Motif ID: Maz_Zfp281

Z-value: 1.710

Transcription factors associated with Maz_Zfp281:

Gene SymbolEntrez IDGene Name
Maz ENSMUSG00000030678.6 Maz
Zfp281 ENSMUSG00000041483.8 Zfp281

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mazmm10_v2_chr7_-_127026479_1270264960.532.6e-06Click!
Zfp281mm10_v2_chr1_+_136624901_1366249490.019.3e-01Click!


Activity profile for motif Maz_Zfp281.

activity profile for motif Maz_Zfp281


Sorted Z-values histogram for motif Maz_Zfp281

Sorted Z-values for motif Maz_Zfp281



Network of associatons between targets according to the STRING database.



First level regulatory network of Maz_Zfp281

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_84774123 24.008 ENSMUST00000114195.1
 Jam2
junction adhesion molecule 2
chr7_-_144939823 23.592 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr8_+_12395287 23.147 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chr4_+_154960915 21.867 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr10_-_127341583 21.509 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr17_+_85620816 19.616 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr7_+_19094594 19.203 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr11_-_88718165 18.285 ENSMUST00000107908.1
 Msi2
musashi RNA-binding protein 2
chr10_-_120476469 18.170 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr14_-_98169542 17.928 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chr5_+_108694222 17.824 ENSMUST00000013633.8
ENSMUST00000112560.3
 Fgfrl1

fibroblast growth factor receptor-like 1

chr17_+_85613432 16.952 ENSMUST00000176081.1
 Six3
sine oculis-related homeobox 3
chr14_-_52316323 16.821 ENSMUST00000135523.1
 Sall2
sal-like 2 (Drosophila)
chr11_-_88718223 16.821 ENSMUST00000107909.1
 Msi2
musashi RNA-binding protein 2
chr11_-_102579071 16.805 ENSMUST00000107080.1
 Gm11627
predicted gene 11627
chr11_-_102579461 16.714 ENSMUST00000107081.1
 Gm11627
predicted gene 11627
chr2_+_71529085 16.682 ENSMUST00000152711.1
 Dlx1
distal-less homeobox 1
chr10_+_108332173 16.381 ENSMUST00000095313.3
 Pawr
PRKC, apoptosis, WT1, regulator
chr11_+_88718442 16.308 ENSMUST00000138007.1
 C030037D09Rik
RIKEN cDNA C030037D09 gene
chr6_-_95718800 15.469 ENSMUST00000079847.5
 Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,158 entries
Log-likelihood per target Total log-likelihoodTermDescription
15.6 46.7 GO:0097402 neuroblast migration(GO:0097402)
1.8 46.0 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
4.4 39.9 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
1.3 38.8 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
2.4 38.7 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
2.9 37.7 GO:0014841 skeletal muscle satellite cell proliferation(GO:0014841)
1.5 33.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
11.2 33.5 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
3.2 32.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
8.0 32.0 GO:0060032 notochord regression(GO:0060032)
3.4 30.8 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.8 29.9 GO:0051310 metaphase plate congression(GO:0051310)
0.3 29.3 GO:0051028 mRNA transport(GO:0051028)
9.6 28.8 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
7.2 28.7 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
3.5 28.0 GO:0048852 diencephalon morphogenesis(GO:0048852)
3.1 28.0 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
9.3 27.9 GO:0030421 defecation(GO:0030421)
4.6 27.4 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
2.8 25.6 GO:0097421 liver regeneration(GO:0097421)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 333 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 468.1 GO:0005634 nucleus(GO:0005634)
0.6 242.1 GO:0005667 transcription factor complex(GO:0005667)
0.4 132.4 GO:0031012 extracellular matrix(GO:0031012)
1.7 84.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.2 77.9 GO:0005844 polysome(GO:0005844)
1.1 57.5 GO:0000791 euchromatin(GO:0000791)
0.3 51.6 GO:0016324 apical plasma membrane(GO:0016324)
3.6 39.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 34.5 GO:0005759 mitochondrial matrix(GO:0005759)
2.3 29.9 GO:0097542 ciliary tip(GO:0097542)
0.1 25.8 GO:0000228 nuclear chromosome(GO:0000228)
0.1 25.4 GO:0005681 spliceosomal complex(GO:0005681)
0.2 25.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.5 23.8 GO:0005876 spindle microtubule(GO:0005876)
2.1 23.6 GO:0005915 zonula adherens(GO:0005915)
0.4 23.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 22.7 GO:0005814 centriole(GO:0005814)
1.4 21.9 GO:0010369 chromocenter(GO:0010369)
0.4 21.9 GO:0005902 microvillus(GO:0005902)
3.5 21.0 GO:0031262 Ndc80 complex(GO:0031262)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 628 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 235.9 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.6 105.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
1.1 83.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.6 58.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.8 55.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
2.1 46.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.7 45.5 GO:0071837 HMG box domain binding(GO:0071837)
2.1 45.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 42.8 GO:0003677 DNA binding(GO:0003677)
3.6 39.4 GO:0003680 AT DNA binding(GO:0003680)
0.7 38.6 GO:0001047 core promoter binding(GO:0001047)
1.5 37.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
2.0 35.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.9 32.6 GO:0050840 extracellular matrix binding(GO:0050840)
2.8 30.6 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.9 30.3 GO:0030332 cyclin binding(GO:0030332)
1.1 29.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
4.7 28.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
3.5 28.2 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
3.1 27.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)