Motif ID: Klf15

Z-value: 1.160


Transcription factors associated with Klf15:

Gene SymbolEntrez IDGene Name
Klf15 ENSMUSG00000030087.5 Klf15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf15mm10_v2_chr6_+_90462562_904625870.113.5e-01Click!


Activity profile for motif Klf15.

activity profile for motif Klf15


Sorted Z-values histogram for motif Klf15

Sorted Z-values for motif Klf15



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_56971762 15.851 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr18_-_89769479 10.912 ENSMUST00000097495.3
 Dok6
docking protein 6
chr17_+_46297917 9.861 ENSMUST00000166617.1
ENSMUST00000170271.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr1_-_56972437 9.297 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr11_+_24076529 9.106 ENSMUST00000148087.1
 Gm12063
predicted gene 12063
chr11_+_98348404 8.235 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_+_46396439 7.999 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr18_-_66291770 7.690 ENSMUST00000130300.1
 Ccbe1
collagen and calcium binding EGF domains 1
chr7_+_126776939 7.346 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr1_-_72536930 7.223 ENSMUST00000047786.5
 March4
membrane-associated ring finger (C3HC4) 4
chr6_-_148444336 7.198 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr2_-_5714490 6.693 ENSMUST00000044009.7
 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr11_+_50602072 6.592 ENSMUST00000040523.8
 Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chrX_-_136868537 6.266 ENSMUST00000058814.6
 Rab9b
RAB9B, member RAS oncogene family
chr11_+_69765970 6.229 ENSMUST00000108642.1
ENSMUST00000156932.1
 Zbtb4

zinc finger and BTB domain containing 4

chr11_+_69765899 6.136 ENSMUST00000108640.1
ENSMUST00000108639.1
 Zbtb4

zinc finger and BTB domain containing 4

chr5_-_65492984 6.066 ENSMUST00000139122.1
 Smim14
small integral membrane protein 14
chr11_-_97573929 5.788 ENSMUST00000126287.1
ENSMUST00000107590.1
 Srcin1

SRC kinase signaling inhibitor 1

chr5_+_137288273 5.785 ENSMUST00000024099.4
ENSMUST00000085934.3
 Ache

acetylcholinesterase

chr11_-_97574040 5.772 ENSMUST00000107593.1
 Srcin1
SRC kinase signaling inhibitor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 147 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 25.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 12.0 GO:0060074 synapse maturation(GO:0060074)
1.9 11.7 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.4 11.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
2.2 9.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.4 9.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
2.7 8.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.0 8.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 8.0 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
1.9 7.7 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
1.5 7.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.0 6.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.4 6.6 GO:0030574 collagen catabolic process(GO:0030574)
0.2 6.5 GO:0006491 N-glycan processing(GO:0006491)
0.2 6.4 GO:0016578 histone deubiquitination(GO:0016578)
0.1 6.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
2.0 6.0 GO:0071544 diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 5.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.0 5.8 GO:0019695 choline metabolic process(GO:0019695)
0.2 5.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 18.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 16.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 14.5 GO:0042734 presynaptic membrane(GO:0042734)
0.3 12.9 GO:0097440 apical dendrite(GO:0097440)
0.3 11.0 GO:0032590 dendrite membrane(GO:0032590)
0.1 10.6 GO:0008021 synaptic vesicle(GO:0008021)
0.1 10.2 GO:0030175 filopodium(GO:0030175)
0.0 9.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 7.6 GO:0005795 Golgi stack(GO:0005795)
0.1 7.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 6.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 6.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.5 6.0 GO:0000124 SAGA complex(GO:0000124)
0.2 5.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 5.4 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 5.2 GO:0043025 neuronal cell body(GO:0043025)
0.1 4.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 4.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 4.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 14.9 GO:0070412 R-SMAD binding(GO:0070412)
0.4 14.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 12.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.5 12.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 10.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 9.7 GO:0008083 growth factor activity(GO:0008083)
0.7 9.0 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
2.7 8.2 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.3 8.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 8.0 GO:0005096 GTPase activator activity(GO:0005096)
0.1 7.7 GO:0005518 collagen binding(GO:0005518)
0.1 7.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.7 6.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.9 6.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 6.3 GO:0019003 GDP binding(GO:0019003)
1.0 6.0 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.2 5.9 GO:0030552 cAMP binding(GO:0030552)
1.4 5.8 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 5.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 5.0 GO:0003714 transcription corepressor activity(GO:0003714)