Motif ID: Lhx3

Z-value: 0.674


Transcription factors associated with Lhx3:

Gene SymbolEntrez IDGene Name
Lhx3 ENSMUSG00000026934.9 Lhx3



Activity profile for motif Lhx3.

activity profile for motif Lhx3


Sorted Z-values histogram for motif Lhx3

Sorted Z-values for motif Lhx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Lhx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 84 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_45103747 5.903 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr4_+_136143497 5.872 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr7_-_103827922 4.465 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr4_-_14621805 3.898 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr13_+_49608030 3.777 ENSMUST00000021822.5
 Ogn
osteoglycin
chr17_-_67950908 3.644 ENSMUST00000164647.1
 Arhgap28
Rho GTPase activating protein 28
chr3_+_122419772 3.052 ENSMUST00000029766.4
 Bcar3
breast cancer anti-estrogen resistance 3
chr4_+_102589687 2.899 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chr13_-_101692624 2.327 ENSMUST00000035532.6
 Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr3_+_151437887 2.273 ENSMUST00000046977.7
 Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr10_-_64090265 2.271 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr11_+_109543694 2.245 ENSMUST00000106696.1
 Arsg
arylsulfatase G
chr5_-_70842617 2.172 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr2_-_84425258 2.168 ENSMUST00000074262.2
 Calcrl
calcitonin receptor-like
chr2_-_33087169 2.124 ENSMUST00000102810.3
 Garnl3
GTPase activating RANGAP domain-like 3
chr2_-_33086366 2.047 ENSMUST00000049618.2
 Garnl3
GTPase activating RANGAP domain-like 3
chr4_-_14621669 1.884 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr2_+_125136692 1.849 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr4_-_14621494 1.845 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr14_+_80000292 1.781 ENSMUST00000088735.3
 Olfm4
olfactomedin 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 7.6 GO:0019532 oxalate transport(GO:0019532)
0.2 5.9 GO:0071398 cellular response to fatty acid(GO:0071398)
0.1 5.7 GO:0019882 antigen processing and presentation(GO:0019882)
0.3 3.9 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.9 3.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 2.9 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 2.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.5 2.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 2.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 1.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.6 GO:0042742 defense response to bacterium(GO:0042742)
0.1 1.5 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.5 1.4 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.3 1.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 1.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 1.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 5.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
1.1 4.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 4.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.8 GO:0042581 specific granule(GO:0042581)
0.0 1.8 GO:0016607 nuclear speck(GO:0016607)
0.0 1.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.4 1.3 GO:0032437 cuticular plate(GO:0032437)
0.3 1.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.2 GO:0071564 npBAF complex(GO:0071564)
0.1 1.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 7.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
2.0 5.9 GO:0019770 IgG receptor activity(GO:0019770)
0.1 4.6 GO:0005504 fatty acid binding(GO:0005504)
1.1 4.5 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.0 3.8 GO:0008083 growth factor activity(GO:0008083)
0.0 3.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 3.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 2.9 GO:0030552 cAMP binding(GO:0030552)
0.6 2.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.5 2.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 2.2 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.1 2.2 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.1 2.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 1.4 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.3 1.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 1.3 GO:0030506 ankyrin binding(GO:0030506)