Motif ID: Mbd2

Z-value: 1.268


Transcription factors associated with Mbd2:

Gene SymbolEntrez IDGene Name
Mbd2 ENSMUSG00000024513.10 Mbd2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mbd2mm10_v2_chr18_+_70568189_70568398-0.474.3e-05Click!


Activity profile for motif Mbd2.

activity profile for motif Mbd2


Sorted Z-values histogram for motif Mbd2

Sorted Z-values for motif Mbd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mbd2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_108003414 21.408 ENSMUST00000109887.1
ENSMUST00000109891.2
Bcl11b

B cell leukemia/lymphoma 11B

chr5_-_115194283 20.076 ENSMUST00000112113.1
Cabp1
calcium binding protein 1
chr5_+_37028329 14.427 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr5_+_36868467 14.097 ENSMUST00000031003.7
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr5_+_30588078 10.684 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr11_-_75796048 9.786 ENSMUST00000021209.7
Doc2b
double C2, beta
chr1_+_74854954 9.575 ENSMUST00000160379.2
Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr14_-_55116935 9.568 ENSMUST00000022819.5
Jph4
junctophilin 4
chr12_-_108003594 9.265 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr11_-_94474088 8.534 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr4_-_151861698 8.314 ENSMUST00000049790.7
Camta1
calmodulin binding transcription activator 1
chr13_-_52981027 8.173 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr4_-_151861762 8.077 ENSMUST00000097774.2
Camta1
calmodulin binding transcription activator 1
chr4_+_133039482 8.069 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr2_+_28205648 7.870 ENSMUST00000102879.3
ENSMUST00000028177.4
Olfm1

olfactomedin 1

chr11_+_104231390 7.783 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr11_-_102296618 7.702 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr7_+_29303958 7.646 ENSMUST00000049977.6
Dpf1
D4, zinc and double PHD fingers family 1
chr12_-_79007276 7.645 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr15_-_28025834 7.625 ENSMUST00000090247.5
Trio
triple functional domain (PTPRF interacting)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 176 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 33.9 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.3 31.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
5.1 30.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
2.0 28.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
1.5 16.9 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
1.1 10.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.6 9.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
2.4 9.6 GO:0021586 pons maturation(GO:0021586)
1.9 9.5 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.3 9.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 8.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.3 8.2 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.3 8.1 GO:0016578 histone deubiquitination(GO:0016578)
0.2 7.7 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.2 7.2 GO:0035418 protein localization to synapse(GO:0035418)
1.8 7.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.5 7.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 7.0 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 6.8 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 6.7 GO:0006457 protein folding(GO:0006457)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 29.5 GO:0045298 tubulin complex(GO:0045298)
0.5 22.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.5 19.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 18.6 GO:0000139 Golgi membrane(GO:0000139)
0.1 15.0 GO:0070382 exocytic vesicle(GO:0070382)
0.7 14.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.5 12.5 GO:0071565 nBAF complex(GO:0071565)
0.2 12.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 11.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 10.5 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.2 9.8 GO:0031201 SNARE complex(GO:0031201)
3.2 9.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.9 9.6 GO:0030314 junctional membrane complex(GO:0030314)
2.4 9.5 GO:1990032 parallel fiber(GO:1990032)
0.0 9.5 GO:0005768 endosome(GO:0005768)
0.1 9.3 GO:0030175 filopodium(GO:0030175)
0.1 8.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.6 7.5 GO:0000124 SAGA complex(GO:0000124)
0.4 7.2 GO:0099738 cell cortex region(GO:0099738)
0.1 7.1 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 29.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.6 25.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 16.3 GO:0005509 calcium ion binding(GO:0005509)
0.9 15.6 GO:0050811 GABA receptor binding(GO:0050811)
1.0 14.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 13.1 GO:0000287 magnesium ion binding(GO:0000287)
0.0 12.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.6 11.3 GO:0050321 tau-protein kinase activity(GO:0050321)
1.4 11.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.8 11.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.0 10.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 10.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 10.0 GO:0045499 chemorepellent activity(GO:0045499)
0.2 9.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
1.4 9.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 9.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 9.2 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.3 8.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
2.1 8.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 8.4 GO:0071889 14-3-3 protein binding(GO:0071889)