO:0042447 hormone catabolic process(GO:0042447)
0.3 2.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.3 1.1 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 0.8 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 2.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 1.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 1.4 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.2 1.4 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.2 0.5 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 2.4 GO:0031670 cellular response to nutrient(GO:0031670)
0.1 12.2 GO:0051592 response to calcium ion(GO:0051592)
0.1 1.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.1 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.1 1.4 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 0.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.3 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.1 2.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 1.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 7.9 GO:0051963 regulation of synapse assembly(GO:0051963)
0.1 1.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 1.4 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.1 2.7 GO:0015914 phospholipid transport(GO:0015914)
0.1 2.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 3.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 2.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.0 GO:0045070 protein peptidyl-prolyl isomerization(GO:0000413) positive regulation of viral genome replication(GO:0045070)
0.0 0.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.4 GO:0009404 toxin metabolic process(GO:0009404)
0.0 1.4 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 1.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.0 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 2.9 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.0 0.6 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.6 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 2.1 GO:0009411 response to UV(GO:0009411)
0.0 1.9 GO:0001843 neural tube closure(GO:0001843)
0.0 0.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0032585 multivesicular body membrane(GO:0032585)
0.6 1.2 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.5 2.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 4.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 2.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 1.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 0.8 GO:0018444 translation release factor complex(GO:0018444)
0.3 2.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.3 1.3 GO:1990357 terminal web(GO:1990357)
0.2 1.5 GO:0042825 TAP complex(GO:0042825)
0.2 0.6 GO:0033010 paranodal junction(GO:0033010)
0.2 3.7 GO:0005921 gap junction(GO:0005921)
0.1 3.0 GO:0097546 ciliary base(GO:0097546)
0.1 0.3 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 5.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.0 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 3.3 GO:0030175 filopodium(GO:0030175)
0.0 5.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 22.5 GO:0005730 nucleolus(GO:0005730)
0.0 2.2 GO:0005901 caveola(GO:0005901)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.0 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 2.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 5.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.6 2.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 1.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.4 3.0 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.4 2.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.4 1.5 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.3 1.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.3 1.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 1.2 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 2.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 1.4 GO:0015265 urea channel activity(GO:0015265)
0.2 6.7 GO:0071837 HMG box domain binding(GO:0071837)
0.2 2.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 3.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 2.0 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 2.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 2.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.7 GO:0042805 actinin binding(GO:0042805)
0.1 0.4 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.9 GO:0005518 collagen binding(GO:0005518)
0.1 5.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0016594 glycine binding(GO:0016594)
0.0 2.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.1 GO:0045502 dynein binding(GO:0045502)
0.0 3.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.0 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 10.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0046977 TAP binding(GO:0046977)
0.0 2.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)