Motif ID: Maff

Z-value: 0.649


Transcription factors associated with Maff:

Gene SymbolEntrez IDGene Name
Maff ENSMUSG00000042622.7 Maff

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Maffmm10_v2_chr15_+_79348061_793481540.482.5e-05Click!


Activity profile for motif Maff.

activity profile for motif Maff


Sorted Z-values histogram for motif Maff

Sorted Z-values for motif Maff



Network of associatons between targets according to the STRING database.



First level regulatory network of Maff

PNG image of the network

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Top targets:


Showing 1 to 20 of 68 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_3270767 6.049 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr16_-_22439719 5.789 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr13_-_23710714 4.662 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
 Hfe


hemochromatosis


chr4_-_136886187 4.569 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr17_-_25570678 4.509 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr14_+_118787894 3.831 ENSMUST00000047761.6
ENSMUST00000071546.7
 Cldn10

claudin 10

chr7_-_110862944 3.631 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr4_-_143299463 2.945 ENSMUST00000119654.1
 Pdpn
podoplanin
chr4_-_143299498 2.874 ENSMUST00000030317.7
 Pdpn
podoplanin
chr11_-_109473598 2.788 ENSMUST00000070152.5
 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr13_+_48261427 2.598 ENSMUST00000021810.1
 Id4
inhibitor of DNA binding 4
chr5_+_104435112 2.239 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
 Spp1





secreted phosphoprotein 1





chr1_+_136018062 2.154 ENSMUST00000117950.1
 Tmem9
transmembrane protein 9
chr1_+_136017967 2.147 ENSMUST00000063719.8
ENSMUST00000118832.1
 Tmem9

transmembrane protein 9

chr1_-_120074023 1.879 ENSMUST00000056089.7
 Tmem37
transmembrane protein 37
chr5_-_135251209 1.854 ENSMUST00000062572.2
 Fzd9
frizzled homolog 9 (Drosophila)
chr4_+_102421518 1.841 ENSMUST00000106904.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr2_-_130397525 1.756 ENSMUST00000028897.7
 Cpxm1
carboxypeptidase X 1 (M14 family)
chr18_+_4921662 1.714 ENSMUST00000143254.1
 Svil
supervillin
chr7_+_84528964 1.675 ENSMUST00000180387.1
 Gm2115
predicted gene 2115

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 6.0 GO:0001887 selenium compound metabolic process(GO:0001887)
1.2 5.8 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.6 5.8 GO:0010572 positive regulation of platelet activation(GO:0010572)
1.6 4.7 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.2 4.6 GO:0006958 complement activation, classical pathway(GO:0006958)
1.5 4.5 GO:0072034 renal vesicle induction(GO:0072034)
0.5 3.6 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 2.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 2.7 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.6 2.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 2.2 GO:0033280 response to vitamin D(GO:0033280)
0.0 1.9 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.9 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.5 1.6 GO:1900133 renin secretion into blood stream(GO:0002001) negative regulation of urine volume(GO:0035811) regulation of renin secretion into blood stream(GO:1900133)
0.5 1.5 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 1.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 1.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 1.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.2 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2 1.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.3 GO:0005615 extracellular space(GO:0005615)
0.0 5.8 GO:0001726 ruffle(GO:0001726)
0.9 4.7 GO:1990357 terminal web(GO:1990357)
0.1 4.6 GO:0005581 collagen trimer(GO:0005581)
0.0 4.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 3.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.4 GO:0005770 late endosome(GO:0005770)
0.1 1.9 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.7 GO:0043034 costamere(GO:0043034)
0.0 1.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 1.0 GO:0045160 myosin I complex(GO:0045160)
0.2 1.0 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.0 GO:0005916 fascia adherens(GO:0005916)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.3 0.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.0 GO:0008430 selenium binding(GO:0008430)
0.5 5.8 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.5 4.7 GO:0039706 co-receptor binding(GO:0039706)
0.0 4.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 3.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 2.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.8 GO:0030552 cAMP binding(GO:0030552)
0.1 1.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 1.6 GO:0051379 epinephrine binding(GO:0051379)
0.0 1.6 GO:0015293 symporter activity(GO:0015293)
0.4 1.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.2 GO:0005522 profilin binding(GO:0005522)
0.2 1.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)