Motif ID: Mef2d_Mef2a
Z-value: 1.083


Transcription factors associated with Mef2d_Mef2a:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Mef2a | ENSMUSG00000030557.10 | Mef2a |
Mef2d | ENSMUSG00000001419.11 | Mef2d |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Mef2a | mm10_v2_chr7_-_67372846_67372858 | 0.71 | 3.9e-12 | Click! |
Mef2d | mm10_v2_chr3_+_88142328_88142483 | 0.68 | 1.0e-10 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 134 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 27.2 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
6.5 | 19.6 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
1.3 | 17.9 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
0.4 | 17.8 | GO:0034605 | cellular response to heat(GO:0034605) |
3.2 | 16.0 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
5.0 | 14.9 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
0.2 | 14.3 | GO:0001578 | microtubule bundle formation(GO:0001578) |
2.2 | 13.5 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.1 | 12.9 | GO:0050806 | positive regulation of synaptic transmission(GO:0050806) |
3.8 | 11.5 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
0.1 | 10.8 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
2.1 | 10.3 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
0.1 | 10.3 | GO:0006342 | chromatin silencing(GO:0006342) |
0.2 | 9.4 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
1.1 | 8.9 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
1.7 | 8.4 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
1.4 | 8.2 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
0.2 | 8.2 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
0.4 | 8.0 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
0.1 | 8.0 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 62 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 22.8 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.3 | 20.1 | GO:0014704 | intercalated disc(GO:0014704) |
0.9 | 17.9 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.0 | 17.6 | GO:0045202 | synapse(GO:0045202) |
0.3 | 16.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 15.6 | GO:0016607 | nuclear speck(GO:0016607) |
0.1 | 13.1 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.7 | 11.5 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.1 | 11.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
1.0 | 10.6 | GO:0043083 | synaptic cleft(GO:0043083) |
0.1 | 10.4 | GO:0043198 | dendritic shaft(GO:0043198) |
0.2 | 9.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.1 | 8.3 | GO:0005903 | brush border(GO:0005903) |
2.0 | 8.2 | GO:0090537 | CERF complex(GO:0090537) |
0.1 | 8.0 | GO:0016605 | PML body(GO:0016605) |
2.6 | 7.9 | GO:0043512 | inhibin A complex(GO:0043512) |
0.4 | 7.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.2 | 7.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.8 | 6.8 | GO:0001520 | outer dense fiber(GO:0001520) |
0.1 | 6.7 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 83 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 19.6 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
1.2 | 18.4 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
3.0 | 18.0 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.9 | 17.9 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.3 | 16.4 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.1 | 15.1 | GO:0008017 | microtubule binding(GO:0008017) |
0.8 | 15.0 | GO:0030275 | LRR domain binding(GO:0030275) |
2.3 | 13.7 | GO:0070699 | type II activin receptor binding(GO:0070699) |
1.2 | 13.7 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
0.4 | 13.5 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
0.1 | 13.1 | GO:0003729 | mRNA binding(GO:0003729) |
0.1 | 12.5 | GO:0005516 | calmodulin binding(GO:0005516) |
1.6 | 11.5 | GO:0032795 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
0.1 | 11.3 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
0.5 | 10.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
2.1 | 8.4 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
2.7 | 8.2 | GO:0070615 | nucleosome-dependent ATPase activity(GO:0070615) |
0.1 | 7.7 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.4 | 7.6 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.2 | 7.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |