Motif ID: Irf5_Irf6
Z-value: 0.633


Transcription factors associated with Irf5_Irf6:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Irf5 | ENSMUSG00000029771.6 | Irf5 |
Irf6 | ENSMUSG00000026638.9 | Irf6 |
Top targets:
Showing 1 to 20 of 60 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 35 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 12.1 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
0.2 | 7.2 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.5 | 5.4 | GO:0045056 | transcytosis(GO:0045056) |
1.2 | 4.7 | GO:0009597 | detection of virus(GO:0009597) |
0.7 | 4.6 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
0.6 | 4.6 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.3 | 4.4 | GO:0048664 | neuron fate determination(GO:0048664) |
0.2 | 4.2 | GO:0071260 | negative regulation of striated muscle cell apoptotic process(GO:0010664) cellular response to mechanical stimulus(GO:0071260) |
0.0 | 3.7 | GO:0045216 | cell-cell junction organization(GO:0045216) |
0.8 | 2.3 | GO:1900041 | intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896) |
0.0 | 1.7 | GO:0071594 | T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594) |
0.0 | 1.6 | GO:0002066 | columnar/cuboidal epithelial cell development(GO:0002066) |
0.2 | 1.5 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) |
0.1 | 1.4 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.0 | 1.4 | GO:0043627 | response to estrogen(GO:0043627) |
0.1 | 1.3 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
0.1 | 1.1 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.2 | 1.0 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
0.0 | 1.0 | GO:0051642 | centrosome localization(GO:0051642) |
0.3 | 0.9 | GO:0008582 | regulation of synaptic growth at neuromuscular junction(GO:0008582) skeletal muscle fiber differentiation(GO:0098528) |
Gene overrepresentation in cellular_component category:
Showing 1 to 17 of 17 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 11.4 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 7.9 | GO:0045177 | apical part of cell(GO:0045177) |
0.3 | 6.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 5.4 | GO:0031526 | brush border membrane(GO:0031526) |
0.1 | 4.7 | GO:0032587 | ruffle membrane(GO:0032587) |
0.5 | 4.6 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.6 | 2.3 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.1 | 1.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 1.4 | GO:0005876 | spindle microtubule(GO:0005876) |
0.0 | 1.4 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 0.9 | GO:0042825 | TAP complex(GO:0042825) |
0.0 | 0.8 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 0.7 | GO:0016580 | Sin3 complex(GO:0016580) |
0.1 | 0.5 | GO:0005796 | Golgi lumen(GO:0005796) |
0.1 | 0.5 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
0.0 | 0.5 | GO:0090544 | BAF-type complex(GO:0090544) |
0.0 | 0.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 21 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 7.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.2 | 7.2 | GO:0042805 | actinin binding(GO:0042805) |
0.1 | 5.7 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
1.1 | 5.4 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.4 | 5.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.2 | 4.6 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 4.4 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.7 | 4.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.2 | 2.3 | GO:0044548 | S100 protein binding(GO:0044548) |
0.0 | 1.7 | GO:0004519 | endonuclease activity(GO:0004519) |
0.0 | 1.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 1.4 | GO:0030332 | cyclin binding(GO:0030332) |
0.2 | 0.9 | GO:0023029 | peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980) |
0.0 | 0.8 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.2 | 0.7 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
0.0 | 0.7 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.1 | 0.5 | GO:0003680 | AT DNA binding(GO:0003680) |
0.0 | 0.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.1 | 0.2 | GO:0004127 | cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041) |
0.0 | 0.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |