Motif ID: Klf7

Z-value: 0.527


Transcription factors associated with Klf7:

Gene SymbolEntrez IDGene Name
Klf7 ENSMUSG00000025959.7 Klf7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf7mm10_v2_chr1_-_64121456_641214910.291.4e-02Click!


Activity profile for motif Klf7.

activity profile for motif Klf7


Sorted Z-values histogram for motif Klf7

Sorted Z-values for motif Klf7



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf7

PNG image of the network

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Top targets:


Showing 1 to 20 of 92 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_897782 3.528 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr2_-_156312470 3.406 ENSMUST00000079125.6
Scand1
SCAN domain-containing 1
chr6_-_88875035 2.883 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr12_-_4592927 2.546 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr5_+_137778849 2.303 ENSMUST00000126126.1
ENSMUST00000031739.4
Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr1_-_138847579 2.123 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr5_-_137741601 2.014 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr6_-_88874597 1.980 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
Podxl2


podocalyxin-like 2


chr3_+_28263205 1.769 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr4_+_107830958 1.385 ENSMUST00000106731.2
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr2_+_119047116 1.319 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr12_+_49382791 1.281 ENSMUST00000179669.1
Foxg1
forkhead box G1
chr9_-_32344237 1.186 ENSMUST00000034533.5
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr12_+_49383007 1.137 ENSMUST00000021333.3
Foxg1
forkhead box G1
chr6_+_52714219 1.090 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr2_+_119047129 1.066 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr15_-_102722150 1.009 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr3_+_106721893 0.977 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
Lrif1



ligand dependent nuclear receptor interacting factor 1



chr1_-_23383149 0.952 ENSMUST00000027343.5
Ogfrl1
opioid growth factor receptor-like 1
chr15_-_102722120 0.916 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.9 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.7 3.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.8 2.4 GO:0021852 pyramidal neuron migration(GO:0021852)
0.2 2.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 2.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.4 2.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 2.0 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.4 1.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.5 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.2 1.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 1.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.4 1.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.9 GO:0006970 response to osmotic stress(GO:0006970)
0.3 0.8 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.0 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.7 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.7 GO:0043983 histone H4-K12 acetylation(GO:0043983)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 GO:0055037 recycling endosome(GO:0055037)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.2 GO:0030315 T-tubule(GO:0030315)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.2 0.7 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.5 3.5 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 1.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 1.8 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.8 GO:0043130 ubiquitin binding(GO:0043130)
0.3 1.4 GO:0038025 reelin receptor activity(GO:0038025)
0.2 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 0.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.5 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)