Motif ID: Jun
Z-value: 0.434
Transcription factors associated with Jun:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Jun | ENSMUSG00000052684.3 | Jun |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Jun | mm10_v2_chr4_-_95052188_95052222 | 0.26 | 3.0e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.3 | GO:1904451 | regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
| 0.8 | 4.7 | GO:1902847 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) |
| 0.7 | 2.0 | GO:0043465 | regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003) |
| 0.7 | 3.3 | GO:0060161 | positive regulation of dopamine receptor signaling pathway(GO:0060161) |
| 0.6 | 4.7 | GO:0009181 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 0.5 | 1.4 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
| 0.4 | 1.7 | GO:1904177 | regulation of adipose tissue development(GO:1904177) |
| 0.4 | 1.7 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.4 | 1.1 | GO:2000852 | regulation of corticosterone secretion(GO:2000852) |
| 0.3 | 1.4 | GO:0006538 | glutamate catabolic process(GO:0006538) |
| 0.3 | 1.2 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.3 | 1.4 | GO:0046133 | pyrimidine ribonucleoside catabolic process(GO:0046133) |
| 0.3 | 0.8 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.3 | 2.0 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.3 | 0.8 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.2 | 0.7 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
| 0.2 | 0.7 | GO:0060364 | frontal suture morphogenesis(GO:0060364) |
| 0.2 | 2.3 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.2 | 1.1 | GO:2000587 | regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 0.2 | 1.0 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.2 | 1.0 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.2 | 1.3 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.2 | 1.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.2 | 1.9 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
| 0.2 | 0.8 | GO:0015705 | iodide transport(GO:0015705) |
| 0.2 | 0.6 | GO:0002513 | tolerance induction to self antigen(GO:0002513) |
| 0.1 | 1.8 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.1 | 0.9 | GO:1900451 | positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.1 | 0.3 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 0.1 | 0.6 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.1 | 0.4 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) |
| 0.1 | 1.7 | GO:0010640 | regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) |
| 0.1 | 0.8 | GO:0051036 | regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.1 | 1.2 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.1 | 0.6 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
| 0.1 | 0.8 | GO:0034134 | toll-like receptor 2 signaling pathway(GO:0034134) negative regulation of cholesterol efflux(GO:0090370) |
| 0.1 | 0.5 | GO:0071360 | cellular response to exogenous dsRNA(GO:0071360) |
| 0.1 | 0.2 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.1 | 0.3 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.1 | 0.5 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.1 | 0.5 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 2.2 | GO:0034113 | heterotypic cell-cell adhesion(GO:0034113) |
| 0.1 | 0.5 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.1 | 1.0 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 0.3 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
| 0.1 | 1.4 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.1 | 1.5 | GO:0010039 | response to iron ion(GO:0010039) |
| 0.1 | 0.3 | GO:0045084 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) |
| 0.1 | 0.2 | GO:0048388 | endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401) |
| 0.1 | 1.3 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.1 | 0.3 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.1 | 0.3 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.1 | 1.0 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.1 | 0.6 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 0.4 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.1 | 0.4 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.1 | 1.4 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 0.3 | GO:0032911 | nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.0 | 2.7 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 0.5 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.2 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.0 | 0.3 | GO:1904587 | glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587) |
| 0.0 | 0.4 | GO:0002467 | germinal center formation(GO:0002467) |
| 0.0 | 0.7 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.0 | 0.5 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 0.3 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.0 | 0.4 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.0 | 1.0 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.1 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.4 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
| 0.0 | 0.5 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.0 | 0.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 0.3 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.0 | 0.5 | GO:0033198 | response to ATP(GO:0033198) |
| 0.0 | 0.1 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
| 0.0 | 0.4 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.0 | 0.2 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.0 | 0.3 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.0 | GO:0071873 | response to norepinephrine(GO:0071873) |
| 0.0 | 0.2 | GO:0044243 | collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243) |
| 0.0 | 0.0 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 0.5 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.0 | 0.0 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 0.0 | 0.1 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.3 | GO:1990795 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) |
| 0.8 | 2.3 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.7 | 4.7 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418) |
| 0.5 | 0.5 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.3 | 1.3 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.3 | 2.3 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.2 | 1.7 | GO:0005638 | lamin filament(GO:0005638) |
| 0.2 | 1.4 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.2 | 3.3 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 0.6 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.1 | 1.2 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 0.7 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 0.3 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.1 | 0.8 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.1 | 2.0 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 1.1 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 1.6 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 1.1 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 0.2 | GO:0070449 | elongin complex(GO:0070449) |
| 0.1 | 0.7 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 0.5 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 2.5 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 0.5 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.4 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 0.0 | 0.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.3 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.3 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.5 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.0 | 1.1 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 1.2 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 1.6 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 1.8 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 2.3 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 1.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.1 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 1.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.1 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.4 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 1.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.1 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 0.0 | 4.7 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.2 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 4.7 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.5 | 1.9 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.4 | 3.3 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.4 | 1.1 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153) |
| 0.3 | 1.0 | GO:0004471 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) |
| 0.3 | 1.2 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.3 | 1.5 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.3 | 2.0 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.3 | 1.4 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.2 | 1.2 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.2 | 0.7 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) |
| 0.2 | 2.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.2 | 1.4 | GO:0070728 | leucine binding(GO:0070728) |
| 0.2 | 4.7 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.2 | 1.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.2 | 0.8 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.2 | 0.6 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.1 | 3.3 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.1 | 1.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 1.3 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 1.6 | GO:0010181 | FMN binding(GO:0010181) |
| 0.1 | 1.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.5 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.1 | 0.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 1.4 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 1.0 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.1 | 0.5 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.1 | 0.8 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
| 0.1 | 2.3 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 0.6 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.1 | 1.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 0.4 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.1 | 1.7 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 1.2 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 0.7 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 2.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 0.7 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.2 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.1 | 0.2 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.0 | 0.5 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.9 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.4 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.0 | 0.7 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 0.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.3 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 0.2 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.0 | 1.7 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 0.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.3 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 1.8 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 1.4 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
| 0.0 | 1.0 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.2 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.0 | 0.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.1 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.0 | 1.7 | GO:0030295 | protein kinase activator activity(GO:0030295) |
| 0.0 | 0.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 1.4 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
| 0.0 | 0.4 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 0.4 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.0 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.0 | 4.6 | GO:0032561 | guanyl ribonucleotide binding(GO:0032561) |
| 0.0 | 0.6 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.0 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.0 | 0.0 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
