Motif ID: Klf15
Z-value: 1.160
Transcription factors associated with Klf15:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Klf15 | ENSMUSG00000030087.5 | Klf15 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Klf15 | mm10_v2_chr6_+_90462562_90462587 | 0.11 | 3.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.7 | 8.2 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
2.2 | 9.0 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
2.0 | 6.0 | GO:0071544 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544) |
1.9 | 11.7 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
1.9 | 7.7 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
1.6 | 25.1 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
1.5 | 7.3 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
1.4 | 4.1 | GO:0060596 | mammary placode formation(GO:0060596) |
1.2 | 3.7 | GO:1902460 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
1.2 | 3.7 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
1.1 | 3.2 | GO:1904742 | protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742) |
1.0 | 3.1 | GO:0061303 | noradrenergic neuron differentiation(GO:0003357) soft palate development(GO:0060023) cornea development in camera-type eye(GO:0061303) |
1.0 | 8.1 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
1.0 | 5.8 | GO:0019695 | choline metabolic process(GO:0019695) |
1.0 | 3.8 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
1.0 | 6.7 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
0.9 | 3.7 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.9 | 4.5 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
0.8 | 3.3 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.8 | 3.1 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
0.8 | 3.8 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.7 | 2.6 | GO:0021764 | amygdala development(GO:0021764) |
0.6 | 3.9 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.6 | 3.2 | GO:0010991 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
0.6 | 3.9 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
0.6 | 4.3 | GO:0032811 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811) |
0.6 | 3.0 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
0.6 | 4.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.6 | 2.9 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
0.5 | 4.3 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
0.5 | 2.7 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
0.5 | 4.3 | GO:0035635 | entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535) |
0.5 | 2.7 | GO:0032911 | nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.5 | 2.1 | GO:0043974 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) |
0.4 | 3.4 | GO:0006537 | glutamate biosynthetic process(GO:0006537) proline biosynthetic process(GO:0006561) |
0.4 | 1.7 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
0.4 | 3.7 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
0.4 | 6.6 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.4 | 4.1 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.4 | 11.6 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
0.4 | 0.4 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
0.4 | 3.4 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.4 | 9.0 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.4 | 1.8 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
0.4 | 3.6 | GO:0006691 | leukotriene metabolic process(GO:0006691) |
0.4 | 2.5 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.3 | 5.1 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.3 | 5.1 | GO:0042297 | vocal learning(GO:0042297) imitative learning(GO:0098596) observational learning(GO:0098597) learned vocalization behavior or vocal learning(GO:0098598) |
0.3 | 1.6 | GO:0098903 | regulation of membrane repolarization during action potential(GO:0098903) |
0.3 | 12.0 | GO:0060074 | synapse maturation(GO:0060074) |
0.3 | 1.6 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.3 | 1.9 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
0.3 | 5.0 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.3 | 4.4 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.3 | 0.9 | GO:0018094 | protein polyglycylation(GO:0018094) |
0.3 | 4.9 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.3 | 1.4 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
0.3 | 3.9 | GO:0072010 | renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
0.3 | 1.1 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.3 | 0.6 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.3 | 1.9 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.3 | 0.8 | GO:0003096 | renal sodium ion transport(GO:0003096) |
0.2 | 6.5 | GO:0006491 | N-glycan processing(GO:0006491) |
0.2 | 1.5 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.2 | 1.4 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.2 | 0.7 | GO:0019085 | early viral transcription(GO:0019085) |
0.2 | 1.1 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.2 | 2.6 | GO:0000059 | protein import into nucleus, docking(GO:0000059) |
0.2 | 6.4 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.2 | 2.8 | GO:0055090 | acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) |
0.2 | 4.5 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.2 | 8.0 | GO:1901381 | positive regulation of potassium ion transmembrane transport(GO:1901381) |
0.2 | 5.9 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.2 | 4.4 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
0.2 | 3.4 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
0.2 | 5.8 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.2 | 0.7 | GO:1903897 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) regulation of PERK-mediated unfolded protein response(GO:1903897) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
0.2 | 0.6 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
0.2 | 5.6 | GO:1904030 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
0.1 | 0.9 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.1 | 0.9 | GO:0072610 | interleukin-12 secretion(GO:0072610) regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184) |
0.1 | 0.8 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.1 | 1.4 | GO:0097186 | amelogenesis(GO:0097186) |
0.1 | 1.8 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
0.1 | 1.5 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 1.4 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
0.1 | 0.5 | GO:0044337 | canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
0.1 | 3.9 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
0.1 | 1.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
0.1 | 5.1 | GO:0035418 | protein localization to synapse(GO:0035418) |
0.1 | 0.8 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
0.1 | 1.2 | GO:2001223 | negative regulation of neuron migration(GO:2001223) |
0.1 | 0.5 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.1 | 0.4 | GO:0009597 | detection of virus(GO:0009597) |
0.1 | 3.8 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.1 | 2.5 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.1 | 1.5 | GO:0001553 | luteinization(GO:0001553) |
0.1 | 1.0 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) |
0.1 | 1.1 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.1 | 2.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.1 | 6.3 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.1 | 3.2 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
0.1 | 0.3 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
0.1 | 2.6 | GO:0007520 | myoblast fusion(GO:0007520) |
0.1 | 3.6 | GO:1902850 | mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850) |
0.1 | 0.5 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
0.1 | 0.3 | GO:0033092 | positive regulation of immature T cell proliferation in thymus(GO:0033092) |
0.1 | 2.0 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
0.1 | 4.0 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.1 | 0.1 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.1 | 2.4 | GO:0006006 | glucose metabolic process(GO:0006006) |
0.1 | 4.1 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.1 | 2.9 | GO:0042035 | regulation of cytokine biosynthetic process(GO:0042035) |
0.1 | 0.5 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
0.1 | 1.8 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
0.1 | 0.2 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) endothelial cell-cell adhesion(GO:0071603) |
0.1 | 1.1 | GO:0051898 | negative regulation of protein kinase B signaling(GO:0051898) |
0.1 | 1.0 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.1 | 0.4 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
0.1 | 0.7 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.0 | 1.7 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.0 | 3.9 | GO:0007631 | feeding behavior(GO:0007631) |
0.0 | 2.7 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.0 | 2.1 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 1.2 | GO:0090004 | positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
0.0 | 0.5 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.0 | 1.3 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
0.0 | 2.6 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.0 | 1.5 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
0.0 | 0.2 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
0.0 | 0.1 | GO:0042045 | epithelial fluid transport(GO:0042045) |
0.0 | 1.2 | GO:0007019 | microtubule depolymerization(GO:0007019) |
0.0 | 0.5 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
0.0 | 0.7 | GO:0061036 | positive regulation of cartilage development(GO:0061036) |
0.0 | 1.5 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation(GO:0033138) |
0.0 | 0.4 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.0 | 0.1 | GO:1900452 | regulation of long term synaptic depression(GO:1900452) |
0.0 | 1.0 | GO:0048286 | lung alveolus development(GO:0048286) |
0.0 | 0.2 | GO:0070831 | basement membrane assembly(GO:0070831) |
0.0 | 0.1 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
0.0 | 2.0 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
0.0 | 0.6 | GO:0034612 | response to tumor necrosis factor(GO:0034612) |
0.0 | 0.6 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
0.0 | 0.5 | GO:0050714 | positive regulation of protein secretion(GO:0050714) |
0.0 | 0.7 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
0.0 | 0.4 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
0.0 | 1.0 | GO:0050691 | positive regulation of defense response to virus by host(GO:0002230) regulation of defense response to virus by host(GO:0050691) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.8 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.9 | 4.3 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.6 | 3.9 | GO:0008091 | spectrin(GO:0008091) |
0.5 | 6.0 | GO:0000124 | SAGA complex(GO:0000124) |
0.5 | 3.4 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.4 | 4.3 | GO:0032584 | growth cone membrane(GO:0032584) |
0.4 | 1.1 | GO:0005595 | collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934) |
0.3 | 12.9 | GO:0097440 | apical dendrite(GO:0097440) |
0.3 | 11.0 | GO:0032590 | dendrite membrane(GO:0032590) |
0.3 | 4.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.3 | 3.4 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.2 | 1.7 | GO:0070695 | FHF complex(GO:0070695) |
0.2 | 4.1 | GO:0097470 | ribbon synapse(GO:0097470) |
0.2 | 3.4 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.2 | 14.5 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.2 | 1.4 | GO:1990246 | uniplex complex(GO:1990246) |
0.2 | 2.1 | GO:0042599 | lamellar body(GO:0042599) |
0.2 | 3.6 | GO:0097228 | sperm principal piece(GO:0097228) |
0.2 | 1.6 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.2 | 5.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.2 | 0.5 | GO:0031251 | PAN complex(GO:0031251) |
0.2 | 18.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.1 | 7.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.1 | 3.1 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 6.3 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.1 | 0.6 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.1 | 1.0 | GO:0043196 | varicosity(GO:0043196) |
0.1 | 1.0 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.1 | 4.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.1 | 7.6 | GO:0005795 | Golgi stack(GO:0005795) |
0.1 | 1.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.1 | 4.8 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 2.1 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.1 | 6.4 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.1 | 10.2 | GO:0030175 | filopodium(GO:0030175) |
0.1 | 1.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 4.0 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.1 | 3.3 | GO:0016592 | mediator complex(GO:0016592) |
0.1 | 2.6 | GO:0031901 | early endosome membrane(GO:0031901) |
0.1 | 3.1 | GO:0060170 | ciliary membrane(GO:0060170) |
0.1 | 1.1 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.1 | 0.8 | GO:0046930 | pore complex(GO:0046930) |
0.1 | 10.6 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.1 | 5.4 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
0.1 | 1.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.1 | 2.1 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.1 | 0.4 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 9.7 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 4.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.3 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.0 | 16.4 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
0.0 | 1.2 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 1.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 2.8 | GO:0036064 | ciliary basal body(GO:0036064) |
0.0 | 1.5 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 2.0 | GO:0009986 | cell surface(GO:0009986) |
0.0 | 2.3 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 4.3 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 1.8 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 2.8 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.0 | 0.1 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.0 | 1.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 2.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 1.5 | GO:0043679 | axon terminus(GO:0043679) |
0.0 | 1.6 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 3.9 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
0.0 | 5.2 | GO:0043025 | neuronal cell body(GO:0043025) |
0.0 | 0.3 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
0.0 | 0.7 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.7 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.7 | 8.2 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
1.4 | 5.8 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
1.0 | 6.0 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
0.9 | 6.3 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.8 | 3.1 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.8 | 4.6 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.7 | 6.4 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.7 | 4.3 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.7 | 9.0 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
0.6 | 3.0 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.6 | 3.0 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.5 | 2.6 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.5 | 2.5 | GO:0008808 | cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) |
0.5 | 12.4 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.5 | 3.9 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.5 | 1.8 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.4 | 14.9 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.4 | 14.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.4 | 1.5 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.4 | 4.1 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.3 | 12.8 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.3 | 2.7 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.3 | 2.9 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.3 | 1.4 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.3 | 8.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.3 | 1.4 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.3 | 0.8 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
0.2 | 4.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.2 | 1.9 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821) |
0.2 | 1.4 | GO:0045545 | syndecan binding(GO:0045545) |
0.2 | 2.3 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.2 | 10.9 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.2 | 4.1 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.2 | 1.2 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.2 | 2.4 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
0.2 | 1.5 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
0.2 | 3.9 | GO:0030506 | ankyrin binding(GO:0030506) |
0.2 | 5.9 | GO:0030552 | cAMP binding(GO:0030552) |
0.2 | 1.9 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.1 | 3.4 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
0.1 | 2.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 3.8 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.1 | 3.6 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.1 | 0.8 | GO:0019841 | retinol binding(GO:0019841) |
0.1 | 2.5 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.1 | 1.6 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.1 | 1.0 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 2.7 | GO:0008483 | transaminase activity(GO:0008483) |
0.1 | 7.7 | GO:0005518 | collagen binding(GO:0005518) |
0.1 | 2.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.1 | 9.7 | GO:0008083 | growth factor activity(GO:0008083) |
0.1 | 4.4 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
0.1 | 4.5 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.1 | 6.3 | GO:0019003 | GDP binding(GO:0019003) |
0.1 | 1.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.1 | 2.1 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.1 | 2.6 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.1 | 1.5 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.1 | 2.5 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 7.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.1 | 1.9 | GO:0035064 | methylated histone binding(GO:0035064) |
0.1 | 0.9 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.1 | 0.6 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.1 | 1.5 | GO:0030507 | spectrin binding(GO:0030507) |
0.1 | 0.5 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.1 | 1.5 | GO:0042805 | actinin binding(GO:0042805) |
0.1 | 3.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.1 | 1.7 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.1 | 0.7 | GO:0031559 | oxidosqualene cyclase activity(GO:0031559) |
0.0 | 2.4 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.2 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
0.0 | 2.2 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.5 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 3.8 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.0 | 0.1 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.0 | 3.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.0 | 1.3 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 5.4 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 3.2 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.0 | 3.2 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.0 | 2.2 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 0.3 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.0 | 1.0 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 2.1 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 2.6 | GO:0051117 | ATPase binding(GO:0051117) |
0.0 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 2.9 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 2.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 8.0 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.2 | GO:0070330 | aromatase activity(GO:0070330) |
0.0 | 5.0 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 1.3 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 1.4 | GO:0005262 | calcium channel activity(GO:0005262) |
0.0 | 0.2 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 1.3 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.8 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.7 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
0.0 | 0.1 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.0 | 1.7 | GO:0061659 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
0.0 | 4.2 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
0.0 | 2.0 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 1.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |