Motif ID: Lef1
Z-value: 1.630

Transcription factors associated with Lef1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Lef1 | ENSMUSG00000027985.8 | Lef1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Lef1 | mm10_v2_chr3_+_131110350_131110471 | 0.45 | 8.5e-05 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 153 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.6 | 39.4 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
2.3 | 36.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
3.6 | 28.4 | GO:0048625 | myoblast fate commitment(GO:0048625) |
2.4 | 26.0 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
1.0 | 24.1 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
0.8 | 17.6 | GO:0001967 | suckling behavior(GO:0001967) |
5.8 | 17.5 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
4.3 | 17.3 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
4.2 | 16.7 | GO:2000054 | negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054) |
0.1 | 13.9 | GO:0030326 | embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113) |
1.3 | 13.3 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
1.1 | 13.1 | GO:0048853 | forebrain morphogenesis(GO:0048853) |
0.1 | 12.8 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
4.2 | 12.7 | GO:0021893 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) |
1.7 | 11.9 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
1.7 | 11.6 | GO:0000022 | mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256) |
0.4 | 11.3 | GO:0009409 | response to cold(GO:0009409) |
3.6 | 10.8 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
0.1 | 10.8 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
0.4 | 10.5 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 59 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 134.4 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 90.7 | GO:0005634 | nucleus(GO:0005634) |
3.2 | 28.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.0 | 17.5 | GO:0005730 | nucleolus(GO:0005730) |
1.0 | 17.3 | GO:0043205 | fibril(GO:0043205) |
0.3 | 17.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.6 | 14.8 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.6 | 13.6 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.5 | 13.3 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
2.0 | 10.2 | GO:0008623 | CHRAC(GO:0008623) |
0.1 | 9.5 | GO:0072686 | mitotic spindle(GO:0072686) |
2.8 | 8.4 | GO:0042585 | germinal vesicle(GO:0042585) |
0.5 | 7.5 | GO:0005614 | interstitial matrix(GO:0005614) |
1.2 | 7.4 | GO:0000235 | astral microtubule(GO:0000235) |
1.8 | 7.3 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.1 | 7.2 | GO:0005871 | kinesin complex(GO:0005871) |
0.5 | 5.8 | GO:0031105 | septin complex(GO:0031105) |
0.3 | 5.6 | GO:0016580 | Sin3 complex(GO:0016580) |
0.9 | 5.2 | GO:0044294 | dendritic growth cone(GO:0044294) |
2.5 | 5.0 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 94 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 115.8 | GO:0044212 | transcription regulatory region DNA binding(GO:0044212) |
0.1 | 56.9 | GO:0003677 | DNA binding(GO:0003677) |
1.8 | 50.2 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.2 | 31.0 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.2 | 23.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.4 | 19.3 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
1.2 | 18.7 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
5.8 | 17.5 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
3.5 | 17.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
1.9 | 15.3 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.5 | 13.9 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.3 | 13.3 | GO:0004407 | histone deacetylase activity(GO:0004407) |
0.5 | 12.8 | GO:0001968 | fibronectin binding(GO:0001968) |
0.7 | 11.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.2 | 8.9 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.8 | 8.1 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.3 | 8.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.6 | 7.9 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.0 | 7.9 | GO:0051015 | actin filament binding(GO:0051015) |
0.6 | 7.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |