Motif ID: Mef2b

Z-value: 0.671


Transcription factors associated with Mef2b:

Gene SymbolEntrez IDGene Name
Mef2b ENSMUSG00000079033.3 Mef2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mef2bmm10_v2_chr8_+_70152754_701527810.191.1e-01Click!


Activity profile for motif Mef2b.

activity profile for motif Mef2b


Sorted Z-values histogram for motif Mef2b

Sorted Z-values for motif Mef2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Mef2b

PNG image of the network

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Top targets:


Showing 1 to 20 of 165 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103843154 12.802 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr6_-_23248264 7.918 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_-_142899985 6.048 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr7_-_144738478 5.648 ENSMUST00000121758.1
Ano1
anoctamin 1, calcium activated chloride channel
chrY_-_1286563 4.101 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr7_-_144738520 3.367 ENSMUST00000118556.2
ENSMUST00000033393.8
Ano1

anoctamin 1, calcium activated chloride channel

chr17_-_58991343 3.341 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr2_-_94264713 3.330 ENSMUST00000129661.1
E530001K10Rik
RIKEN cDNA E530001K10 gene
chr2_-_94264745 3.315 ENSMUST00000134563.1
E530001K10Rik
RIKEN cDNA E530001K10 gene
chr9_-_110742577 2.759 ENSMUST00000006005.7
Pth1r
parathyroid hormone 1 receptor
chr18_+_60963517 2.739 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr3_-_98814434 2.732 ENSMUST00000029463.6
Hsd3b6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
chr18_+_50030977 2.517 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr12_-_111672290 2.206 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr9_+_99629496 2.201 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
Dzip1l


DAZ interacting protein 1-like


chr2_+_120463566 2.160 ENSMUST00000028749.7
ENSMUST00000110721.1
Capn3

calpain 3

chr5_-_128953303 2.089 ENSMUST00000111346.1
Rimbp2
RIMS binding protein 2
chr3_-_20155069 2.083 ENSMUST00000184552.1
ENSMUST00000178328.1
Gyg

glycogenin

chrX_-_93832106 1.999 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr4_-_95052170 1.991 ENSMUST00000058555.2
Jun
Jun oncogene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 12.8 GO:0015671 oxygen transport(GO:0015671)
1.8 9.0 GO:0015705 iodide transport(GO:0015705)
1.3 7.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.5 6.0 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 4.2 GO:0042384 cilium assembly(GO:0042384)
0.1 4.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.8 3.8 GO:0045657 positive regulation of monocyte differentiation(GO:0045657) cellular response to potassium ion starvation(GO:0051365)
0.2 3.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.2 3.6 GO:1990481 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481)
1.0 3.0 GO:0042908 xenobiotic transport(GO:0042908)
0.2 2.8 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 2.7 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 2.7 GO:0006694 steroid biosynthetic process(GO:0006694)
0.1 2.5 GO:0032611 interleukin-1 beta production(GO:0032611)
0.6 2.3 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.7 2.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.4 2.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 2.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 2.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.5 2.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 12.8 GO:0005833 hemoglobin complex(GO:0005833)
0.2 9.5 GO:0034707 chloride channel complex(GO:0034707)
0.2 6.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 4.2 GO:0005814 centriole(GO:0005814)
0.0 4.1 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.1 3.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.9 3.6 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 3.1 GO:0001939 female pronucleus(GO:0001939)
0.1 2.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.6 GO:0031526 brush border membrane(GO:0031526)
0.1 2.1 GO:0031528 microvillus membrane(GO:0031528)
0.2 1.8 GO:0098536 deuterosome(GO:0098536)
0.0 1.8 GO:0036126 sperm flagellum(GO:0036126)
0.3 1.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 1.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.5 GO:0030315 T-tubule(GO:0030315)
0.2 1.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.4 GO:0030118 clathrin coat(GO:0030118)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.2 12.8 GO:0031721 hemoglobin alpha binding(GO:0031721)
2.3 9.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.0 6.0 GO:0035240 dopamine binding(GO:0035240)
0.0 5.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 4.1 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 3.8 GO:0035497 cAMP response element binding(GO:0035497)
0.2 3.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.9 3.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.9 3.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 2.8 GO:0017046 peptide hormone binding(GO:0017046)
0.9 2.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 2.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 2.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.6 2.2 GO:0004111 creatine kinase activity(GO:0004111)
0.3 2.2 GO:0031432 titin binding(GO:0031432)
0.2 2.1 GO:0005536 glucose binding(GO:0005536)
0.1 2.1 GO:0070402 NADPH binding(GO:0070402)
0.5 2.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 1.7 GO:0051525 NFAT protein binding(GO:0051525)