Motif ID: Mafb

Z-value: 0.599


Transcription factors associated with Mafb:

Gene SymbolEntrez IDGene Name
Mafb ENSMUSG00000074622.3 Mafb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafbmm10_v2_chr2_-_160367057_1603670730.491.7e-05Click!


Activity profile for motif Mafb.

activity profile for motif Mafb


Sorted Z-values histogram for motif Mafb

Sorted Z-values for motif Mafb



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_170731807 4.730 ENSMUST00000029075.4
 Dok5
docking protein 5
chr7_+_130936172 4.374 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr18_+_65873478 3.920 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr19_-_5510467 3.819 ENSMUST00000070172.4
 Snx32
sorting nexin 32
chr7_-_120202104 3.771 ENSMUST00000033198.5
 Crym
crystallin, mu
chr10_+_40349265 3.449 ENSMUST00000044672.4
ENSMUST00000095743.2
 Cdk19

cyclin-dependent kinase 19

chr15_+_82252397 3.421 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr19_+_26753588 3.278 ENSMUST00000177116.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_168741898 3.170 ENSMUST00000109176.1
ENSMUST00000178504.1
 Atp9a

ATPase, class II, type 9A

chr9_-_18473559 2.892 ENSMUST00000034647.4
 Zfp558
zinc finger protein 558
chr17_+_3532554 2.874 ENSMUST00000168560.1
 Cldn20
claudin 20
chr6_+_120773633 2.796 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr4_+_102421518 2.748 ENSMUST00000106904.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr4_-_136886187 2.646 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr11_+_75531690 2.554 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
 Slc43a2



solute carrier family 43, member 2



chr7_-_141010759 2.525 ENSMUST00000026565.6
 Ifitm3
interferon induced transmembrane protein 3
chr6_+_124997062 2.469 ENSMUST00000159391.1
 Pianp
PILR alpha associated neural protein
chr2_-_127482499 2.296 ENSMUST00000088538.5
 Kcnip3
Kv channel interacting protein 3, calsenilin
chr12_-_24493656 2.293 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr1_-_136260873 2.223 ENSMUST00000086395.5
 Gpr25
G protein-coupled receptor 25

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 112 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.0 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.4 4.7 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.7 4.4 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.8 4.2 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 4.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 3.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.8 3.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 3.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.4 3.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 3.2 GO:0006334 nucleosome assembly(GO:0006334)
0.1 2.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 2.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 2.6 GO:0001542 ovulation from ovarian follicle(GO:0001542) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 2.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 2.3 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.1 2.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 2.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 2.2 GO:0015807 L-amino acid transport(GO:0015807)
0.0 2.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.2 GO:0005802 trans-Golgi network(GO:0005802)
0.1 4.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 3.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 3.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 3.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.2 2.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 2.5 GO:0071564 npBAF complex(GO:0071564)
0.0 2.5 GO:0016605 PML body(GO:0016605)
0.1 2.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 2.1 GO:0097228 sperm principal piece(GO:0097228)
0.1 2.0 GO:0042581 specific granule(GO:0042581)
0.3 1.9 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.7 GO:0005771 multivesicular body(GO:0005771)
0.0 1.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 4.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 4.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 3.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.5 3.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 3.6 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 3.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 3.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 2.7 GO:0030552 cAMP binding(GO:0030552)
0.9 2.6 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 2.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.3 2.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 2.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 2.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.4 2.0 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 2.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 2.0 GO:0045296 cadherin binding(GO:0045296)