Motif ID: Mafa

Z-value: 1.334


Transcription factors associated with Mafa:

Gene SymbolEntrez IDGene Name
Mafa ENSMUSG00000047591.4 Mafa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafamm10_v2_chr15_-_75747922_757479220.038.2e-01Click!


Activity profile for motif Mafa.

activity profile for motif Mafa


Sorted Z-values histogram for motif Mafa

Sorted Z-values for motif Mafa



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafa

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 86 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_98032983 22.026 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr9_-_98033181 21.724 ENSMUST00000035027.6
Clstn2
calsyntenin 2
chr16_-_17576631 19.798 ENSMUST00000164545.1
ENSMUST00000164490.1
ENSMUST00000172164.1
Slc7a4


solute carrier family 7 (cationic amino acid transporter, y+ system), member 4


chrX_-_73869804 16.909 ENSMUST00000066576.5
ENSMUST00000114430.1
L1cam

L1 cell adhesion molecule

chr1_-_169747634 16.495 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr14_+_119138415 15.731 ENSMUST00000065904.3
Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr1_-_136260873 15.282 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr8_-_70487314 14.147 ENSMUST00000045286.7
Tmem59l
transmembrane protein 59-like
chr16_-_74411292 13.871 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr7_+_54835959 12.984 ENSMUST00000082373.6
Luzp2
leucine zipper protein 2
chr12_+_3365108 12.239 ENSMUST00000020999.5
Kif3c
kinesin family member 3C
chr10_+_58813359 12.135 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr16_-_74411776 11.650 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr11_-_66525795 10.987 ENSMUST00000123454.1
Shisa6
shisa homolog 6 (Xenopus laevis)
chr4_+_102254993 10.812 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr10_-_84440591 10.247 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr5_+_111417263 10.093 ENSMUST00000094463.4
Mn1
meningioma 1
chr1_-_38836090 10.040 ENSMUST00000147695.1
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr14_+_64588112 10.027 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr4_+_43406435 9.512 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 43.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
8.5 25.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 19.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
1.5 19.6 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
1.0 18.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.7 16.9 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
2.6 15.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 14.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2 12.2 GO:0072384 organelle transport along microtubule(GO:0072384)
0.7 10.7 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.1 10.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
1.4 10.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
2.0 9.9 GO:0034436 glycoprotein transport(GO:0034436)
0.9 9.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.7 9.1 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.8 8.3 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.1 8.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.5 5.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.7 5.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
1.2 4.9 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 43.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.8 25.5 GO:0030673 axolemma(GO:0030673)
0.9 19.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 19.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.4 18.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 16.5 GO:0044295 axonal growth cone(GO:0044295)
1.0 12.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
1.3 10.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.8 9.9 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 9.1 GO:0008180 COP9 signalosome(GO:0008180)
0.9 8.3 GO:0005883 neurofilament(GO:0005883)
0.0 8.1 GO:0005874 microtubule(GO:0005874)
0.0 6.5 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 4.9 GO:0043679 axon terminus(GO:0043679)
0.1 4.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.4 3.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 2.7 GO:0000242 pericentriolar material(GO:0000242)
0.8 2.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 2.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 27.5 GO:0005509 calcium ion binding(GO:0005509)
2.8 25.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 22.0 GO:0015297 antiporter activity(GO:0015297)
0.5 19.6 GO:0030552 cAMP binding(GO:0030552)
3.4 16.9 GO:0033691 sialic acid binding(GO:0033691)
0.4 16.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.5 15.7 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 13.7 GO:0008270 zinc ion binding(GO:0008270)
0.1 12.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 11.8 GO:0019894 kinesin binding(GO:0019894)
0.0 10.7 GO:0008134 transcription factor binding(GO:0008134)
0.1 10.2 GO:0002039 p53 binding(GO:0002039)
3.3 9.9 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.0 7.3 GO:0000287 magnesium ion binding(GO:0000287)
1.5 6.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 5.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 5.3 GO:0005543 phospholipid binding(GO:0005543)
0.4 5.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
1.2 4.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.5 4.9 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)