Motif ID: Klf8

Z-value: 1.121


Transcription factors associated with Klf8:

Gene SymbolEntrez IDGene Name
Klf8 ENSMUSG00000041649.7 Klf8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf8mm10_v2_chrX_+_153237748_153237748-0.671.6e-10Click!


Activity profile for motif Klf8.

activity profile for motif Klf8


Sorted Z-values histogram for motif Klf8

Sorted Z-values for motif Klf8



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_70851189 25.158 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr6_-_72788952 17.122 ENSMUST00000114053.2
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr9_-_8004585 13.350 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr7_-_144939823 11.576 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr14_-_103843685 11.012 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr4_+_46450892 10.987 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr18_-_74961252 10.508 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr13_-_60177357 10.318 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr2_-_36105271 9.575 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr1_-_20820213 9.156 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr7_+_4119556 8.892 ENSMUST00000079415.5
Ttyh1
tweety homolog 1 (Drosophila)
chr7_+_4119525 8.878 ENSMUST00000119661.1
ENSMUST00000129423.1
Ttyh1

tweety homolog 1 (Drosophila)

chr7_-_127026479 8.846 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_+_172550991 8.503 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr11_-_109473220 7.636 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_-_32222233 7.396 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr1_+_172499948 7.246 ENSMUST00000111230.1
Tagln2
transgelin 2
chrX_+_96096034 6.994 ENSMUST00000117399.1
Msn
moesin
chr18_-_78206408 6.863 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr13_+_48261427 6.532 ENSMUST00000021810.1
Id4
inhibitor of DNA binding 4
chr5_-_114690974 6.435 ENSMUST00000012028.7
Gltp
glycolipid transfer protein
chr15_+_78926720 6.174 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr7_-_31055594 5.873 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr2_-_165473187 5.818 ENSMUST00000029208.8
ENSMUST00000109279.2
Slc13a3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr3_+_87948666 5.815 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr7_-_100656953 5.624 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr19_+_25610533 5.616 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr9_+_66158206 5.597 ENSMUST00000034944.2
Dapk2
death-associated protein kinase 2
chr12_-_69228167 5.569 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr3_-_89393294 5.426 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr3_+_146500071 5.367 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr14_+_65358661 5.207 ENSMUST00000066994.6
Zfp395
zinc finger protein 395
chr10_+_94514825 5.191 ENSMUST00000065060.5
Tmcc3
transmembrane and coiled coil domains 3
chr2_-_156839790 5.168 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr11_-_5261558 5.056 ENSMUST00000020662.8
Kremen1
kringle containing transmembrane protein 1
chr10_-_58675631 4.990 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr15_+_39006272 4.919 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr1_-_75505641 4.737 ENSMUST00000155084.1
Obsl1
obscurin-like 1
chr15_-_75909543 4.707 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr3_+_146499828 4.633 ENSMUST00000090031.5
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr16_-_18811615 4.629 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr1_+_191098414 4.610 ENSMUST00000027943.4
Batf3
basic leucine zipper transcription factor, ATF-like 3
chr3_+_90541146 4.595 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100a16


S100 calcium binding protein A16


chr7_+_126847908 4.579 ENSMUST00000147257.1
ENSMUST00000139174.1
Doc2a

double C2, alpha

chr12_+_53248677 4.562 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr3_+_146499850 4.558 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr17_-_70851710 4.541 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr18_+_74442500 4.529 ENSMUST00000074157.6
Myo5b
myosin VB
chr7_-_31054815 4.444 ENSMUST00000071697.4
ENSMUST00000108110.3
Fxyd1

FXYD domain-containing ion transport regulator 1

chr2_+_27886416 4.404 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr7_-_139582790 4.347 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr13_-_29984219 4.344 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr7_+_112427706 4.338 ENSMUST00000033030.7
Parva
parvin, alpha
chr4_-_97778042 4.261 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_+_144838590 4.202 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr12_+_109452833 4.186 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chr13_-_3918157 4.108 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr10_-_13388753 4.076 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr16_+_93683184 4.032 ENSMUST00000039620.6
Cbr3
carbonyl reductase 3
chr3_+_121723515 3.961 ENSMUST00000029771.8
F3
coagulation factor III
chr10_-_13388830 3.840 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr10_+_4710119 3.772 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr11_+_108920800 3.730 ENSMUST00000140821.1
Axin2
axin2
chr17_+_86963077 3.714 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr19_-_10240689 3.699 ENSMUST00000088013.5
Myrf
myelin regulatory factor
chr2_+_156840077 3.686 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr6_+_114131229 3.672 ENSMUST00000032451.7
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr7_-_30973464 3.630 ENSMUST00000001279.8
Lsr
lipolysis stimulated lipoprotein receptor
chr5_-_52566264 3.589 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr10_-_5805412 3.507 ENSMUST00000019907.7
Fbxo5
F-box protein 5
chr11_+_69632927 3.468 ENSMUST00000018909.3
Fxr2
fragile X mental retardation, autosomal homolog 2
chr18_+_60925612 3.451 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr11_-_82871133 3.443 ENSMUST00000071152.7
ENSMUST00000108173.3
Rffl

ring finger and FYVE like domain containing protein

chr2_+_109280738 3.417 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr9_-_106158109 3.348 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr6_-_115251839 3.322 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr11_-_109472611 3.302 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr4_+_148160613 3.295 ENSMUST00000047951.8
Fbxo2
F-box protein 2
chr10_-_80399478 3.269 ENSMUST00000092295.3
ENSMUST00000105349.1
Mbd3

methyl-CpG binding domain protein 3

chr12_+_84009481 3.239 ENSMUST00000168120.1
Acot1
acyl-CoA thioesterase 1
chr11_+_121702591 3.170 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr2_+_32535315 3.150 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A

chr16_+_64851991 3.139 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr14_+_122534305 3.133 ENSMUST00000154206.1
ENSMUST00000038374.6
ENSMUST00000135578.1
Pcca


propionyl-Coenzyme A carboxylase, alpha polypeptide


chr4_+_41762309 3.111 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr11_+_85832551 3.110 ENSMUST00000000095.6
Tbx2
T-box 2
chr10_-_77089428 3.072 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr14_+_28511344 3.045 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr12_+_8771405 3.019 ENSMUST00000171158.1
Sdc1
syndecan 1
chr15_-_89355655 2.995 ENSMUST00000023283.5
Lmf2
lipase maturation factor 2
chr14_-_8666236 2.993 ENSMUST00000102996.3
4930452B06Rik
RIKEN cDNA 4930452B06 gene
chr11_+_114765363 2.922 ENSMUST00000138804.1
ENSMUST00000084368.5
Kif19a

kinesin family member 19A

chr8_-_87959560 2.900 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr11_-_69948145 2.890 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr3_+_87906321 2.872 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr4_-_135873801 2.855 ENSMUST00000030436.5
Pnrc2
proline-rich nuclear receptor coactivator 2
chr7_-_93081027 2.845 ENSMUST00000098303.1
Gm9934
predicted gene 9934
chr19_-_12765447 2.809 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr19_+_46305682 2.760 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chrX_-_7967817 2.722 ENSMUST00000033502.7
Gata1
GATA binding protein 1
chr1_+_75450436 2.722 ENSMUST00000113577.1
Asic4
acid-sensing (proton-gated) ion channel family member 4
chr8_+_85840971 2.719 ENSMUST00000053771.7
ENSMUST00000161850.1
Phkb

phosphorylase kinase beta

chr11_+_70657196 2.690 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chr4_-_57143437 2.660 ENSMUST00000095076.3
ENSMUST00000030142.3
Epb4.1l4b

erythrocyte protein band 4.1-like 4b

chr13_+_49187485 2.625 ENSMUST00000049022.8
ENSMUST00000120733.1
Ninj1

ninjurin 1

chr15_-_75909319 2.604 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr7_+_73391160 2.585 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr15_+_99702278 2.526 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chrX_+_71050160 2.518 ENSMUST00000082088.3
ENSMUST00000114629.3
Mamld1

mastermind-like domain containing 1

chr7_+_16843049 2.518 ENSMUST00000086104.4
Prkd2
protein kinase D2
chr11_+_70657687 2.493 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr2_+_27709247 2.463 ENSMUST00000100251.2
Rxra
retinoid X receptor alpha
chr11_+_114851814 2.450 ENSMUST00000053361.5
ENSMUST00000021071.7
ENSMUST00000136785.1
Gprc5c


G protein-coupled receptor, family C, group 5, member C


chr15_-_75909289 2.434 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr6_+_120666388 2.369 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr11_-_102897146 2.363 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr12_+_8771317 2.362 ENSMUST00000020911.7
Sdc1
syndecan 1
chr1_+_92831614 2.353 ENSMUST00000045970.6
Gpc1
glypican 1
chr10_-_127666598 2.349 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr10_-_13193096 2.328 ENSMUST00000019950.4
Ltv1
LTV1 homolog (S. cerevisiae)
chr9_+_114978507 2.319 ENSMUST00000183104.1
Osbpl10
oxysterol binding protein-like 10
chr11_-_70656467 2.271 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr9_-_110742577 2.262 ENSMUST00000006005.7
Pth1r
parathyroid hormone 1 receptor
chr8_+_105170668 2.262 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta



chr1_-_182282738 2.189 ENSMUST00000035295.5
Degs1
degenerative spermatocyte homolog 1 (Drosophila)
chr5_+_139423151 2.176 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr11_+_60537978 2.144 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr14_+_55854115 2.140 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr12_-_103242143 2.129 ENSMUST00000074416.3
Prima1
proline rich membrane anchor 1
chr17_-_24696147 2.126 ENSMUST00000046839.8
Gfer
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr18_+_60925644 2.125 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr11_-_102407315 1.971 ENSMUST00000149777.1
ENSMUST00000154001.1
Slc25a39

solute carrier family 25, member 39

chr11_-_72796028 1.955 ENSMUST00000156294.1
Cyb5d2
cytochrome b5 domain containing 2
chr1_-_106714217 1.927 ENSMUST00000112751.1
Bcl2
B cell leukemia/lymphoma 2
chr14_-_30923547 1.899 ENSMUST00000170415.1
Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr7_+_16842896 1.893 ENSMUST00000168093.2
Prkd2
protein kinase D2
chr4_-_57956283 1.887 ENSMUST00000030051.5
Txn1
thioredoxin 1
chr7_-_127930066 1.874 ENSMUST00000032988.8
Prss8
protease, serine, 8 (prostasin)
chr17_+_34898931 1.860 ENSMUST00000097342.3
ENSMUST00000013931.5
Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr17_-_25868727 1.830 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr15_+_89355730 1.808 ENSMUST00000074552.5
ENSMUST00000088717.6
Ncaph2

non-SMC condensin II complex, subunit H2

chr9_-_51077064 1.771 ENSMUST00000098782.3
Layn
layilin
chr11_-_102407455 1.768 ENSMUST00000107098.1
ENSMUST00000018821.2
Slc25a39

solute carrier family 25, member 39

chr11_+_114851507 1.767 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr6_+_43265582 1.766 ENSMUST00000031750.7
Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chr12_-_79296266 1.754 ENSMUST00000021547.6
Zfyve26
zinc finger, FYVE domain containing 26
chrX_-_51205990 1.731 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr15_-_36608959 1.726 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr1_-_75506331 1.723 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1

obscurin-like 1

chr12_-_104865076 1.721 ENSMUST00000109937.1
ENSMUST00000109936.1
Clmn

calmin

chr7_-_63938862 1.705 ENSMUST00000063694.8
Klf13
Kruppel-like factor 13
chr5_+_143403819 1.692 ENSMUST00000110731.2
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr10_+_99263224 1.679 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr11_-_72795801 1.672 ENSMUST00000079681.5
Cyb5d2
cytochrome b5 domain containing 2
chr1_-_186705980 1.661 ENSMUST00000045288.8
Tgfb2
transforming growth factor, beta 2
chr2_-_65238625 1.660 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
Cobll1


Cobl-like 1


chr7_-_142657466 1.656 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr16_+_20673517 1.634 ENSMUST00000115460.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr15_+_89355716 1.632 ENSMUST00000036987.5
Ncaph2
non-SMC condensin II complex, subunit H2
chr8_+_123477859 1.622 ENSMUST00000001520.7
Afg3l1
AFG3(ATPase family gene 3)-like 1 (yeast)
chr17_-_46705002 1.619 ENSMUST00000002839.8
Ppp2r5d
protein phosphatase 2, regulatory subunit B (B56), delta isoform
chr1_+_135818593 1.609 ENSMUST00000038760.8
Lad1
ladinin
chr11_-_69579320 1.591 ENSMUST00000048139.5
Wrap53
WD repeat containing, antisense to Trp53
chr8_+_114205590 1.579 ENSMUST00000049509.6
ENSMUST00000150963.1
Vat1l

vesicle amine transport protein 1 homolog-like (T. californica)

chr10_+_96616998 1.567 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chrX_+_161162994 1.559 ENSMUST00000077375.4
Scml2
sex comb on midleg-like 2 (Drosophila)
chr5_+_64160207 1.547 ENSMUST00000101195.2
Tbc1d1
TBC1 domain family, member 1
chr11_+_75655873 1.539 ENSMUST00000108431.2
Myo1c
myosin IC
chr15_-_64312636 1.534 ENSMUST00000177083.1
ENSMUST00000177371.1
Asap1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1

chr2_+_30416031 1.514 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr9_-_45936049 1.494 ENSMUST00000034590.2
Tagln
transgelin
chrX_+_56963325 1.464 ENSMUST00000096431.3
Gpr112
G protein-coupled receptor 112
chr13_-_43560174 1.449 ENSMUST00000021800.4
Mcur1
mitochondrial calcium uniporter regulator 1
chr9_+_58134535 1.421 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr3_+_129213920 1.397 ENSMUST00000042587.10
Pitx2
paired-like homeodomain transcription factor 2
chr2_-_3419066 1.393 ENSMUST00000115082.3
Meig1
meiosis expressed gene 1
chr2_-_30093642 1.390 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr2_-_3419019 1.384 ENSMUST00000115084.1
ENSMUST00000115083.1
Meig1

meiosis expressed gene 1

chr3_+_94377432 1.370 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr7_-_133122615 1.339 ENSMUST00000167218.1
Ctbp2
C-terminal binding protein 2
chr3_+_94377505 1.322 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr12_+_71016658 1.311 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr7_-_92874196 1.295 ENSMUST00000032877.9
4632434I11Rik
RIKEN cDNA 4632434I11 gene
chr16_+_17646564 1.294 ENSMUST00000182117.1
ENSMUST00000182671.1
ENSMUST00000182344.1
Ccdc74a


coiled-coil domain containing 74A


chr11_-_69695521 1.286 ENSMUST00000181261.1
Tnfsf12
tumor necrosis factor (ligand) superfamily, member 12
chr5_+_110653444 1.278 ENSMUST00000031478.5
Ddx51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr15_-_50890396 1.273 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chrX_+_16619698 1.261 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chrM_-_14060 1.246 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr7_+_110627650 1.238 ENSMUST00000033054.8
Adm
adrenomedullin
chr9_+_119937606 1.234 ENSMUST00000035100.5
Ttc21a
tetratricopeptide repeat domain 21A
chrX_-_73921917 1.231 ENSMUST00000114389.3
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr2_+_30416096 1.220 ENSMUST00000113601.3
ENSMUST00000113603.3
Ppp2r4

protein phosphatase 2A, regulatory subunit B (PR 53)

chr2_-_119477613 1.220 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr17_+_15704963 1.218 ENSMUST00000024627.7
ENSMUST00000173311.1
Chd1

chromodomain helicase DNA binding protein 1

chr17_+_46646225 1.177 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr1_-_82291370 1.160 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr6_-_28397999 1.147 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chr5_-_101665195 1.115 ENSMUST00000044125.8
Nkx6-1
NK6 homeobox 1
chr17_+_34898463 1.107 ENSMUST00000114033.2
ENSMUST00000078061.6
Ehmt2

euchromatic histone lysine N-methyltransferase 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
3.7 11.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
3.5 10.5 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
3.4 10.3 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
2.8 8.5 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
2.6 15.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
2.2 13.4 GO:0060242 contact inhibition(GO:0060242)
1.9 5.6 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
1.9 29.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.8 7.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.8 8.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.7 11.6 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.6 4.9 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
1.6 6.4 GO:0046836 glycolipid transport(GO:0046836)
1.6 9.6 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.5 4.6 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.5 4.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.5 5.8 GO:0006842 tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746)
1.4 7.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
1.4 5.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
1.4 6.8 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
1.2 6.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.2 3.6 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.2 1.2 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
1.1 4.5 GO:0032439 endosome localization(GO:0032439)
1.1 4.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.1 5.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.1 3.2 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
1.0 3.1 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
1.0 10.3 GO:0042473 outer ear morphogenesis(GO:0042473)
1.0 3.0 GO:0036166 phenotypic switching(GO:0036166)
1.0 6.9 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.9 4.7 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.9 3.7 GO:2000054 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.9 4.4 GO:0089700 positive regulation of T cell receptor signaling pathway(GO:0050862) protein kinase D signaling(GO:0089700)
0.9 3.5 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.9 3.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.8 1.7 GO:1903224 regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.8 1.7 GO:0048818 positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795)
0.8 2.4 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.8 5.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.8 8.5 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.7 5.2 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.7 2.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706) regulation of vascular smooth muscle cell differentiation(GO:1905063) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.7 4.2 GO:0030916 otic vesicle formation(GO:0030916)
0.7 10.9 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.7 3.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.6 3.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.6 3.0 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.6 1.8 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.6 5.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.6 5.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.5 1.6 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.5 2.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.5 1.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.5 2.1 GO:1904426 positive regulation of GTP binding(GO:1904426) regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.5 1.5 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.5 2.5 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.5 2.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.4 17.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.4 1.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.4 3.7 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.4 2.7 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.4 4.6 GO:0042711 maternal behavior(GO:0042711)
0.4 2.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.3 1.4 GO:0060459 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3 5.6 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.3 1.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 2.4 GO:0001842 neural fold formation(GO:0001842)
0.3 2.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 1.0 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.3 4.3 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.3 2.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.3 1.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.3 11.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.3 1.6 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.3 4.1 GO:0051451 myoblast migration(GO:0051451)
0.3 9.7 GO:0009299 mRNA transcription(GO:0009299)
0.3 1.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.3 9.2 GO:0006270 DNA replication initiation(GO:0006270)
0.3 2.1 GO:0097421 liver regeneration(GO:0097421)
0.3 1.4 GO:0046864 retinol transport(GO:0034633) nose morphogenesis(GO:0043585) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.3 4.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.3 1.9 GO:0000103 sulfate assimilation(GO:0000103)
0.3 2.1 GO:0015074 DNA integration(GO:0015074)
0.3 3.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.3 3.1 GO:0046697 decidualization(GO:0046697)
0.3 2.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.3 4.0 GO:0009109 coenzyme catabolic process(GO:0009109)
0.2 3.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 1.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 3.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.2 0.5 GO:0016115 terpenoid catabolic process(GO:0016115)
0.2 4.0 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.2 3.1 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.2 1.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 2.8 GO:0002467 germinal center formation(GO:0002467)
0.2 1.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 1.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 1.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 3.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2 3.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 1.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.6 GO:0072338 creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492) cellular lactam metabolic process(GO:0072338)
0.2 1.7 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.9 GO:0070633 transepithelial transport(GO:0070633)
0.2 2.6 GO:0060033 anatomical structure regression(GO:0060033)
0.2 0.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 1.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 1.4 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.2 0.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 1.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.4 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.8 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.9 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 0.6 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 1.2 GO:2001214 negative regulation of vascular permeability(GO:0043116) positive regulation of vasculogenesis(GO:2001214)
0.1 2.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 3.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 3.7 GO:0030261 chromosome condensation(GO:0030261)
0.1 3.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 2.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 2.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 4.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.3 GO:0045414 regulation of interleukin-8 biosynthetic process(GO:0045414)
0.1 1.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 2.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 8.1 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.1 2.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 2.2 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 1.1 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 2.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 3.2 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.0 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.6 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.7 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 2.6 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 1.8 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.0 1.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 2.1 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 1.1 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.8 GO:0006821 chloride transport(GO:0006821)
0.0 0.4 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.0 0.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 1.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.8 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.0 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) positive regulation of superoxide dismutase activity(GO:1901671) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) glyoxal catabolic process(GO:1903190) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of removal of superoxide radicals(GO:1904833) positive regulation of cellular amino acid biosynthetic process(GO:2000284) positive regulation of androgen receptor activity(GO:2000825)
0.0 1.0 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0099625 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.0 1.2 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.6 GO:0002224 toll-like receptor signaling pathway(GO:0002224)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 17.8 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
4.9 14.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.6 9.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.5 4.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.5 4.4 GO:0005588 collagen type V trimer(GO:0005588)
1.1 5.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.0 5.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.9 2.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.8 7.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.6 9.2 GO:0042555 MCM complex(GO:0042555)
0.6 3.6 GO:0061689 tricellular tight junction(GO:0061689)
0.6 2.4 GO:0090537 CERF complex(GO:0090537)
0.6 2.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.5 2.1 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.5 1.5 GO:0045160 myosin I complex(GO:0045160)
0.5 3.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.4 1.6 GO:0005745 m-AAA complex(GO:0005745)
0.4 2.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 2.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 1.2 GO:0005899 insulin receptor complex(GO:0005899)
0.4 12.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 3.0 GO:0031415 NatA complex(GO:0031415)
0.3 4.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 4.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 2.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 11.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 0.7 GO:0000814 ESCRT II complex(GO:0000814)
0.2 2.7 GO:0097470 ribbon synapse(GO:0097470)
0.2 1.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 5.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 3.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.9 GO:0046930 pore complex(GO:0046930)
0.1 3.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 5.6 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.5 GO:0071564 npBAF complex(GO:0071564)
0.1 1.4 GO:0034464 BBSome(GO:0034464)
0.1 2.9 GO:0005771 multivesicular body(GO:0005771)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.2 GO:0031011 Ino80 complex(GO:0031011)
0.1 39.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 4.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.0 GO:0032039 integrator complex(GO:0032039)
0.1 21.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 1.1 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 4.0 GO:0031012 extracellular matrix(GO:0031012)
0.1 3.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 3.5 GO:0005844 polysome(GO:0005844)
0.1 2.9 GO:0005871 kinesin complex(GO:0005871)
0.1 0.8 GO:0005839 proteasome core complex(GO:0005839)
0.1 3.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 4.9 GO:0005903 brush border(GO:0005903)
0.0 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 1.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.9 GO:0005884 actin filament(GO:0005884)
0.0 4.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0043235 receptor complex(GO:0043235)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.7 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 1.9 GO:0045177 apical part of cell(GO:0045177)
0.0 2.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 17.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
3.7 11.0 GO:0004962 endothelin receptor activity(GO:0004962)
2.6 10.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
2.1 6.4 GO:0017089 glycolipid transporter activity(GO:0017089)
2.1 6.2 GO:0005534 galactose binding(GO:0005534)
1.9 5.8 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
1.4 4.2 GO:0005118 sevenless binding(GO:0005118)
1.3 29.7 GO:0070410 co-SMAD binding(GO:0070410)
1.3 4.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
1.3 3.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
1.2 3.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.1 6.9 GO:0015265 urea channel activity(GO:0015265)
1.0 3.1 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
1.0 3.0 GO:0005110 frizzled-2 binding(GO:0005110)
1.0 23.3 GO:0070064 proline-rich region binding(GO:0070064)
1.0 5.8 GO:0019841 retinol binding(GO:0019841)
0.8 2.4 GO:0070052 collagen V binding(GO:0070052)
0.8 3.1 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.7 2.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.7 2.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.7 2.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.7 10.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.7 2.7 GO:0008142 oxysterol binding(GO:0008142)
0.6 3.0 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.6 4.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.6 5.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 2.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.5 2.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.5 2.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.5 3.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 1.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.4 6.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 1.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 2.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.4 2.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 1.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.4 1.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.3 9.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 1.3 GO:0051378 serotonin binding(GO:0051378)
0.3 2.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 4.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 3.7 GO:0070411 I-SMAD binding(GO:0070411)
0.3 2.1 GO:0043495 protein anchor(GO:0043495)
0.3 11.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 3.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.9 GO:0051434 BH3 domain binding(GO:0051434)
0.2 4.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 3.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 3.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 5.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 2.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 1.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 4.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 0.5 GO:0043426 MRF binding(GO:0043426)
0.2 1.9 GO:0005522 profilin binding(GO:0005522)
0.2 9.7 GO:0003678 DNA helicase activity(GO:0003678)
0.1 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 3.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 18.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 2.3 GO:0008143 poly(A) binding(GO:0008143)
0.1 8.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 2.7 GO:0005272 sodium channel activity(GO:0005272)
0.1 3.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 2.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 4.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 5.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 5.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 5.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 4.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 2.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 3.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 4.3 GO:0001047 core promoter binding(GO:0001047)
0.1 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 7.3 GO:0030165 PDZ domain binding(GO:0030165)
0.1 6.9 GO:0001948 glycoprotein binding(GO:0001948)
0.1 1.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 4.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 3.4 GO:0002020 protease binding(GO:0002020)
0.0 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 30.6 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.6 GO:0008083 growth factor activity(GO:0008083)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 1.3 GO:0005125 cytokine activity(GO:0005125)
0.0 4.5 GO:0003729 mRNA binding(GO:0003729)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.3 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.7 GO:0004930 G-protein coupled receptor activity(GO:0004930)