Motif ID: Irx4

Z-value: 0.209


Transcription factors associated with Irx4:

Gene SymbolEntrez IDGene Name
Irx4 ENSMUSG00000021604.9 Irx4



Activity profile for motif Irx4.

activity profile for motif Irx4


Sorted Z-values histogram for motif Irx4

Sorted Z-values for motif Irx4



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45311538 1.565 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr9_-_58202281 1.316 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr6_-_3494587 0.729 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr2_-_79908428 0.694 ENSMUST00000102652.3
ENSMUST00000102651.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr16_+_17146937 0.578 ENSMUST00000115706.1
ENSMUST00000069064.4
 Ydjc

YdjC homolog (bacterial)

chr2_-_79908389 0.515 ENSMUST00000090756.4
 Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr8_+_84872105 0.476 ENSMUST00000136026.1
ENSMUST00000170296.1
 Syce2

synaptonemal complex central element protein 2

chr4_+_48663502 0.413 ENSMUST00000030033.4
 Murc
muscle-related coiled-coil protein
chr4_-_76344227 0.186 ENSMUST00000050757.9
 Ptprd
protein tyrosine phosphatase, receptor type, D
chr18_-_37178493 0.173 ENSMUST00000181887.1
ENSMUST00000180516.1
 Gm10544

predicted gene 10544

chr3_-_57651667 0.103 ENSMUST00000160959.1
 Commd2
COMM domain containing 2
chr15_-_35938186 0.098 ENSMUST00000014457.8
 Cox6c
cytochrome c oxidase subunit VIc
chr15_-_35938009 0.082 ENSMUST00000156915.1
 Cox6c
cytochrome c oxidase subunit VIc
chr3_+_27317028 0.048 ENSMUST00000046383.5
ENSMUST00000174840.1
 Tnfsf10

tumor necrosis factor (ligand) superfamily, member 10

chr17_-_27133902 0.023 ENSMUST00000119227.1
ENSMUST00000025045.8
 Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 1.3 GO:0045773 positive regulation of axon extension(GO:0045773)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0000801 central element(GO:0000801)
0.1 1.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.6 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)